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Advances in Food Metabolomics

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Food Science and Technology".

Deadline for manuscript submissions: closed (30 October 2024) | Viewed by 1586

Special Issue Editors


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Guest Editor
Department of Molecular Biotechnology and Health Sciences, University of Torino, Via Pietro Giuria 5, 10125 Torino, Italy
Interests: mass spectrometry; chromatography; food chemistry; metabolomics
Special Issues, Collections and Topics in MDPI journals

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Guest Editor Assistant
Department of Agronomy, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, SI-1000 Ljubljana, Slovenia
Interests: metabolomics; secondary metabolism; biochemistry; food analysis; plant physiology

Special Issue Information

Dear Colleagues,

Metabolomics is a relatively new component of systems biology that was first proposed in 1999 and focuses on the high-throughput characterization of small-molecule metabolites in biological systems. Metabolomics has emerged as a technology for studying changes in metabolism and the response of organisms to external and internal environmental influences, and it has been widely used in various scientific fields, particularly in the food sector, where its excellent detection and prediction capabilities make it highly suitable for the analysis of more complex matrices. Metabolomics is mainly used in food composition analysis and studies regarding food quality safety and food traceability. Metabolomics is a comprehensive and systematic analytical method that has the potential to elucidate the mechanisms of action of bioactive components, find new biomarkers, and evaluate metabolic disease management interventions and nutritional interventions. Metabolomics has gained a great deal of importance, especially after the development of new technologies such as ultra-high-performance liquid chromatography (UHPLC), matrix-assisted laser desorption/ionization (MALDI) and capillary electrophoresis (CE). These technologies have proven to be particularly useful in the food sector, as they are excellent for detecting complex metabolomes or elucidating their structure. The use of metabolomics technologies enables the monitoring of metabolite changes during food processing, which allows for the optimization of processing methods and the improvement of product quality because, as we all know, food metabolites can be and usually are influenced by various factors (animal species, environment, processing and storage methods) that can directly affect food quality and safety. These potentially harmful components of food processing and manufacturing (food toxins and drug residues) can be identified using metabolomics technology to ensure human health. With the improvements in science and technology in recent years, the adulteration of food through the addition of food additives or other additives is becoming more common. In addition, there are also adulteration methods that involve using similar but cheap ingredients to ensure that they final food product can masquerade as an expensive food. Conventional analytical methods usually have limitations, such as long identification times and low identification accuracy, making it difficult to solve these problems. However, by using advanced food metabolomics techniques, changes in food composition can be easily observed, especially in terms of food composition, safety, classification, and traceability. This Special Issue is dedicated to advances in food metabolomics and its role in analyzing food composition, food safety, food traceability, and food classification. Emphasis is placed on the use of new metabolomics technologies that have been applied to food science in recent years, as well as the potential applications of metabolomics technologies in the food industry. However, other high-quality contributions related to the field of food metabolomics will also be considered.

Prof. Dr. Claudio Medana
Guest Editor

Dr. Aljaz Medic
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • secondary metabolism
  • volatile compounds
  • food analysis
  • innovative technologies
  • food quality
  • food composition analysis
  • food safety

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Published Papers (1 paper)

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Research

16 pages, 4541 KiB  
Article
Untargeted Metabolomic Profiling of Fructus Chebulae and Fructus Terminaliae Billericae
by Yuman Song and Hede Gong
Appl. Sci. 2024, 14(7), 3123; https://doi.org/10.3390/app14073123 - 8 Apr 2024
Viewed by 1048
Abstract
This study aims to identify the differences in metabolites between Fructus Chebulae (FC) and Fructus Terminaliae Billericae (FTB). Untargeted metabolomics was used to analyze differentially expressed metabolites (DEMs) with ultra-performance liquid chromatography–electrospray ionization–tandem mass spectrometry (UPLC-ESI-MS/MS). A grand total of 558 metabolites were [...] Read more.
This study aims to identify the differences in metabolites between Fructus Chebulae (FC) and Fructus Terminaliae Billericae (FTB). Untargeted metabolomics was used to analyze differentially expressed metabolites (DEMs) with ultra-performance liquid chromatography–electrospray ionization–tandem mass spectrometry (UPLC-ESI-MS/MS). A grand total of 558 metabolites were detected, with 155 in positive ion mode and 403 in negative ion mode. Further differential analysis yielded 110 and 87 significantly different metabolites, which were mainly polyphenols, flavonoids, terpenoids, and alkaloids. Analysis of KEGG data showed that differentially expressed metabolites (DEMs) in both positive and negative ion modes were found to be enriched in 5 and 18 metabolic pathways, respectively, with metabolic pathways being the most enriched among them. In sum, this study reveals the differential metabolic profiles of FC and FTB and provides support for their further applications in traditional Chinese medicine. Full article
(This article belongs to the Special Issue Advances in Food Metabolomics)
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