
Biomolecules | Highly Viewed Papers and Hot Topic Special Issues in the “Molecular Biophysics: Structure, Dynamics, and Function” Section
We are delighted to share a collection of highly viewed papers and some successful Special Issues in the Section “Molecular Biophysics: Structure, Dynamics, and Function” that were published in Biomolecules (ISSN: 2218-273X) in 2024 and 2025. What follows is a list of articles and Special Issues that we believe may be of interest to you.
Relevant papers:
“Ubiquitin-Specific Protease Inhibitors for Cancer Therapy: Recent Advances and Future Prospects”
by Mohamad Bakkar, Sara Khalil, Komal Bhayekar, Narva Deshwar Kushwaha, Amirreza Samarbakhsh, Sadaf Dorandish, Holly Edwards, Q. Ping Dou, Yubin Ge and Navnath S. Gavande
Biomolecules 2025, 15(2), 240; https://doi.org/10.3390/biom15020240
Available online: https://www.mdpi.com/2218-273X/15/2/240
“Updated Review on Natural Polyphenols: Molecular Mechanisms, Biological Effects, and Clinical Applications for Cancer Management”
by Zainab Sabry Othman Ahmed, Elyas Khan, Nathan Elias, Alhussein Elshebiny and Qingping Dou
Biomolecules 2025, 15(5), 629; https://doi.org/10.3390/biom15050629
Available online: https://www.mdpi.com/2218-273X/15/5/629
“Piezo1 Channel Activators Yoda1 and Yoda2 in the Context of Red Blood Cells”
by Min Qiao, Reetta Penttinen, Ariel Coli, Nicoletta Murciano, Felix M. Maurer, Christian Wagner, Maria Giustina Rotordam and Lars Kaestner
Biomolecules 2025, 15(8), 1110; https://doi.org/10.3390/biom15081110
Available online: https://www.mdpi.com/2218-273X/15/8/1110
“Artificial Intelligence: A New Tool for Structure-Based G Protein-Coupled Receptor Drug Discovery”
by Jason Chung, Hyunggu Hahn, Emmanuel Flores-Espinoza and Alex R. B. Thomsen
Biomolecules 2025, 15(3), 423; https://doi.org/10.3390/biom15030423
Available online: https://www.mdpi.com/2218-273X/15/3/423
“Multiple Mechanisms to Regulate Actin Functions: “Fundamental” Versus Lineage-Specific Mechanisms and Hierarchical Relationships”
by Taro Q. P. Uyeda, Yosuke Yamazaki, Saku T. Kijima, Taro Q. P. Noguchi and Kien Xuan Ngo
Biomolecules 2025, 15(2), 279; https://doi.org/10.3390/biom15020279
Available online: https://www.mdpi.com/2218-273X/15/2/279
“MTPrompt-PTM: A Multi-Task Method for Post-Translational Modification Prediction Using Prompt Tuning on a Structure-Aware Protein Language Model”
by Ye Han, Fei He, Qing Shao, Duolin Wang and Dong Xu
Biomolecules 2025, 15(6), 843; https://doi.org/10.3390/biom15060843
Available online: https://www.mdpi.com/2218-273X/15/6/843
“Non-Canonical, Strongly Selective Protein Disulfide Isomerases as Anticancer Therapeutic Targets”
by Mary E. Law, Zaafir M. Dulloo, Brian Hardy, Ania Kelegama, Reagan Clark, Mariana Rivas Montbrun, Gabriella Antmann, Srihith Nooka, Ronald K. Castellano and Brian K. Law
Biomolecules 2025, 15(8), 1146; https://doi.org/10.3390/biom15081146
Available online: https://www.mdpi.com/2218-273X/15/8/1146
“Chemotaxis and Related Signaling Systems in Vibrio cholerae”
by Fuga Omori, Hirotaka Tajima, Sotaro Asaoka, So-ichiro Nishiyama, Yoshiyuki Sowa and Ikuro Kawagishi
Biomolecules 2025, 15(3), 434; https://doi.org/10.3390/biom15030434
Available online: https://www.mdpi.com/2218-273X/15/3/434
“Defibrotide for Protecting Against and Managing Endothelial Injury in Hematologic Malignancies and COVID-19”
by Edward Richardson, Clifton C. Mo, Eleonora Calabretta, Francesco Corrado, Mehmet H. Kocoglu, Rebecca M. Baron, Jean Marie Connors, Massimo Iacobelli, Lee-Jen Wei, Emily J. Benjamin et al.
Biomolecules 2025, 15(7), 1004; https://doi.org/10.3390/biom15071004
Available online: https://www.mdpi.com/2218-273X/15/7/1004
“Aptamer Development for SARS-CoV-2 and Omicron Variants Using the Spike Protein Receptor Binding Domain as a Potential Diagnostic Tool and Therapeutic Agent”
by Prasanna V. Shekar, Anuj Kumar, Nirmitee Mulgaonkar, Samneet Kashyap, Gourav Choudhir, Sandun Fernando and Sachin Rustgi
Biomolecules 2025, 15(6), 805; https://doi.org/10.3390/biom15060805
Available online: https://www.mdpi.com/2218-273X/15/6/805
Special Issues:
“Recent Advances in Supramolecular Motility Machinery of Microorganisms”
Guest Editors: Dr. Tohru Minamino, Dr. Yusuke V. Morimoto and Dr. Daisuke Nakane
Published papers: 11
Viewed by 23,860+
“Bioactive Molecules: Structures, Functions and Potential Uses for Cancer Prevention and Targeted Therapies (2nd Edition)”
Guest Editor: Prof. Dr. Qingping Dou
Published papers: 10
Viewed by 41,560+
“Advances in Cellular Biophysics: Transport and Mechanics”
Guest Editors: Prof. Dr. Boris Musset and Prof. Dr. Peter Pohl
Published papers: 7
Viewed by 14,665+
“Genetic and Structural Analyses of Coronaviruses: Insights into SARS-CoV-2 and Beyond”
Guest Editor: Prof. Dr. Stefano Pascarella
Published papers: 8
Viewed by 15,495+
“Harnessing Protein Design and Engineering for Therapeutic Applications”
Guest Editors: Dr. Julia Shifman and Dr. Norman Metanis
Published papers: 5
Viewed by 19,255+
“Innovative Biomolecular Structure Analysis Techniques”
Guest Editor: Dr. Tzanko I. Doukov
Published papers: 6
Viewed by 10,165+
“Protein Biophysics”
Guest Editors: Prof. Dr. Vladimir N. Uversky and Dr. Orkid Coskuner-Weber
Published papers: 4
Viewed by 4165+