Special Issue "Models of CNS Regeneration: Mind the Gap!"

A special issue of Biology (ISSN 2079-7737).

Deadline for manuscript submissions: 30 April 2019

Special Issue Editor

Guest Editor
Prof. Eustace Johnson

Stem Cells and Regenerative Biology, Faculty of Medicine Dentistry & Life Sciences, University of Chester, Chester, United Kingdom
Website | E-Mail
Interests: stem cell biology; central nervous system; tissue repair and regeneration; model organisms; clinical translation

Special Issue Information

Dear Colleagues,

The regeneration of the central nervous system (CNS) remains an elusive target for basic researchers and clinicians in regenerative medicine. Progress in rodent models using stem cells to decrease the catastrophic effects of CNS damage and increase axonal growth has failed to translate to successful clinical treatment of humans. Clearly, there is a knowledge gap. This Special Issue aims to help bridge this gap by addressing how alternative approaches have been used to better understand mechanisms of CNS regeneration. Contributions from researchers across the field will present the latest research findings and discuss how this research helps provide a bigger picture of CNS regeneration across species and across evolutionary pressures, including in vivo, ex vivo, and in vitro models, encompassing adult stem cells, pluripotent stem cells, plasticity, systemic issues, and the wound microenvironment. In this way, the Special Issue will provide both an overview of our current knowledge from these alternative models and bring together expert opinion on what still needs to be discovered and translated to help improve the likelihood of successfully regenerating the human CNS.

Prof. Eustace Johnson
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 650 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • stem cell biology
  • central nervous system
  • axonal regeneration
  • model organism
  • in vivo
  • in vitro
  • clinical translation

Published Papers

This special issue is now open for submission.
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