- Communication
Drug Repositioning in Intensive Care Patients and Pharmacokinetic Variability: The Illustration of Hydroxychloroquine
- Gwendoline Ragonnet,
- Elisabeth Jouve,
- Lionel Velly,
- Marc Leone,
- Gary Duclos,
- Jeremy Bourenne,
- Karim Harti Souab,
- Caroline Solas and
- Romain Guilhaumou
During the SARS-CoV-2 pandemic, hydroxychloroquine (HCQ), was among the first drugs to be tested due to demonstrated in vitro antiviral activity against SARS-CoV-2. Pharmacokinetic variability was expected due to the frequent comorbidities and pathop...

