Editor’s Choice Articles are selected based on suggestions from the academic editors of Journal of Cardiovascular Development and Disease (JCDD, ISSN: 2308-3425). The Editors select a small number of recently published articles that they consider to be particularly interesting to our readers or important in their respective fields of research. You are welcome to read the 2025 Q4 Editor’s Choice Articles from JCDD.

The full list of Editor’s Choice Articles can be viewed at the following link: https://www.mdpi.com/journal/jcdd/editors_choice.

A list of these papers is provided below:

1. “Early Cytoskeletal Remodeling Drives Hypertrophic Cardiomyopathy Pathogenesis in MYH6/7 Mutant hiPSC-Derived Cardiomyocytes”
by Mohammad Shameem, Hassan Salih, Ahmed Sharara, Roshan Nicholas Rochus John, Leo Ogle and Bhairab N. Singh
J. Cardiovasc. Dev. Dis. 2025, 12(12), 500; https://doi.org/10.3390/jcdd12120500
Full text available online: https://www.mdpi.com/2308-3425/12/12/500

2. “Development and Validation of an Acute Large Animal Model for Type A Aortic Dissection”
by Ezin Deniz, Sibylle Marsen, Florian Helms, Heike Krüger, Naoki Arima, Jasmin Hanke, Ali Saad Merzah, Sadeq Al-Hasan-Al-Saegh, Sara Knigge, Saman Alhowaizy et al.
J. Cardiovasc. Dev. Dis. 2025, 12(12), 496; https://doi.org/10.3390/jcdd12120496
Full text available online: https://www.mdpi.com/2308-3425/12/12/496

3. “Cardiomyocyte Nuclear Pleomorphism in a Mouse Model of Inherited Hypertrophic Cardiomyopathy”
by Jamie R. Johnston, Isabella Leite Coscarella, Carson L. Rose, Yun Shi, Hosna Rastegarpouyani, Karissa M. Dieseldorff Jones, Jennifer M. Le Patourel, Feyikemi Ogunfuwa, Adriano S. Martins, Kathryn M. Crotty et al.
J. Cardiovasc. Dev. Dis. 2025, 12(11), 449; https://doi.org/10.3390/jcdd12110449
Full text available online: https://www.mdpi.com/2308-3425/12/11/449

4. “Human-Induced Pluripotent Stem Cell Models for Amyloid Cardiomyopathy: From Mechanistic Insights to Therapeutic Discovery”
by Yufeng Liu and Muhammad Riaz
J. Cardiovasc. Dev. Dis. 2025, 12(11), 434; https://doi.org/10.3390/jcdd12110434
Full text available online: https://www.mdpi.com/2308-3425/12/11/434

5. “Time to Reperfusion Dictates Cardiac Function and Myocardial Strain in a 7-Tesla Magnetic Resonance Imaging Rat Model”
by Mako Ito, Junpei Ueda, Sei Yasuda, Isamu Yabata, Koji Itagaki, Natsuo Banura and Shigeyoshi Saito
J. Cardiovasc. Dev. Dis. 2026, 13(1), 10; https://doi.org/10.3390/jcdd13010010
Full text available online: https://www.mdpi.com/2308-3425/13/1/10

6. “The Conducting Tissues of the Mouse Heart”
by Yolanda Macías, Damián Sánchez-Quintana, Eduardo Back Sternick and Robert H. Anderson
J. Cardiovasc. Dev. Dis. 2025, 12(11), 452; https://doi.org/10.3390/jcdd12110452
Full text available online: https://www.mdpi.com/2308-3425/12/11/452

7. “Clinical, Imaging, and Serum Biomarker Predictors of Malignant Cerebral Infarction”
by Alejandro Rodríguez-Vázquez, Salvatore Rudilosso, Antonio Doncel-Moriano, Andrea Cabero-Arnold, Carlos Laredo, Darío Ramis, David Moraleja, Mònica Serrano, Yolanda González-Romero, Arturo Renú et al.
J. Cardiovasc. Dev. Dis. 2025, 12(10), 392; https://doi.org/10.3390/jcdd12100392
Full text available online: https://www.mdpi.com/2308-3425/12/10/392

8. “Iron Deficiency in Heart Failure: Cellular Mechanisms and Therapeutic Implications”
by Anastasios Tsarouchas, Vassilios P. Vassilikos, Dimitrios Mouselimis, Christodoulos E. Papadopoulos, Dimitrios Tachmatzidis, Aikaterini Vassilikou and Constantinos Bakogiannis
J. Cardiovasc. Dev. Dis. 2025, 12(11), 415; https://doi.org/10.3390/jcdd12110415
Full text available online: https://www.mdpi.com/2308-3425/12/11/415

9. “The Association Between Short-Term Blood Pressure Variability and Inflammation in Healthy Young Adults”
by Charles J. Weeks, Bayu B. Bekele, Michelle Altvater, Jie Cheng, Haidong Zhu, Ying Huang, Deborah A. Jehu, Abigayle B. Simon, Wenjun Li and Yanbin Dong
J. Cardiovasc. Dev. Dis. 2025, 12(10), 399; https://doi.org/10.3390/jcdd12100399
Full text available online: https://www.mdpi.com/2308-3425/12/10/399

10. “2020 ESC Guidelines on Sports Cardiology: Impact of CMR Criteria on Return-to-Play Clearance After Acute Myocarditis”
by Carlo Maria Gallinoro, Alessandra Scatteia, Dario Catapano, Carmine Emanuele Pascale, Giuseppe Russo, Franca Di Meglio and Santo Dellegrottaglie
J. Cardiovasc. Dev. Dis. 2025, 12(12), 469; https://doi.org/10.3390/jcdd12120469
Full text available online: https://www.mdpi.com/2308-3425/12/12/469