Omics in Animal Reproduction

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal Reproduction".

Deadline for manuscript submissions: closed (31 May 2021) | Viewed by 3305

Special Issue Editors


E-Mail Website
Guest Editor
School of Agriculture and Food Sciences, University of Queensland, St Lucia, QLD, Australia
Interests: production animal reproduction; andrology; sperm; semen; proteomics; metabolomics lipidomics

E-Mail Website
Guest Editor
School of Veterinary Science, University of Queensland, Brisbane, QLD, Australia
Interests: production animal reproduction; andrology; sperm; semen; proteomics; metabolomics lipidomics

Special Issue Information

Dear Colleagues,

Advances in omics and multi-omics technologies over the past decade have greatly enhanced research capabilities into biomedical applications, including reproductive processes. The use of a high-level multidimensional approach for systems biology and associated bioinformatics enables a holistic screen of several mechanisms and integrates genomics, transcriptomics, proteomics, lipidomics, metabolomics, cellomics, and other -omics for a more comprehensive understanding of biological systems. The interrelationships of the male and female system in addition to the interactions of the gametes for fertilization to then form a new being is indeed a complex and unique biological system with considerable variations across organisms. This Special Issue explores applications and take-up of systems biology approaches into animal reproduction, with special emphasis on the gamete interactions that enable fertilization and advanced methodologies to enhance assisted reproductive technologies.

Dr. Nana Satake
Dr. Gry Boe-Hansen
Guest Editors

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Keywords

  • multi-omics
  • animal reproduction
  • systems biology

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Published Papers (1 paper)

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Research

12 pages, 3052 KiB  
Article
Metabolomic Analysis and Identification of Sperm Freezability-Related Metabolites in Boar Seminal Plasma
by Yuting Zhang, Hanlin Liang, Yan Liu, Meng Zhao, Qianqian Xu, Zhonghua Liu and Xiaogang Weng
Animals 2021, 11(7), 1939; https://doi.org/10.3390/ani11071939 - 29 Jun 2021
Cited by 14 | Viewed by 2804
Abstract
Some potential markers of boar sperm freezability have been found in spermatozoa, but little attention has been paid to seminal plasma. The seminal plasma is composed of secretions from the testis, epididymis, and accessory sex glands. The exposure of spermatozoa to small molecules [...] Read more.
Some potential markers of boar sperm freezability have been found in spermatozoa, but little attention has been paid to seminal plasma. The seminal plasma is composed of secretions from the testis, epididymis, and accessory sex glands. The exposure of spermatozoa to small molecules such as metabolites can affect sperm function. However, details and significance of the seminal plasma metabolome related to boar sperm freezability are unknown. Therefore, the main aim of this study was to explore the differences in the metabolic level of seminal plasma between boars with differential freezability and to explore the candidate biomarkers of semen freezability. A total of 953 metabolites were identified in boar semen plasma by UHPLC-qTOF-MS analysis, and 50 metabolites showed significant change between the GFE group and PFE group. Further, twelve metabolites were subjected to metabolic target analysis, and three metabolites (D-aspartic acid, N-acetyl-L-glutamate (NAG), and inosine) showed differences. In conclusion, there is significant difference in the metabolome of seminal plasma between GFE and PFE individuals. D-aspartic acid, NAG, and inosine in seminal plasma may be potential markers for assessing sperm cryopreservation resistance in boars. Full article
(This article belongs to the Special Issue Omics in Animal Reproduction)
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