Feeding Strategies to Improve the Health or Development of Piglets

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal Nutrition".

Deadline for manuscript submissions: 31 August 2026 | Viewed by 2298

Special Issue Editors


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Guest Editor
Institute of Animal Science and Veterinary, Tianjin Academy of Agricultural Sciences, Tianjin, China
Interests: pig and poultry nutrition; intestinal health; sow–piglets nutrition transfer; feed additives; gut microbiota
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Guest Editor
Key Laboratory for Quality Regulation of Livestock and Poultry Products of Hunan Province, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China
Interests: maternal and offspring nutrition; intestinal development and health; precision feeding techniques
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

It is well accepted that the early-life phase of piglets is a pivotal window for shaping their health, growth trajectory, and resilience to stressors, particularly during the challenging transition from suckling and weaning. This Special Issue focuses on cutting-edge nutritional interventions designed to address critical issues such as gut dysbiosis, immune immaturity, and metabolic disruptions. Contributions will highlight advances in functional feed additives (e.g., postbiotics, phytogenics, enzymes, etc.), precision-formulated diets, and strategies to enhance nutrient digestibility and health status of piglets. Emphasis is placed on the interplay between maternal dietary programming and offspring outcomes, as well as sustainable approaches to reduce reliance on antibiotics. By bridging foundational research with practical applications, this collection aims to empower producers and researchers to optimize piglet health, mitigate post-weaning morbidity, and support the global shift toward ethical, efficient swine production systems.

In this Special Issue, original research articles and reviews are welcome. Research areas include the following:

  1. Gestation and lactation nutrition interventions on piglets’ development;
  2. Functional feed additives or strategies to enhance nutrient digestibility or health status of piglets;
  3. Sustainable approaches to reduce reliance on antibiotics;
  4. Interventions on post-weaning diarrhea;
  5. Environmental stressors (heat stress, poor sanitation, overcrowding, etc.) on the health status of piglets
  6. Nutritional imbalances, such as deficiencies in vitamins (A-, D-, E-, and B-complex), minerals (iron and selenium), or amino acids, leading to anemia and poor immunity;
  7. Precise feeding and gut microbiome manipulation in the early stages of life.

We look forward to receiving your contributions.

Dr. Chunyan Xie
Prof. Dr. Jing Wang
Guest Editors

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Keywords

  • maternal programming
  • weaning transition
  • feed additives
  • immune development
  • antioxidant capacity
  • nutrient digestibility
  • suckling piglet nutrition
  • precision nutrition
  • antimicrobial agent

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Published Papers (2 papers)

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Research

12 pages, 227 KB  
Article
Supplementing 25-Hydroxy-Vitamin D3 to Sows Enhances Milk and Blood Parameters, with Extended Benefits to Their Offspring
by Shanmugam Sureshkumar, Md Raihanul Hoque and In Ho Kim
Animals 2025, 15(22), 3264; https://doi.org/10.3390/ani15223264 - 11 Nov 2025
Viewed by 607
Abstract
The objective of this study was to evaluate the effects of 25-hydroxy-vitamin D3 (25OHD3) supplementation on reproductive performance, nutrient digestibility, lameness score, milk composition, and blood profiles in sows, as well as the performance and blood profiles of their offspring. [...] Read more.
The objective of this study was to evaluate the effects of 25-hydroxy-vitamin D3 (25OHD3) supplementation on reproductive performance, nutrient digestibility, lameness score, milk composition, and blood profiles in sows, as well as the performance and blood profiles of their offspring. From day 110 of gestation to 21 days of weaning, a total of 30 multiparous sows (Landrace × Yorkshire) were randomly assigned to one of three dietary treatments, with ten sows per treatment. The dietary treatments were: (1) CON, basal diet; (2) TRT1, CON diet plus 1114 IU 25OHD3/kg (13.92 µg 25OHD3/kg feed); and (3) TRT2, CON diet plus 2227 IU 25OHD3/kg (27.84 µg 25OHD3/kg feed). The reproduction performance and nutrient digestibility of sows were not affected by 25OHD3 supplementation. However, the inclusion of graded levels of 25OHD3 in the sow diet had significantly reduced their farrowing time (p < 0.001) compared to those fed the CON diet. Also, sows fed 25OHD3 produced significantly higher (p < 0.05) number of piglets compared to the CON group. Piglets from supplemented sows exhibited greater (p < 0.05) average daily gain and weaning body weight. Moreover, colostrum protein content was higher (p < 0.05) in sows fed 25OHD3 compared with the CON group. Similarly, the concentration of 25OHD3 in colostrum and milk at weaning was markedly (p < 0.001) elevated. Furthermore, serum 25OHD3 levels were significantly higher (p < 0.05) in both sows and piglets, and piglet serum immunoglobulin G (IgG) concentrations were also elevated (p < 0.05) in the supplemented groups. In summary, dietary 25OHD3 in the sow diet not only improves their reproductive performance and milk quality but also enhances piglet growth, immunity, and overall vitality, suggesting that 25OHD3 is a valuable nutritional strategy for optimizing sow productivity and promoting healthier offspring. Full article
(This article belongs to the Special Issue Feeding Strategies to Improve the Health or Development of Piglets)
18 pages, 1192 KB  
Article
Modulation of Milk Source Differences on Immunity, Nutritional Physiology and Intestinal Microbiota in Neonatal Piglets
by Junhong Liu, Miaomiao Bai, Shanshan Wang, Yihui Zhang, Changfeng Peng, Yirui Shao, Xia Xiong, Yueyao Xing and Hongnan Liu
Animals 2025, 15(21), 3104; https://doi.org/10.3390/ani15213104 - 25 Oct 2025
Viewed by 1394
Abstract
Milk sources directly influence digestion, absorption, and overall nutrient utilization during early infant nutrition. Goat milk features a nutritional composition and digestive properties that are more similar to human breast milk. This study aimed to investigate the effects of different milk sources on [...] Read more.
Milk sources directly influence digestion, absorption, and overall nutrient utilization during early infant nutrition. Goat milk features a nutritional composition and digestive properties that are more similar to human breast milk. This study aimed to investigate the effects of different milk sources on the immunity, amino acid and fatty acid metabolism, and intestinal microbiota in neonatal piglets. Sixteen 7-day-old suckling piglets were randomly allocated into two groups (eight replicates/group, one piglet/replicate) and fed with standard formula milk powder (CON) and goat milk formula powder (GMF). The formal experiment lasted for 14 days. Results showed that compared with the CON group, the GMF group showed a significant increase (p < 0.05) in the final weight, the serum levels of immunoglobulin A (IgA), IgG, IgM and C-reactive protein (CRP4), and intestinal trypsin content. Additionally, the GMF group had higher (p < 0.05) serum essential and non-essential amino acid and fatty acid levels, and had trends toward upregulation (0.05 < p < 0.1) in hepatic mRNA expression of spermine N1-acetyltransferase 1 (SAT1), duodenal peptide transporter 1 (PePT1), and jejunal cationic amino acid transporter 1 (CAT1). Microbiome sequencing revealed that GMF enhanced intestinal microbial richness and diversity and increased concentrations of acetic and propionic acids (p < 0.05). In conclusion, GMF suggests a potential improvement in the growth performance by enhancing immunity, amino acid and fatty acid metabolism and optimizing intestinal microbiota composition in neonatal piglets. These findings further support the favorable nutritional properties and tolerability of GMF in early-life nutrition. Full article
(This article belongs to the Special Issue Feeding Strategies to Improve the Health or Development of Piglets)
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