Aptamer and Oligonucleotide-Based Electrochemical Biosensors for Environmental Analysis

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 1815

Special Issue Editors


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Guest Editor
Applied Biophysics and Surface Science Group, Bio-Medical Research Foundation of the Academy of Athens (BRFAA), Athens, Greece
Interests: biointerfaces; aptamers; surface (bio)functionalization; material-independent chemis-tries; biosensors; lab-on-a chip; NEMS; microfluidics; point-of-need; medical diagnostics; food safety; drug screening; environmental monitoring
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Guest Editor
Politechnika Warszawskadisabled, Warsaw, Poland
Interests: “affinity” biosensors; point-of-care” (POC) device; clinical diagnostics; protein biomarkers

Special Issue Information

Dear Colleagues,

Constant monitoring of the quality of drinking water is necessary as it is vital for proper functioning of living organisms. Ground and surface water is exposed to contamination due to, for instance, urbanisation, industry and mining. Hence, it is crucial to elaborate sensitive, selective and portable methods for the analysis of water samples in situ. One of the possibilities is the application of electrochemical biosensors combined with aptamer and oligonucleotide-based sensing layers. Hence, this Special Issue of Biosensors will be dedicated to current achievements in the field of the utilization of such tools in environmental analysis.

Dr. George Tsekenis
Dr. Marta Jarczewska
Guest Editors

Manuscript Submission Information

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Keywords

  • biosensors
  • electrochemistry
  • aptamers
  • oligonucleotides
  • miniaturization

Published Papers (1 paper)

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Research

18 pages, 3319 KiB  
Article
Studies on the Aptasensor Miniaturization for Electrochemical Detection of Lead Ions
by Marta Jarczewska, Marta Sokal, Marcin Olszewski and Elzbieta Malinowska
Biosensors 2024, 14(2), 110; https://doi.org/10.3390/bios14020110 - 19 Feb 2024
Viewed by 1595
Abstract
Lead poses severe effects on living organisms, and since Pb2+ ions tend to accumulate in different organs, it is crucial to monitor Pb2+ concentration in samples such as water and soil. One of the approaches is the utilization of biosensors combined [...] Read more.
Lead poses severe effects on living organisms, and since Pb2+ ions tend to accumulate in different organs, it is crucial to monitor Pb2+ concentration in samples such as water and soil. One of the approaches is the utilization of biosensors combined with aptamer-based layers for the electrochemical detection of lead ions. Herein, we present the studies of applying miniaturized screen-printed transducers as solid surfaces to fabricate aptamer layers. As the research is the direct continuation of our previous studies regarding the use of gold disk electrodes, the working parameters of elaborated aptasensors were defined, including the range of linear response (10–100 nM), selectivity as well as stability, regeneration, and feasibility of application for the analysis of real samples. This was achieved using voltammetric techniques including cyclic and square-wave voltammetry in the presence of methylene blue redox indicator. Full article
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