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Introduction: Inherited retinal dystrophies (IRDs) are genetically determined conditions leading to progressive vision loss. Developments in gene therapy are creating new treatment options for IRD, but require precise imaging diagnosis and monitoring...

Background/Objectives: The aberrant subclavian artery (ASA) represents the most common congenital anomaly of the aortic arch, and is frequently associated with a Kommerell diverticulum, an aneurysmal dilation at the anomalous vessel origin. This cond...

Background/Objectives: Computational studies using drift diffusion models on go/no-go escape tasks consistently show that individuals with suicidal ideation (SI) preferentially engage in active escape from negative emotional states. This study extend...

Despite advances in staged protocols and fixation techniques, treatment of pilon fractures remains a significant challenge in orthopedic trauma, with up to 21% of patients requiring revision surgery. Management of a pilon fracture that has failed ini...

Drug-resistant epilepsy affects nearly one-third of individuals with epilepsy and remains a major cause of neurological morbidity worldwide. Surgical intervention offers a potential cure, but its success critically depends on the precise identificati...

Background/Objectives: Patients with chronic kidney disease (CKD) frequently experience upper gastrointestinal (GI) symptoms such as epigastric discomfort, nausea, vomiting, and early satiety. These symptoms can contribute to malabsorption and interm...

Objectives: Prior research has found that social anxiety and intolerance of uncertainty (IU) are both related to problematic smartphone use (PSU) severity. However, research about the mediating effect of IU from social anxiety to PSU is limited. Meth...

Multiple sclerosis (MS) is a chronic, immune-mediated disorder of the central nervous system, increasingly recognized as a disease continuum that begins years before the first neurological event. Genetic susceptibility, environmental exposures, and s...

Primary biliary cholangitis (PBC) is a heterogeneous autoimmune liver disease in which clinical presentation, disease progression, and response to therapy vary markedly from patient to patient. This heterogeneity reflects its complex, multifactorial,...

The introduction of immune checkpoint inhibitors (ICIs) as a part of immunotherapy represented a therapeutic breakthrough in the landscape of cancer treatment. The action of these inhibitors consists of blocking certain inhibitory receptors in the im...