Special Issue "Pathophysiology and Neuroprotective Strategies in Hypoxic-Ischemic Brain Injury and Stroke"
A special issue of Brain Sciences (ISSN 2076-3425).
Deadline for manuscript submissions: closed (28 February 2018) | Viewed by 19599
2. Centre for Neuromuscular and Neurological Disorders, the University of Western Australia, Nedlands, WA 6009, Australia
3. Department of Neurosurgery, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia
Interests: Neuroprotection; Stroke; Hypoxic-ischaemic encephalopathy; Traumatic brain injury; In vitro neuronal cell injury models
Special Issues, Collections and Topics in MDPI journals
Special Issue in Biomedicines: Stroke and Neuroprotection
Special Issue in Brain Sciences: Neuroprotection in Neonatal Encephalopathy
Hypoxic-ischemic brain injury and stroke are devastating conditions which can affect individuals at any age from birth to old age. Acute brain injury resulting from stroke and hypoxic-ischaemic (HI) episodes, including perinatal HI encephalopathy (HIE) and global cerebral ischemia together, are one of the major causes of death and disability worldwide. Despite considerable research over many years, there are still no clinically effective pharmacological neuroprotective treatments capable of reducing the severity of brain injury in these situations. As a consequence, the development of an effective pharmacological neuroprotective agent for individuals suffering a stroke or a hypoxic-ischemic event remains an urgent unmet need.
Furthermore, many of the pathophysiological events associated with ischaemic and hypoxic brain injury have not been fully elucidated and therefore further studies are required in this area. Ultimately, a better understanding of the pathophysiology of ischaemic and hypoxic brain injury will aid the develeopment of new and effective neuroprotective therapies. Hence, the aim of this Special Issue is to encourage the publication of new experimental and clinical findings to advance our understanding of the pathogenic processes and the development of neuroprotective strategies following hypoxic-ischemic brain injury and stroke.
Prof. Bruno Meloni
Manuscript Submission Information
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- Hypoxic-ischemic brain injury
- Global cerebral ischemia
- Perinatal hypoxic-ischemic encephalopathy
- Neuronal death