Nature Inspired Peptides in Medical Sciences
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Cellular Biochemistry".
Deadline for manuscript submissions: closed (15 December 2022) | Viewed by 29707
Special Issue Editor
Interests: bioinspired peptide dendrimers, dendrimer chemistry; nanomolecular antioxidants and free radical scavengers; chiral coordination polymers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Biomolecules invites submissions to a Special Issue focused on the chemistry, biology, and medical application of natural peptides and their mimetics in recognition of Nature’s remarkable inspiration for gaining new ideas for future medicine.
Cationic, often amphiphilic, peptides with antimicrobial, antifungal, anticancer, etc., properties have been discovered in all forms of life and demonstrated a prominent role in executing the functions of life. Inspired by Nature, antimicrobial peptides (AMPs) and their synthetic analogs, with a predominantly nonspecific mode of action, are rapidly gaining attention for their clinical potential as novel antibiotics that are much less prone to drug resistance. It has recently been discovered that, beyond their antimicrobial activity inherently supporting the innate immune system, AMPs display tumor suppressive effect and influence signaling cascades that stimulate activity of the adaptive immune system. Rationally designed variations in cell penetrating peptides (CPP) have demonstrated promising potentials for drug delivery.
Numerous recent studies point to an increasing role of peptides as potential therapeutics for the treatment of a broad range of diseases. Consequently, an increasing number of peptide drug candidates that were inspired by Nature have progressed to phase clinical trials.
For this Special Issue, we invite submissions of papers focusing on understanding the challenges and opportunities for clinical development with this emerging therapeutic class.
Prof. Zofia Urbanczyk-Lipkowska
Guest Editor
Manuscript Submission Information
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Keywords
- methodology of natural peptides discovery, synthesis and characterization
- studies on molecular mechanism of action
- interactions with biological systems (proteins, DNA, RNA)
- bioinspired peptides as drug delivery systems
- clinical aspects of bioinspired peptides application
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