Central Aspects of Tinnitus: Advances in Mechanisms and Neuromodulation
Deadline for manuscript submissions: 29 March 2024 | Viewed by 1791
Interests: tinnitus; hearing disorders; neuromodulation
2. School for Mental Health and Neuroscience, Maastricht University, 6229 ER Maastricht, The Netherlands
Interests: deep brain stimulation; neuromodulation; neurophysiology; tinnitus; movement disorders
Special Issues, Collections and Topics in MDPI journals
The auditory pathway is a complex system that processes neural signals from the cochlea to the auditory cortex, where the actual perception of sound occurs. Within this pathway, a number of sophisticated processes take place, such as sound localization and the filtering of sounds. Pathology within this system can result in hearing loss (e.g., tumor or stroke) but also hyperacusis and tinnitus. While hearing loss is usually of a peripheral origin and tinnitus and hyperacusis are triggered by peripheral pathology, the brain plays a crucial role in these pathologies.
Although the prevalence and burden of persons with tinnitus is high, to date, none of the available tinnitus treatments have been proven to be effective for most tinnitus patients. Neuromodulation is currently gaining more interest as an avenue to explore for tinnitus treatment. Noninvasive neuromodulation has been shown to be effective in some tinnitus patients in the short term. Additionally, invasive techniques such as deep brain stimulation and auditory brain stem implants are currently being studied. A better understanding of the central auditory pathway supports further development of the objective measurement of hearing (e.g., auditory brainstem response) and may support further development of both non-invasive and invasive neuromodulation therapies such as auditory brainstem implants for hearing loss, deep brain stimulation, and transcranial magnetic stimulation for tinnitus.
This Special Issue of Brain Sciences aims to provide more insight into the central mechanism and therapeutics of hearing(-related) disorders. Authors are invited to submit research and reviews that address a broad range of topics, such as central aspect of hearing disorders, pathophysiology of tinnitus, hearing loss and hyperacusis, diagnostics related to the auditory pathways, invasive and non-invasive neuromodulation for (central) hearing loss, tinnitus, and hyperacusis.
Dr. Jasper V. Smit
Dr. Marcus L. F. Janssen
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- hearing disorders
- auditory pathway