Nanotechnology for Antimicrobials in Medicine and Agriculture, 2nd Volume

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antimicrobial Materials and Surfaces".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 3659

Special Issue Editors


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Guest Editor
1. Scientific and Technological Bioresource Nucleus, Universidad de La Frontera, Temuco 4811230, Chile
2. Centro de Excelencia en Inv. Biotecnológica Aplicada al Medioambiente (CIBAMA), Universidad de La Frontera, Temuco 4811230, Chile
Interests: nanotechnology; environmental microbiology; environmental biotechnology
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Center for Natural and Human Sciences (CCNH), Federal University of ABC (UFABC), Av. dos Estados, 5001-Bangú, Santo André 09210-580, SP, Brazil
Interests: nanomaterials; biomaterials; drug delivery; nitric oxide; cytotoxicity
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Instituto de Química San Luis (INQUISAL), Departamento de Química, Universidad Nacional de San Luis, CONICET, Chacabuco 917, San Luis D5700BWS, Argentina
Interests: nanotechnology; microfluidic device; biosensors; immunosensors; electrochemistry
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Guest Editor
Department of Horticulture, Universidad Autónoma Agraria Antonio Narro, Saltillo 25315, Mexico
Interests: nanotechnology; plant biostimulation; biostimulants; biofortification; plant stress
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Special Issue Information

Dear Colleagues,

The first volume of the Special Issue “Nanotechnology for Antimicrobials in Medicine and Agriculture” was published in 2022. It is a successful issue with 14 published papers and has encouraged us to open a second volume on the same topic. We are honored to invite Dr. Martín A. Fernández-Baldo and Dr. Adalberto Benavides-Mendoza to join us to lead this Special Issue together.

The key motivation behind this Special Issue on “Nanotechnology for Antimicrobials” is to collect knowledge regarding the research and development of nanomaterials that open new possibilities for the effective treatment of diseases from a medical or agricultural point of view. The MDPI journal Antibiotics and the editors of this Special Issue invite you to submit review articles and original research papers that provide a broad overview of nanomaterials for the treatment of viral, fungal, or bacterial diseases in humans or in crops. Moreover, manuscripts related to nanomaterials used as an additive in textiles, medical devices, or personal protective equipment to prevent infections are also welcome.

Dr. Gonzalo Tortella
Prof. Dr. Amedea B. Seabra
Dr. Martín A. Fernández-Baldo
Dr. Adalberto Benavides-Mendoza
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanomaterials
  • nanoparticles
  • human health
  • crop protection
  • bacterial
  • fungi
  • virus

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Published Papers (2 papers)

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Research

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23 pages, 8093 KiB  
Article
Unraveling the Complex Interactions: Machine Learning Approaches to Predict Bacterial Survival against ZnO and Lanthanum-Doped ZnO Nanoparticles
by Diego E. Navarro-López, Yocanxóchitl Perfecto-Avalos, Araceli Zavala, Marco A. de Luna, Araceli Sanchez-Martinez, Oscar Ceballos-Sanchez, Naveen Tiwari, Edgar R. López-Mena and Gildardo Sanchez-Ante
Antibiotics 2024, 13(3), 220; https://doi.org/10.3390/antibiotics13030220 - 27 Feb 2024
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Abstract
The rise in antibiotic-resistant bacteria is a global health challenge. Due to their unique properties, metal oxide nanoparticles show promise in addressing this issue. However, optimizing these properties requires a deep understanding of complex interactions. This study incorporated data-driven machine learning to predict [...] Read more.
The rise in antibiotic-resistant bacteria is a global health challenge. Due to their unique properties, metal oxide nanoparticles show promise in addressing this issue. However, optimizing these properties requires a deep understanding of complex interactions. This study incorporated data-driven machine learning to predict bacterial survival against lanthanum-doped ZnO nanoparticles. The effect of incorporation of lanthanum ions on ZnO was analyzed. Even with high lanthanum concentration, no significant variations in structural, morphological, and optical properties were observed. The antibacterial activity of La-doped ZnO nanoparticles against Gram-positive and Gram-negative bacteria was qualitatively and quantitatively evaluated. Nanoparticles induce 60%, 95%, and 55% bacterial death against Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus, respectively. Algorithms such as Multilayer Perceptron, K-Nearest Neighbors, Gradient Boosting, and Extremely Random Trees were used to predict the bacterial survival percentage. Extremely Random Trees performed the best among these models with 95.08% accuracy. A feature relevance analysis extracted the most significant attributes to predict the bacterial survival percentage. Lanthanum content and particle size were irrelevant, despite what can be assumed. This approach offers a promising avenue for developing effective and tailored strategies to reduce the time and cost of developing antimicrobial nanoparticles. Full article
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Review

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26 pages, 6296 KiB  
Review
Advances in Nanomaterials and Composites Based on Mesoporous Materials as Antimicrobial Agents: Relevant Applications in Human Health
by Germán E. Gomez, Mariana Hamer, Matías D. Regiart, Gonzalo R. Tortella, Amedea B. Seabra, Galo J. A. A. Soler Illia and Martín A. Fernández-Baldo
Antibiotics 2024, 13(2), 173; https://doi.org/10.3390/antibiotics13020173 - 09 Feb 2024
Cited by 1 | Viewed by 1452
Abstract
Nanotechnology has emerged as a cornerstone in contemporary research, marked by the advent of advanced technologies aimed at nanoengineering materials with diverse applications, particularly to address challenges in human health. Among these challenges, antimicrobial resistance (AMR) has risen as a significant and pressing [...] Read more.
Nanotechnology has emerged as a cornerstone in contemporary research, marked by the advent of advanced technologies aimed at nanoengineering materials with diverse applications, particularly to address challenges in human health. Among these challenges, antimicrobial resistance (AMR) has risen as a significant and pressing threat to public health, creating obstacles in preventing and treating persistent diseases. Despite efforts in recent decades to combat AMR, global trends indicate an ongoing and concerning increase in AMR. The primary contributors to the escalation of AMR are the misuse and overuse of various antimicrobial agents in healthcare settings. This has led to severe consequences not only in terms of compromised treatment outcomes but also in terms of substantial financial burdens. The economic impact of AMR is reflected in skyrocketing healthcare costs attributed to heightened hospital admissions and increased drug usage. To address this critical issue, it is imperative to implement effective strategies for antimicrobial therapies. This comprehensive review will explore the latest scientific breakthroughs within the metal–organic frameworks and the use of mesoporous metallic oxide derivates as antimicrobial agents. We will explore their biomedical applications in human health, shedding light on promising avenues for combating AMR. Finally, we will conclude the current state of research and offer perspectives on the future development of these nanomaterials in the ongoing battle against AMR. Full article
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