Special Issues

AI publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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AI for Good
edited by Manolya Kavakli-Thorne
submission deadline 30 May 2026 | Viewed by 1216 | Submission Open
Keywords: artificial intelligence; machine learning; mixed reality; disruptive technologies; wellbeing
Artificial Intelligence in the Integration of Information Systems: Current Trends and Future Opportunities submission deadline 5 Jun 2026 | Viewed by 2941 | Submission Open
Keywords: artificial intelligence; system integration; sustainable information systems; smart cities; green AI; circular economy; ESG analytics; data transparency
The Future of Robotics: AI Algorithms, Ethics, and Real-World Applications
edited by , Nikolaos Vasilopoulos and Paraskevas Diamantatos
submission deadline 15 Jun 2026 | 2 articles | Viewed by 2992 | Submission Open
Keywords: artificial intelligence; automation systems; machine learning; intelligent control; autonomous robotics; computer vision; sensor fusion; digital twins; predictive maintenance; human-machine interaction
(This special issue belongs to the Section AI in Autonomous Systems)
Intelligent Defenses: The Role of AI in Strengthening Information Security submission deadline 26 Jun 2026 | 2 articles | Viewed by 4783 | Submission Open
Keywords: artificial intelligence (AI); cybersecurity; intelligent defense systems; machine learning; deep learning; intrusion detection systems (IDS); threat intelligence; anomaly detection; malware detection; behavioral analytics  ; automated incident response; adversarial AI; cyber threat prediction; security automation; data privacy; ethical AI; real-time threat detection; AI-driven cyber defense; security analytics; digital infrastructure protection
(This special issue belongs to the Section AI in Autonomous Systems)
Large Language Models and Retrieval-Augmented Generation in Natural Language Processing, Human–Robot Interaction and Quantum Computing
edited by
submission deadline 30 Jun 2026 | 1 articles | Viewed by 10068 | Submission Open
Keywords: large language models; retrieval-augmented generation; natural language processing; knowledge graphs; knowledge grounding; human– robot interaction; agentic computing; vision– language– action models; quantum computing; quantum-enhanced information retrieval; evaluation methodologies; reliability assessment; explainability; hallucination mitigation; vector search optimization; quantum code generation; multi-modal RAG
(This special issue belongs to the Section AI Systems: Theory and Applications)
Human-Computer Interaction and Human-Centered AI submission deadline 30 Jun 2026 | 2 articles | Viewed by 2531 | Submission Open
Keywords: human-centered AI; human– computer interaction; explainable AI; responsible AI; trust in AI; mental models; adaptive systems; user experience; fairness and ethics; human– AI collaboration; interaction design; cognitive models; value-sensitive design; behavioral responses to AI
(This special issue belongs to the Section AI Systems: Theory and Applications)
Measuring What Matters: AI and the Future of Fair Assessment
edited by
submission deadline 1 Jul 2026 | Viewed by 762 | Submission Open
Keywords: artificial intelligence; educational assessment; fairness; equity in education; algorithmic bias; adaptive testing; ethical AI; inclusive assessment
(This special issue belongs to the Section AI Systems: Theory and Applications)
Transforming Biomedical Innovation with Artificial Intelligence submission deadline 15 Jul 2026 | 5 articles | Viewed by 15905 | Submission Open
Keywords: artificial intelligence in biomedicine; machine learning for health and disease; deep learning for biomedical innovation; medical imaging and computational diagnostics; digital health technologies and wearable AI devices; bioinformatics and computational biology; clinical decision support and predictive analytics; explainable; robust; and ethical AI in healthcare; multimodal biomedical data fusion; AI for drug discovery and personalized therapeutics
The Digital Immune System: AI-Driven Detection and Mitigation of Online Harms
edited by , and Hisami Suzuki
submission deadline 15 Jul 2026 | 1 articles | Viewed by 5032 | Submission Open
Keywords: disinformation/misinformation/malinformation; hate speech/toxic language/cyberbullying; propaganda analysis; adversarial learning/adversarial defense; causal inference/explainable AI (XAI)/interpretability; content moderation/counter-narrative generation; AI trust and safety
Innovative Artificial Intelligent Solutions for a Sustainable Future
edited by
submission deadline 25 Jul 2026 | Viewed by 593 | Submission Open
Keywords: machine learning; deep learning; natural language processing; computer vision; sustainable cultural education; digital cultural heritage preservation; artistic innovation; social governance; collaborative development
Development of Artificial Intelligence and Computational Thinking: Future Directions, Opportunities, and Challenges submission deadline 31 Jul 2026 | 5 articles | Viewed by 21016 | Submission Open
Keywords: Artificial Intelligence (AI); computational thinking; machine learning; data science; algorithms; educational technology; ethical  AI; automation; problem solving; future trends; digital literacy; algorithmic bias; educational innovation; society and technology; innovation in education
The Use of Artificial Intelligence in Business: Innovations, Applications and Impacts
edited by , Hossam Ali-Hassan and
submission deadline 31 Jul 2026 | 2 articles | Viewed by 5416 | Submission Open
Keywords: transformation; smart business solutions; predictive innovation; AI-driven strategy; machine learning insights; automated intelligence; generative AI applications; future of work; ethical AI in business; digital decision-making; intelligent enterprise
(This special issue belongs to the Section AI Systems: Theory and Applications)
AI for Industrial Operation and Maintenance: Recognition Challenges with Limited Data Condition submission deadline 31 Jul 2026 | 3 articles | Viewed by 3904 | Submission Open
Keywords: industrial artificial intelligence; predictive maintenance; few-shot learning; fault diagnosis; data-efficient learning; transfer learning; digital twin; uncertainty quantification
AI Applications in Emergency Response and Fire Safety
edited by Yoon J. Ko and Ankit Agrawal
submission deadline 31 Jul 2026 | 1 articles | Viewed by 2914 | Submission Open
Keywords: predictive analytics; enhanced detection; situational awareness; and hazard scoping; automating data processes; optimizing response/firefighting/evacuation strategies; supporting/improving decision-making; data management and analysis for risk assessment; smart emergency/fire modeling
(This special issue belongs to the Section AI in Autonomous Systems)
Sensing the Future: IOT-AI Synergy for Climate Action
edited by
submission deadline 31 Jul 2026 | 1 articles | Viewed by 1675 | Submission Open
Keywords: IoT for climate action; AI and water resilience; flood forecasting and management; game-theoretic water allocation; water-energy-food nexus; telematics and water informatics; remote sensing and hydrology; deep learning for rainfall prediction; digital twin of water systems
(This special issue belongs to the Section AI Systems: Theory and Applications)
Intelligent Cloud–Edge Networking: Innovations for Next-Gen Applications
edited by
submission deadline 7 Aug 2026 | 1 articles | Viewed by 1298 | Submission Open
Keywords: cloud computing; edge computing; cloud– edge systems; network orchestration; distributed machine learning; scalable network architectures; network slicing; network security and privacy; next-generation applications; autonomous systems
(This special issue belongs to the Section AI in Autonomous Systems)
AI-Driven Multimodal Interfaces in XR: Enhancing Human–Computer Interaction submission deadline 14 Aug 2026 | 1 articles | Viewed by 4437 | Submission Open
Keywords: multimodal interfaces; extended reality (XR); artificial intelligence (AI); human– computer interaction (HCI); adaptive systems
(This special issue belongs to the Section AI in Autonomous Systems)
Advances in Post-Quantum Security
edited by Ajay Kaushik and
submission deadline 15 Aug 2026 | Viewed by 181 | Submission Open
Keywords: artificial intelligence for security; cryptographic protocols; cyber security; internet of things security; post-quantum cryptography; quantum-resistant security; secure 5G and 6G networks; applied artificial intelligence
Generative AI Applications for Power Systems submission deadline 25 Aug 2026 | 1 articles | Viewed by 938 | Submission Open
Keywords: AI; generative AI; GANs; VAEs; transformers
(This special issue belongs to the Section AI in Autonomous Systems)
Leveraging Simulation and Deep Learning for Enhanced Health and Safety
edited by and
submission deadline 28 Aug 2026 | 3 articles | Viewed by 6401 | Submission Open
Keywords: deep learning; simulation-based modeling; AI safety; explainable AI (XAI); risk simulation; causal inference; computer vision; digital twins; safety-critical systems; property prediction
(This special issue belongs to the Section AI Systems: Theory and Applications)
Explainable and Trustworthy AI in Health and Biology: Enabling Transparent and Actionable Decision-Making
edited by Ahmed Salih
submission deadline 31 Aug 2026 | 3 articles | Viewed by 5498 | Submission Open
Keywords: explainable AI; trustworthy AI; model interpretability; responsible AI
(This special issue belongs to the Section Medical & Healthcare AI)
Application of Artificial Intelligence on Structures Subjected to Natural Hazards
edited by , Juan Bojórquez and
submission deadline 31 Aug 2026 | 2 articles | Viewed by 5486 | Submission Open
Keywords: earthquake engineering; seismic hazard; wind hazard; neural networks; metaheuristic techniques
Integrating Large Language Models into Robotic Autonomy submission deadline 31 Aug 2026 | 1 articles | Viewed by 1332 | Submission Open
Keywords: LLMs in locomotion control; LLMs in navigation and semantic planning; LLMs in physical interaction and manipulation; voice-based control and communication; sensor-grounded perception; learning; real-time decision-making through voice and text commands; robot-to-human/robot-to-robot interaction; structured reasoning through multi-level representations
(This special issue belongs to the Section AI Systems: Theory and Applications)
Advances in Artificial Intelligence and Emerging Machine Learning Applications
edited by Naveed Ilyas and Taqi Abrar
submission deadline 31 Aug 2026 | 1 articles | Viewed by 1189 | Submission Open
Keywords: artificial intelligence; machine learning; deep learning; transformer networks; generative models; computer vision; medical image analysis; explainable AI; interdisciplinary applications; diffusion models
Next-Generation Medical Imaging AI: Deep Learning Computer Vision with Multi-Task and Continual Learning
edited by , Tahir Mahmood and
submission deadline 31 Aug 2026 | Viewed by 521 | Submission Open
Keywords: medical imaging; computer vision; deep learning; multi-task learning; continual learning; medical image segmentation; medical image classification; attention mechanisms; vision transformers; self-supervised learning; weakly supervised learning; domain adaptation; explainable AI; uncertainty estimation; clinical decision support
(This special issue belongs to the Section Medical & Healthcare AI)
Smart Educational Technologies: Integrating AI, Robotics, and AR for 21st Century Learning
edited by and
submission deadline 31 Aug 2026 | Viewed by 492 | Submission Open
Keywords: artificial intelligence in education; technology-enhanced learning; computational thinking; educational robotics; learning analytics; personalized learning; augmented reality (AR) in education
Multi-Agent Modal Computing: Synergy, Scalability and Satellite-Earth Collaboration
edited by , and
submission deadline 31 Aug 2026 | Viewed by 439 | Submission Open
Keywords: multi-agent systems; multimodal learning; satellite computing; knowledge graph; edge AI; federated learning; remote sensing; distributed inference
Machine Learning-Augmented Optimization Methods for Energy and Infrastructure Systems
edited by , Chen Yang and Haoran Niu
submission deadline 31 Aug 2026 | Viewed by 259 | Submission Open
Keywords: machine learning-augmented optimization; learning-augmented algorithms; hybrid AI-optimization methods; energy system optimization; reinforcement learning for planning; critical infrastructure planning; robust and stochastic optimization; spatial and network optimization; digital twins for infrastructure systems; explainable AI for decision support
(This special issue belongs to the Section AI Systems: Theory and Applications)
Adaptive Control and Cognitive Architectures: Bridging Cybernetics, Neuroscience, and AI
edited by
submission deadline 18 Sep 2026 | Viewed by 384 | Submission Open
Keywords: adaptive control; cognitive architectures; cybernetics; neuroscience; artificial intelligence
(This special issue belongs to the Section AI Systems: Theory and Applications)
Responsible AI: Alignment, Decentralization, and Optimization in Multi-Agent Systems Across Dynamic Environments
edited by Chansoo Kim
submission deadline 23 Sep 2026 | 2 articles | Viewed by 5381 | Submission Open
Keywords: multi-agent systems; AI alignment and trustworthiness; AI ethical and social implications (ethical and societal dimensions); alignment with human values; decentralized and federated learning; optimization and AI; reinforcement and evolutionary learning; causal reasoning; robustness and adaptivity; dynamic environments; real-world AI applications and various applications such as physical AI (robotics); energy and battery; and finance and economics
(This special issue belongs to the Section AI Systems: Theory and Applications)
Large Language Models and Autonomous Agents for Semantic Web, Search, and Recommendations
edited by and
submission deadline 25 Sep 2026 | Viewed by 290 | Submission Open
Keywords: large language models; autonomous AI agents; semantic web; information retrieval; intelligent search systems; recommendation systems; foundation models; knowledge graphs; semantic representation learning; retrieval-augmented generation
(This special issue belongs to the Section AI Systems: Theory and Applications)
Artificial Intelligence for Next-Generation Adaptive Control Systems and Robotics submission deadline 28 Sep 2026 | Viewed by 692 | Submission Open
Keywords: automation and robotics systems; artificial intelligence; machine learning; adaptive control; granulation
(This special issue belongs to the Section AI in Autonomous Systems)
Artificial Intelligence in Industrial Systems: From Data Acquisition to Intelligent Decision-Making submission deadline 30 Sep 2026 | 5 articles | Viewed by 15164 | Submission Open
Keywords: artificial intelligence; industrial applications; sensor systems; predictive maintenance; smart manufacturing; intelligent decision-making; data acquisition and analysis
(This special issue belongs to the Section AI in Autonomous Systems)
AI-Driven Innovations in Medical Computer Engineering and Healthcare
edited by , Ping Lu, Jens Lundström and
submission deadline 30 Sep 2026 | 2 articles | Viewed by 3506 | Submission Open
Keywords: artificial intelligence diagnostics; clinical decision support; telemedicine; remote monitoring; wearables; predictive analytics; biomedical signals; personalized medicine; healthcare automation; explainability
(This special issue belongs to the Section Medical & Healthcare AI)
Harvesting the Future: Transforming Agricultural Practices Through AI Application
edited by , and
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1696 | Submission Open
Keywords: intelligent breeding; intelligent rearing; intelligent planting; precision agriculture; intelligent pest and disease diagnosis; intelligent agricultural machinery; agricultural robots; agricultural sensors; intelligent management of agricultural production; digital village
Artificial Intelligence Potential to Solve Multiple Complex Geodetic Problems
edited by , and Desislava Ivanova
submission deadline 30 Sep 2026 | Viewed by 747 | Submission Open
Keywords: geodesy; AI; multi-source data; GNSS; geospatial data; time series analysis; geoid modeling; geohazards; climate change
Decision Intelligence and Its Applications submission deadline 30 Sep 2026 | Viewed by 476 | Submission Open
Keywords: decision intelligence; AI applications; decision understanding; explainability; XAI
Applications of Physics-Informed Machine Learning in Engineering
edited by and Jianfang Lu
submission deadline 30 Sep 2026 | Viewed by 425 | Submission Open
Keywords: PIML; flow simulation; material prediction; biomechanics and biological systems; multi-physics coupling problems; sparse or low-data engineering problems; digital twin of complex systems
AI-Powered Remote Sensing for Agriculture
edited by , Xiaofeng Ma and
submission deadline 30 Sep 2026 | Viewed by 327 | Submission Open
Keywords: artificial intelligence; remote sensing; agriculture; crop monitoring; irrigation management; yield prediction; digital mapping in agriculture; machine learning; deep learning; precision agriculture
(This special issue belongs to the Section AI Systems: Theory and Applications)
Federated and Distributed Intelligence for Sustainable Edge-Cloud Ecosystems
edited by , Amir Javed and
submission deadline 30 Sep 2026 | Viewed by 206 | Submission Open
Keywords: federated learning; distributed intelligence; sustainable edge– cloud computing; green federated learning; green IoT and IoV; privacy-preserving machine learning; smart cities and mobility; carbon-aware computing; edge intelligence; resource-constrained AI
(This special issue belongs to the Section AI Systems: Theory and Applications)
Artificial Intelligence Hardware and Software Co-Design and Neuromorphic Computing
edited by and Fangyang Shen
submission deadline 9 Oct 2026 | 1 articles | Viewed by 3034 | Submission Open
Keywords: AI hardware-software co-design; neuromorphic computing; spiking neural networks; AI accelerators; edge intelligence; brain-inspired computing; machine learning architecture; hardware-aware AI models
(This special issue belongs to the Section AI Systems: Theory and Applications)
Understanding Transformers and Large Language Models (LLMs) with Natural Language Processing (NLP) submission deadline 15 Oct 2026 | 5 articles | Viewed by 13491 | Submission Open
Keywords: bias in LLMs; human– AI language comparison; cognitive benchmarks; LLMs’ trustworthiness
Adversarial Learning and Its Applications in Healthcare submission deadline 27 Oct 2026 | 1 articles | Viewed by 4091 | Submission Open
Keywords: adversarial learning; adversarial attacks; adversarial robustness; generative adversarial learning; adversarial defenses
(This special issue belongs to the Section Medical & Healthcare AI)
AI-Driven Multimodal Biometrics for Enhanced Personal Authentication
edited by and Roberto Casula
submission deadline 30 Oct 2026 | Viewed by 573 | Submission Open
Keywords: multimodal biometrics; soft biometrics; presentation attack detection; liveness detection; adversarial machine learning; privacy-preserving learning; fairness and bias mitigation; edge/on-device AI; datasets and benchmarks; legal and ethical compliance
Recent Advances in Deep Learning and Emerging Applications
edited by , Junzo Watada and
submission deadline 31 Oct 2026 | 2 articles | Viewed by 1371 | Submission Open
Keywords: deep learning; sustainable decision-making; multimodal learning; interpretable
(This special issue belongs to the Section AI Systems: Theory and Applications)
Signal Processing Meets Large Models: Foundations and Applications for Infrared, Electro-Optical and Acoustic Imaging
edited by , , Shiwei Ma and
submission deadline 31 Oct 2026 | Viewed by 172 | Submission Open
Keywords: large models; foundation models; signal processing; infrared imaging; electro-optical imaging; acoustic imaging; multimodal fusion
(This special issue belongs to the Section AI Systems: Theory and Applications)
Applications of Artificial Intelligence in Medicine
edited by Shirly Bar-Lev and Sivan Albagli-Kim
submission deadline 1 Nov 2026 | 1 articles | Viewed by 1229 | Submission Open
Keywords: artificial intelligence; health informatics; medicine; medical imaging
(This special issue belongs to the Section Medical & Healthcare AI)
Advances and Applications in Graph Neural Networks (GNNs) submission deadline 10 Nov 2026 | 1 articles | Viewed by 2712 | Submission Open
Keywords: graph neural networks; transfer learning in GNNs; GNN applications
(This special issue belongs to the Section AI Systems: Theory and Applications)
Digital Health: AI-Driven Personalized Healthcare and Applications submission deadline 16 Nov 2026 | 2 articles | Viewed by 2999 | Submission Open
Keywords: artificial intelligence; personalized healthcare; digital health; predictive modelling; precision medicine; wearable devices; explainable AI; health informatics; clinical decision support system; federated learning
(This special issue belongs to the Section Medical & Healthcare AI)
Trustworthy AI for Autonomous Cyber Defense: Robustness, Reasoning and Real-Time Assurance
edited by and Xing Liu
submission deadline 20 Nov 2026 | 1 articles | Viewed by 1351 | Submission Open
Keywords: autonomous cyber defense; adversarial machine learning; intrusion detection; explainable and certifiable AI; moving target defense; federated/privacy-preserving learning; digital twins; edge/embedded AI; CPS/IoT security; human-in-the-loop assurance
(This special issue belongs to the Section AI in Autonomous Systems)
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