Botanicals and Antibiotic Resistance

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "The Global Need for Effective Antibiotics".

Deadline for manuscript submissions: closed (31 July 2021) | Viewed by 8845

Special Issue Editor


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Guest Editor
Department of Food and Human Nutritional Sciences, Faculty of Agricultural and Food Sciences, University of Manitoba Winnipeg, Winnipeg, MB R3T 2N2, Canada
Interests: edible oils; polyphenols; gums; nutraceuticals
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Special Issue Information

Dear Colleagues,

The overuse of antibiotics has resulted in microbial infections that are resistant to antibiotics. As a result, antibacterial drugs have now become less effective or totally ineffective. The increase in multidrug-resistant bacteria and the lack of any new antibiotics by pharmaceutical companies have led to a global health crisis responsible for millions of deaths annually. One of the strategies for overcoming microbial resistance to antibiotics, however, is to combine them with natural phytochemicals capable of restoring their efficacy. Achieving this requires a clear understanding of the mechanisms by which bacteria develop antibiotic resistance and how phytochemicals can help to overcome their resistance. This issue will discuss some of the mechanisms of antibiotic resistance as well as the potential benefits of a select group of botanicals in restoring antibiotic potency.

Professor N.A. Michael Eskin
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Botanicals
  • Bacteria
  • Antibiotic resistance
  • Mechanisms
  • Bioactive synergism

Published Papers (1 paper)

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Review

33 pages, 6608 KiB  
Review
Phytochemicals: A Promising Weapon in the Arsenal against Antibiotic-Resistant Bacteria
by Bahman Khameneh, N. A. Michael Eskin, Milad Iranshahy and Bibi Sedigheh Fazly Bazzaz
Antibiotics 2021, 10(9), 1044; https://doi.org/10.3390/antibiotics10091044 - 26 Aug 2021
Cited by 39 | Viewed by 8113
Abstract
The extensive usage of antibiotics and the rapid emergence of antimicrobial-resistant microbes (AMR) are becoming important global public health issues. Many solutions to these problems have been proposed, including developing alternative compounds with antimicrobial activities, managing existing antimicrobials, and rapidly detecting AMR pathogens. [...] Read more.
The extensive usage of antibiotics and the rapid emergence of antimicrobial-resistant microbes (AMR) are becoming important global public health issues. Many solutions to these problems have been proposed, including developing alternative compounds with antimicrobial activities, managing existing antimicrobials, and rapidly detecting AMR pathogens. Among all of them, employing alternative compounds such as phytochemicals alone or in combination with other antibacterial agents appears to be both an effective and safe strategy for battling against these pathogens. The present review summarizes the scientific evidence on the biochemical, pharmacological, and clinical aspects of phytochemicals used to treat microbial pathogenesis. A wide range of commercial products are currently available on the market. Their well-documented clinical efficacy suggests that phytomedicines are valuable sources of new types of antimicrobial agents for future use. Innovative approaches and methodologies for identifying plant-derived products effective against AMR are also proposed in this review. Full article
(This article belongs to the Special Issue Botanicals and Antibiotic Resistance)
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