Antimicrobial Agents: Present Situation and Prospects for the Future
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Novel Antimicrobial Agents".
Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 3580
Special Issue Editor
Interests: biofilms; metallotherapeutic compounds; implant-associated infections; novel antimicrobial agents; reactive oxygen species; reactive nitrogen species; carbon monoxide and CO-releasing molecules
Special Issue Information
Dear Colleagues,
Over recent decades, there has been a significant increase in microbial infections that display multidrug resistance, leading to a concomitant increase in mortality rates. As last-line antimicrobial treatments increasingly fail, antimicrobial resistance is becoming an ever-increasing global threat to public health.
Metal complexes have demonstrated antimicrobial activity throughout recorded history; however, due to the wide range of effective conventional antibiotics developed for use since the early 1940s, these leads are mostly underdeveloped. With the current growing antibiotic resistance crisis and lack of development of new antibiotics, the use of metals as antimicrobials has gained popularity in recent years, raising the possibility that metal complexes can bring new life to antimicrobial drug discovery.
This Special Issue aims to gather papers describing the current use and future development of metal complexes as antimicrobial agents that are active against bacteria, fungi and viruses. We are also welcoming papers describing the discovery of novel targets and mechanisms of action and resistance, as well as the use of omic and bioinformatic approaches for the development of new metal-based antimicrobial leads.
In this Special Issue, original research articles and reviews are welcome.
I look forward to receiving your contributions.
Dr. Samantha McLeanGuest Editor
Manuscript Submission Information
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Keywords
- metals
- novel antimicrobials
- infection
- drug discovery
- nanoparticles
- antimicrobial resistance
- drug delivery
- adjuvants
- synergy
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