Special Issue "Selected Papers from XXI SPB National Congress of Biochemistry 2021"

A special issue of BioChem (ISSN 2673-6411).

Deadline for manuscript submissions: 31 July 2022 | Viewed by 3557

Special Issue Editors

Prof. Dr. Manuel Aureliano
E-Mail Website1 Website2
Guest Editor
1. Faculdade de Ciências e Tecnologia (FCT), Campus de Gambelas, Universidade do Algarve, 8005-139 Faro, Portugal
2. CCMAR, Campus de Gambelas, Universidade do Algarve, 8005-139 Faro, Portugal
Interests: role and applications of metals in molecular sciences; decavanadate biochemistry; polyoxometalate (POM) interactions with proteins; metals and biomedical applications
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. M. Leonor Cancela
E-Mail Website
Guest Editor
Ctr Marine Sci CCMAR, Univ Algarve, 8005-139 Faro, Portugal
Interests: biomedicine; model organism; bone development; extracts from marine organisms; colorectal cancer; biomarker; vitamin
Special Issues, Collections and Topics in MDPI journals
Dr. Célia M. Antunes
E-Mail Website
Guest Editor
Department of Medical and Health Sciences, School of Health and Human Development & ICT-Institute of Earth Sciences, University of Évora, Evora, Portugal
Interests: cell culture; signaling pathways; cell signaling; phosphorylation; signal transduction; allergens; aerobiology; Bioaerosols; Metabolism; Enrironmental Health; molecular allergology
Special Issues, Collections and Topics in MDPI journals
Dr. Ana Cristina Rodrigues Costa
E-Mail Website
Guest Editor
Department of Medical and Health Sciences, School of Health and Human Development & ICT - Institute of Earth Sciences, University of Évora, Évora, Portugal
Interests: molecular basis of disease; biochemical toxicology and pharmacology; biomearkers development

Special Issue Information

Dear Colleagues,

The XXI SPB National Congress of Biochemistry 2021 was held at the University of Évora in Portugal on 14–16 October 2021. This is the meeting point for the Portuguese Biochemistry Society, fostering discussion and dissemination of high-quality research in Biochemistry, both fundamental and applied, taking place in Portugal. The scientific program under the message “Tuning Biochemistry with Life Sciences and Society” covers a broad range of boundaries from molecular mechanisms of diseases to drug discovery, as well as innovative biochemistry projects. Science and innovation are promoted through dialogue, sharing, and healthy confraternization.

This Special Issue includes but is not limited to the following topics:

  • Molecular mechanisms of disease; 
  • Plant biology and biotechnology;
  • Toxicology and environmental biochemistry;
  • Structural biology and molecular modeling;
  • SPB-SPN: neurobiology of aging and stress;
  • Functional genomics and systems biology;
  • Membranes and cell biophysics;
  • SBBq—proteins in health and environment;
  • SEBBM—chemical biology, drug discovery, and development;
  • Art, biochemistry, and innovation in life sciences;
  • COVID-19 special session.

For more details, please visit: http://www.xxispbcongress2020.uevora.pt/

Prof. Dr. Manuel Aureliano
Prof. Dr. M. Leonor Cancela
Prof. Dr. Célia M. Antunes
Dr. Ana Rodrigues Costa
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. BioChem is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • molecular mechanisms of disease
  • plant biology and biotechnology
  • toxicology and environmental biochemistry
  • structural biology and molecular modeling
  • sPB-SPN: neurobiology of aging and stress
  • functional genomics and systems biology
  • membranes and cell biophysics
  • SBBq—proteins in health and environment
  • SEBBM—chemical biology, drug discovery, and development
  • art, biochemistry, and innovation in life sciences
  • COVID-19 special session

Published Papers (5 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

Jump to: Review

Communication
UALGORITMO, a New Instrument of the University of Algarve for Scientific Outreach
BioChem 2022, 2(1), 93-103; https://doi.org/10.3390/biochem2010007 - 03 Mar 2022
Viewed by 553
Abstract
Researchers at Universities generate and convey the knowledge acquired through communications in specialized (inter)national journals and congresses. An effort to share the scientific achievements with the general public is extremely important. For this purpose, we have launched the UALGORITMO, a journal freely accessible [...] Read more.
Researchers at Universities generate and convey the knowledge acquired through communications in specialized (inter)national journals and congresses. An effort to share the scientific achievements with the general public is extremely important. For this purpose, we have launched the UALGORITMO, a journal freely accessible online, written in lay Portuguese language by Researchers of the University of the Algarve, to summarize recent communications published in peer reviewed journals. After submission, the manuscripts are revised by High Schools Students of the Algarve, under the guidance of a schoolteacher, for further simplification of the language and general improvement of the manuscript and figures. The revised manuscripts by the authors are edited and published, with an acknowledgment and a presentation of the reviewers at the end of each article. To maximize the outreach, the articles include a summarized biography of the authors, and links to their research centers and teaching courses. We believe that the UALGORITMO is a valuable instrument to promote scientific literacy and culture amongst all communities. Full article
(This article belongs to the Special Issue Selected Papers from XXI SPB National Congress of Biochemistry 2021)
Show Figures

Figure 1

Review

Jump to: Research

Review
Biological Activity of Gold Compounds against Viruses and Parasitosis: A Systematic Review
BioChem 2022, 2(2), 145-159; https://doi.org/10.3390/biochem2020010 - 14 May 2022
Viewed by 337
Abstract
In this contribution, we provide an overview of gold compound applications against viruses or parasites during recent years. The special properties of gold have been the subject of intense investigation in recent years, which has led to the development of its chemistry with [...] Read more.
In this contribution, we provide an overview of gold compound applications against viruses or parasites during recent years. The special properties of gold have been the subject of intense investigation in recent years, which has led to the development of its chemistry with the synthesis of new compounds and the study of its applicability in various areas such as catalysis, materials, nanotechnology and medicine. Herein, thirteen gold articles with applications in several viruses, such as hepatitis C virus (HCV), influenza A virus (H1N1), vesicular stomatitis virus (VSV), coronavirus (SARS-CoV and SARS-CoV-2), Dengue virus, and several parasites such as Plasmodium sp., Leishmania sp., Tripanossoma sp., Brugia sp., Schistosoma sp., Onchocerca sp., Acanthamoeba sp., and Trichomonas sp. are described. Gold compounds with anti-viral activity include gold nanoparticles with the ligands mercaptoundecanosulfonate, 1-octanethiol and aldoses and gold complexes with phosphine and carbene ligands. All of the gold compounds with anti-parasitic activity reported are gold complexes of the carbene type. Auranofin is a gold drug already used against rheumatoid arthritis, and it has also been tested against virus and parasites. Full article
(This article belongs to the Special Issue Selected Papers from XXI SPB National Congress of Biochemistry 2021)
Show Figures

Figure 1

Review
Translating Biochemistry Concepts into Cartoons and Graphic Narratives: Potential and Pitfalls
BioChem 2022, 2(1), 104-114; https://doi.org/10.3390/biochem2010008 - 17 Mar 2022
Viewed by 470
Abstract
Simple biochemical concepts can be hard to grasp by non-specialists, even when they are related to practical contexts in industry, day-to-day activities, or well-acknowledged pathological conditions. This is especially important in instances where accurate communication of biochemical aspects for different types of stakeholders [...] Read more.
Simple biochemical concepts can be hard to grasp by non-specialists, even when they are related to practical contexts in industry, day-to-day activities, or well-acknowledged pathological conditions. This is especially important in instances where accurate communication of biochemical aspects for different types of stakeholders may be crucial. Examples include interacting with policymakers to establish guidelines, with patients (and/or caregivers) to identify key concepts in promoting awareness and adherence to therapeutic regimens, or with teachers and students for novel approaches in critical thinking. Focusing on our own work in developing communication tools for different purposes, in this review we will focus on some examples of how biochemical concepts can be effectively translated into illustrations and graphical narratives. For this purpose, engagement with target audiences in developing the materials themselves is key. We also discuss how specific projects can be tailored for different purposes, as well as evidence that comic-book strategies are effective in conveying biochemical and biomedical knowledge. Full article
(This article belongs to the Special Issue Selected Papers from XXI SPB National Congress of Biochemistry 2021)
Show Figures

Figure 1

Review
Heme-Based Gas Sensors in Nature and Their Chemical and Biotechnological Applications
BioChem 2022, 2(1), 43-63; https://doi.org/10.3390/biochem2010004 - 08 Feb 2022
Viewed by 752
Abstract
Sensing is an essential feature of life, where many systems have been developed. Diatomic molecules such as O2, NO and CO exhibit an important role in life, which requires specialized sensors. Among the sensors discovered, heme-based gas sensors compose the largest [...] Read more.
Sensing is an essential feature of life, where many systems have been developed. Diatomic molecules such as O2, NO and CO exhibit an important role in life, which requires specialized sensors. Among the sensors discovered, heme-based gas sensors compose the largest group with at least eight different families. This large variety of proteins also exhibits many distinct ways of sensing diatomic molecules and promote a response for biological adaptation. Here, we briefly describe a story of two impressive systems of heme-based oxygen sensors, FixL from Rhizobium and DevS(DosS)/DosT from Mycobacterium tuberculosis. Beyond this, we also examined many applications that have emerged. These heme-based gas sensors have been manipulated to function as chemical and biochemical analytical systems to detect small molecules (O2, CO, NO, CN), fluorophores for imaging and bioanalysis, regulation of processes in synthetic biology and preparation of biocatalysts among others. These exciting features show the robustness of this field and multiple opportunities ahead besides the advances in the fundamental understanding of their molecular functioning. Full article
(This article belongs to the Special Issue Selected Papers from XXI SPB National Congress of Biochemistry 2021)
Show Figures

Figure 1

Review
The Future Is Bright for Polyoxometalates
BioChem 2022, 2(1), 8-26; https://doi.org/10.3390/biochem2010002 - 06 Jan 2022
Viewed by 757
Abstract
Polyoxometalates (POMs) are clusters of units of oxoanions of transition metals, such as Mo, W, V and Nb, that can be formed upon acidification of neutral solutions. Once formed, some POMs have shown to persist in solution, even in the neutral and basic [...] Read more.
Polyoxometalates (POMs) are clusters of units of oxoanions of transition metals, such as Mo, W, V and Nb, that can be formed upon acidification of neutral solutions. Once formed, some POMs have shown to persist in solution, even in the neutral and basic pH range. These inorganic clusters, amenable of a variety of structures, have been studied in environmental, chemical, and industrial fields, having applications in catalysis and macromolecular crystallography, as well as applications in biomedicine, such as cancer, bacterial and viral infections, among others. Herein, we connect recent POMs environmental applications in the decomposition of emergent pollutants with POMs’ biomedical activities and effects against cancer, bacteria, and viruses. With recent insights in POMs being pure, organic/inorganic hybrid materials, POM-based ionic liquid crystals and POM-ILs, and their applications in emergent pollutants degradation, including microplastics, are referred. It is perceived that the majority of the POMs studies against cancer, bacteria, and viruses were performed in the last ten years. POMs’ biological effects include apoptosis, cell cycle arrest, interference with the ions transport system, inhibition of mRNA synthesis, cell morphology changes, formation of reaction oxygen species, inhibition of virus binding to the host cell, and interaction with virus protein cages, among others. We additionally refer to POMs’ interactions with various proteins, including P-type ATPases, aquoporins, cinases, phosphatases, among others. Finally, POMs’ stability and speciation at physiological conditions are addressed. Full article
(This article belongs to the Special Issue Selected Papers from XXI SPB National Congress of Biochemistry 2021)
Show Figures

Figure 1

Back to TopTop