Potential Biomarkers in Tears

Dear Colleagues,

We are pleased to invite you to submit papers regarding this Special Issue concerning the potential biomarkers in tears. The issue intends to deliver an overview of the current knowledge in this field by bringing together studies about potential biomarkers (e.g., diagnostic, response, predictive, prognostic, susceptibility, therapeutic) in tears and also about their application.

Tear biomarkers are playing an increasingly important role in the field of predictive, preventative and personalized medicine. Through proteomic, metabolomic, and lipidomic analysis, several molecules and/or panels of a combination of several of them have been pointed out as promising biomarkers in several ocular diseases, particularly in dry eye disease, but also in several others such as ocular chronic allergy, glaucoma, keratoconus, keratopathy, keratitis, trachoma, aniridia or uveitis among others. Additionally, biomarkers have proven their usefulness in systemic diseases such as diabetic retinopathy, systemic sclerosis, cystic fibrosis, cancer, or in neurological disorders such as multiple sclerosis or Parkinson’s disease. Tear biomarkers can serve as indicators of disease severity, activity or therapeutic response, and they are considered as good candidates to be used as objective evaluation endpoints for objective monitoring in clinical trials. They also increase the knowledge about the molecular mechanisms underlying diseases. Additionally, biomarkers in tears can be used to establish responsive profiles which may allow for the identification of patients with a predictable response or susceptibility to a given condition.

Dr. Amalia Enríquez-de-Salamanca
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.