Natural Compounds with Biomedical Potential
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Chemical Biology".
Deadline for manuscript submissions: 31 March 2027 | Viewed by 1073
Special Issue Editors
Interests: diabetes; antioxidants; oxidative stress; lipid peroxidation; catalase; diabetes mellitus; superoxide dismutase; nutritional medicine; reactive oxygen species; metabolism
Interests: computational chemistry; drug discovery; medicinal chemistry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Natural bioactive compounds comprise a vast area of molecules derived from plants, fungi, marine organisms, and other natural sources. The exploration of this field of interest has emerged as a cornerstone in biomedical research, driven by an ascending appreciation of the potential therapeutic benefits of natural compounds and contributions to human health. Over the years, they gained considerable attention due to their efficacy and their relatively lower toxicity, compared to their synthetic counterparts. Another advantage is assured by the natural extratcs, which gather multiple bioactive compounds, which offer synergy in activity or may even broaden the therapeutic potential.
An extremely important characteristic of natural compounds is their structural diversity, related to a large spectra of biological activities and mechanisms of action. Polyphenols, terpenoids, alkaloids, phytosterols, organosulphur compounds, saponins or glycosides, each category exhibits unique chemical profile that decide their interactions with biological targets. Therefore, their beneficial activities cover a large area, ranging from antimicrobial, antioxidant, anti-inflammatory properties to antidiabetes and anticancer effects, reflecting their potential as therapeutic agents in human health. Their natural origin offer the possibility to associate them with synthetic drugs, offering the premises of a potentialized effect or even multiple therapeutic effects.
Understanding the interactions of natural bioactive compounds with biological systems and harnessing them for therapeutic purposes represents a very promising direction in drug discovery and development.
Dr. Irina Camelia Chis
Dr. Cristina Mariana Moldovan
Guest Editors
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Keywords
- natural compounds
- naturat extracts
- drug discovery
- antimicrobial activity
- antioxidant activity
- anticancer activity
- anti-inflammatory activity
- anti-diabetes activity
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