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Brain Sciences
Special Issues
Cognitive Impairments after Brain Injury
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Cognitive Impairments after Brain Injury

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Systems Neuroscience".

Deadline for manuscript submissions: closed (30 October 2024) | Viewed by 2061

Special Issue Editors

Dr. Vasileios Papaliagkas

E-Mail Website
Guest Editor
Department of Biomedical Sciences, International Hellenic University, Thessaloniki, Greece
Interests: Alzheimer's disease; mild cognitive impairment; cerebrospinal fluid; beta amyloid; neurodegenerative diseases; neurodegeneration; cognition disorders; event-related potentials; evoked potentials
Special Issues, Collections and Topics in MDPI journals
Dr. Ioannis Asterios Mavroudis

E-Mail Website
Guest Editor
Leeds Teaching Hospitals NHS Trust, Leeds, UK
Interests: brain injuries; neurodegeneration; neurodegenerative diseases; epilepsy; traumatic brain injury; functional neurological disorder; neuromuscular disease; dementia; cognitive science and artificial thinking
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are excited to announce an upcoming Special Issue titled "Cognitive Impairments after Brain Injury", to be published in the respected Brain Sciences journal. As co-editors, Professor Papaliagkas and Dr. Mavroudis cordially invite you to contribute your valuable research and insights to this significant publication.

This Special Issue aims to explore the multifaceted aspects of cognitive impairments resulting from brain injuries. The scope of this Special Issue encompasses a wide range of topics, including, but not limited to, the mechanisms of cognitive decline post-injury, advances in diagnostic methodologies, novel therapeutic approaches, and long-term management strategies. We are particularly interested in papers that address innovative research findings, interdisciplinary approaches, and comprehensive reviews that can contribute to a deeper understanding of this complex subject.

Contributions from a diverse range of disciplines, such as neurology, psychology, rehabilitation medicine, and neuroscience, are welcome, as we believe that a multidisciplinary approach is crucial in addressing the challenges posed by cognitive impairments after brain injuries.

The deadline for manuscript submissions is October 2024. We encourage you to submit original research articles, review papers, case studies, and short communications that align with the theme of our Special Issue. Detailed submission guidelines can be found on the Brain Sciences journal's website.

Your participation in this Special Issue will not only contribute to the advancement of our understanding of cognitive impairments post-brain injury but will also offer an opportunity to highlight your important work in this field. We look forward to receiving your submissions and to the possibility of showcasing your valuable research.

For any queries or further discussion regarding potential topics, please do not hesitate to contact us.

Dr. Vasileios Papaliagkas
Dr. Ioannis Asterios Mavroudis
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • neurorehabilitation
  • neuropsychology
  • traumatic brain injury (TBI)
  • neuroplasticity
  • cognitive rehabilitation
  • brain imaging techniques

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Published Papers (1 paper)

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14 pages, 2441 KiB  
Systematic Review
The Association Between Traumatic Brain Injury and the Risk of Cognitive Decline: An Umbrella Systematic Review and Meta-Analysis
by Ioannis Mavroudis, Dimitrios Kazis, Foivos Efstratios Petridis, Ioana-Miruna Balmus, Vasileios Papaliagkas and Alin Ciobica
Brain Sci. 2024, 14(12), 1188; https://doi.org/10.3390/brainsci14121188 - 26 Nov 2024
Viewed by 1382
Abstract
Background: There is currently increasing interest in the implication of traumatic brain injury (TBI) as a potential risk factor for long-term neurodegenerative conditions, such as dementia and Alzheimer’s disease (AD). In this context, we performed a systematic review and meta-analysis to evaluate the [...] Read more.
Background: There is currently increasing interest in the implication of traumatic brain injury (TBI) as a potential risk factor for long-term neurodegenerative conditions, such as dementia and Alzheimer’s disease (AD). In this context, we performed a systematic review and meta-analysis to evaluate the association between TBI and the risk of dementia. Methods: A systematic search was performed across multiple electronic databases, including PubMed, Embase, and Cochrane Library, to identify relevant meta-analyses and cohort studies. Studies were included if they reported effect sizes (odds ratios [ORs] or relative risks [RRs]) for the association between TBI, its severity, and the risk of dementia or AD. Meta-analyses were performed using random-effects models to account for heterogeneity, and sensitivity analyses were conducted. Results: A total of six studies were included in the analysis. The pooled results showed that TBI significantly increases the risk of dementia, with an overall odds ratio of 1.81 (95% CI: 1.53–2.14). Mild TBI was associated with a modest increase in dementia risk (OR = 1.96, 95% CI: 1.70–2.26), while moderate-to-severe TBI showed a stronger association (OR = 1.95, 95% CI: 1.55–2.45). In contrast, the association between TBI and AD was less consistent, with the pooled OR for AD being 1.18 (at 95% CI: 1.11–1.25) for mild TBI; however, in several studies, no significant association was observed (OR = 1.02, 95% CI: 0.91–1.15). The results also indicated substantial heterogeneity across studies, particularly in relation to AD outcomes. Conclusions: The findings from this umbrella meta-analysis confirm that TBI is a significant risk factor for dementia, with more severe TBIs conferring a higher risk. While mild TBIs also increase the risk of dementia, the effect is more pronounced in moderate-to-severe injuries. The evidence linking TBI to AD is less robust, with inconsistent findings across studies. Clinicians should consider long-term cognitive screening and management for individuals with a history of TBI, particularly those with moderate-to-severe injuries. Full article
(This article belongs to the Special Issue Cognitive Impairments after Brain Injury)
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