Special Issue "Applications of Proteomics in Immunology"
Deadline for manuscript submissions: 31 October 2023 | Viewed by 353
The immune system is our defense mechanism against microbial infections and tissue injury. A detailed understanding of this highly complex and multifacted system is essential for developing drugs to combat different diseases. The immune system includes multiple defense mechanisms including innate and adaptive cell-mediated immune responses, both of which need to be carefully controlled to activate an appropriate immune response.
Proteomics can provide in-depth spatiotemporal information about proteins on a global scale. In particular, mass spectrometry (MS)-based proteomics has developed immensely since the turn of the century, and recent developments in proteomics sample preparation, new high-resolution MS-instruments, as well as advances in data-analysis tools have enabled unprecedented speed and sensitivity in the charactersation of the proteome. With current methods and instruments, we have started to acheive single-cell sensitivity by mass spectrometry.
For this Special Issue, ‘Applications of Proteomics in Immunology’, I invite authors to submit original articles as well as reviews that focus on the contiribution of proteomics to new knowledge in the field of immune system function and regulation. Studies using human and model organisms are welcome, as well as proteomic studies applied to clinical immunology research.
Topics of special interest include:
- proteomics to characterise the role of extracellular vesicles in immune response;
- detailed understanding of molecular mechanisms of inflammation;
- how proteomics can contribute to clinical research.
I look forward to receiving your contributions.
Dr. Tuula Nyman
Manuscript Submission Information
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- biological mass spectrometry
- innate immunity
- T and B cell immune response
- extracellular vesicles
- clinical proteomics