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Applied Biosciences, Volume 4, Issue 1

March 2025 - 16 articles

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Articles (16)

  • Review
  • Open Access
1 Citations
2,736 Views
21 Pages

Animal experiments have long been used as an educational tool in pharmacological education; however, from the perspective of animal welfare, it is necessary to decrease the number of animals used. ingAlthough using of simulators is effective, the dev...

  • Article
  • Open Access
1,989 Views
15 Pages

Antibiofilm Activity of Protamine Against the Vaginal Candidiasis Isolates of Candida albicans, Candida tropicalis and Candida krusei

  • Sivakumar Jeyarajan,
  • Indira Kandasamy,
  • Raja Veerapandian,
  • Jayasudha Jayachandran,
  • Shona Chandrashekar,
  • Kalimuthusamy Natarajaseenivasan,
  • Prahalathan Chidambaram and
  • Anbarasu Kumarasamy

Candida species, normally part of the healthy human flora, can cause severe opportunistic infections when their population increases. This risk is even greater in immunocompromised individuals. Women using intrauterine contraceptive devices (IUDs) ar...

  • Article
  • Open Access
4 Citations
2,755 Views
11 Pages

Exploring the Anxiolytic, Antidepressant, and Immunomodulatory Effects of Cannabidiol in Acute Stress Rat Models

  • Hristina Zlatanova-Tenisheva,
  • Maria Georgieva-Kotetarova,
  • Natalia Vilmosh,
  • Ilin Kandilarov,
  • Delyan Delev,
  • Tihomir Dermendzhiev and
  • Ilia Dimitrov Kostadinov

Cannabidiol (CBD), a non-psychoactive compound derived from Cannabis sativa, is believed to have anxiety-reducing and antidepressant effects. However, existing data are inconsistent, likely due to variations in experimental designs, dosages, and stre...

  • Review
  • Open Access
4,490 Views
13 Pages

Cancer pain is a highly prevalent problem and one of the most distressing symptoms in cancer patients. The management of cancer pain is one of the most significant challenges in the care of these patients. Cancer pain must be treated quickly and effe...

  • Article
  • Open Access
1 Citations
3,028 Views
18 Pages

Multi-Criteria Decision Analysis in Drug Discovery

  • Rafał A. Bachorz,
  • Michael S. Lawless,
  • David W. Miller and
  • Jeremy O. Jones

Drug discovery is inherently a multi-criteria optimization problem. In the first instance, it involves a tremendously large chemical space, where each compound can be characterized by multiple molecular and biological properties. Modern computational...

  • Review
  • Open Access
1 Citations
7,403 Views
21 Pages

Immune thrombocytopenia, formerly idiopathic thrombocytopenia purpura (ITP), is an autoimmune disease characterized by the depletion of platelets below 100,000/µL when other causes of thrombocytopenia have been ruled out. It is associated with...

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Appl. Biosci. - ISSN 2813-0464