Reaction Mechanism of the Ferredoxin–Ferredoxin NAD(P)+/H Oxidoreductase System
A special issue of Antioxidants (ISSN 2076-3921).
Deadline for manuscript submissions: closed (15 December 2021) | Viewed by 15952
Special Issue Editors
Interests: ferredoxin-NAD(P)+ oxidoreductase; iron–sulfur protein; flavodoxin; cyctochrome c; phototrophic bacteria; iron–sulfur-type photoreaction center
Interests: flavoenzyme catalysis; oxidative stress; bioreductive activation; redox active drugs; quinones; aromatic nitrocompounds and N-oxides; polyphenols
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Ferredoxin (Fd) and flavodoxin (Fld) function as an electron mediator in biosynthetic/biodegrading processes such as carbon dioxide assimilation, nitrogen assimilation, cytochrome P450-dependent oxygenation, and S-adenosylmethionine-dependent reactions. Fd and Fld are also involved in the generation and scavenging of reactive oxygen species as the nature of a low redox potential electron mediator. In many living organisms, ferredoxin-NAD(P)+ oxidoreductase (FNR) promotes Fd/Fld reduction/oxidation reactions in an NAD(P)+/H-dependent manner. Recent progress in genomics, proteomics, and metabolomics, as well as research with biochemical, biophysical, and physiological approaches to wide-ranging organisms, have expanded the versatility of the roles and reaction mechanisms of FNR and Fd-FNR systems.
This Special Issue invites research findings and reviews of recent works which share updates on and enrich our knowledge around FNRs, its isozymes, such as adrenodoxin reductase, putidaredoxin reductase, and its homologues, and Fd/Fld–FNR systems in bacteria, archaea, protozoa, plants, and vertebrate. The issue targets research on a molecular to cellular level: reaction intermediate, electron/hydride transfer reactions, substrate recognition, structure–function relation, supramolecular assembly, response to environmental and drug stresses utilizing spectroscopic, kinetic, and structural analyses, computational science, genomics, proteomics, and metabolomics approaches. We believe that this Special Issue, “Reaction Mechanism of a Ferredoxin–Ferredoxin NAD(P)+/H Oxidoreductase System”, will help to highlight the most recent advances on all aspects of Fd–FNR systems.
We look forward to your contribution.
Dr. Daisuke Seo
Prof. Dr. Narimantas K. Cenas
Guest Editors
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Keywords
- Iron–sulfur protein
- Flavodoxin
- Adrenodoxin
- Putidaredoxin
- Flavin
- NADH
- NADPH
- Oxidoreductase
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