Special Issue "Biofilm Infection"
A special issue of Antibiotics (ISSN 2079-6382).
Deadline for manuscript submissions: closed (31 October 2015) | Viewed by 26897
Interests: Candida biofilms; antibiofilm; microbiome
Special Issues, Collections and Topics in MDPI journals
Interests: the role of biofilms in human infection; treatment of infection in immunocompromised patients; the role of the built environment in the transmission of healthcare associated infection
In clinical microbiology when chemotherapeutic management fails, there is a tendency to focus on defined antimicrobial resistance mechanisms related to inheritable genetic traits. However, it is increasingly apparent that treatment failure may be related to microbial biofilms, which are an increasingly important clinical problem. Microbial biofilms are complex and heterogeneous structures encased within extrapolymeric matrix, and cells encased within, exhibit dramatic change in their resistance profiles compared to free-floating counterparts by adapting to their environment and changing their phenotypic and genotypic characteristics accordingly.
While our understanding of the basic biology of microbial biofilms has greatly improved, we still face challenges in developing effective clinical management strategies. Some key areas still require exploration:
- How do we diagnose biofilm related infections more effectively?
- What is the impact of biofilms on clinical outcomes?
- How do we manage polymicrobial biofilm infection?
- Are there methods to augment existing chemotherapeutic strategies?
- Does sub-optimal treatment of biofilms make them more pathogenic?
"Antibiotics" will publish a special issue focusing on the clinical management of biofilm related infections. It is our pleasure to invite submissions of high quality research based papers related to the questions mentioned above.
Prof. Dr. Gordon Ramage
Prof. Dr. Craig Williams
Dr. Karen Smith
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.