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Onco, Volume 1, Issue 1

September 2021 - 5 articles

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Articles (5)

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Article

1 Citations

4,868 Views

11 Pages

Clinical Application of Next-Generation Sequencing in Recurrent Glioblastoma

Daniel Zeitouni,
Michael P. Catalino,
Jordan Wise,
Sean McCabe,
Kathryn Pietrosimone,
Naim Rashid and
Simon Khagi

Onco2021, 1(1), 38-48;https://doi.org/10.3390/onco1010005

17 August 2021

BACKGROUND: Glioblastoma (GBM) is driven by various genomic alterations. Next-generation sequencing (NGS) could yield targetable alterations that might impact outcomes. The goal of this study was to describe how NGS can inform targeted therapy (TT) i...

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Review

2 Citations

4,943 Views

13 Pages

Targeting HMGB1 in the Treatment of Non-Small Cell Lung Adenocarcinoma

Brady Anderson,
Mary Vue,
Nya Gayluak,
Sarah Jane Brown,
Lynne T. Bemis and
Glenn E. Simmons

Onco2021, 1(1), 25-37;https://doi.org/10.3390/onco1010004

4 June 2021

Evidence of immunogenic cell death as a predictor of response to cancer therapy has increased interest in the high molecular group box 1 protein (HMGB1). HMGB1 is a nuclear protein associated with chromatin organization and DNA damage repair. HMGB1 i...

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Editorial

2,886 Views

2 Pages

Do We Really Need Another Oncology Journal?

Fred Saad

Onco2021, 1(1), 23-24;https://doi.org/10.3390/onco1010003

8 April 2021

As the inaugural editor in chief of the journal Onco I am very proud to take on the challenge of bringing to life a new journal dedicated to promoting the new developments and management of this challenging disease [...]

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Systematic Review

5 Citations

5,337 Views

20 Pages

The Impact of Immune Checkpoint-Inhibitors Therapy in Urinary Bladder Cancer

Ana Lúcia Silva,
Pedro Abreu-Mendes,
Diana Martins and
Fernando Mendes

Onco2021, 1(1), 3-22;https://doi.org/10.3390/onco1010002

4 March 2021

Bladder cancer (BC) is one of the most common cancers in the world. From an early age, it was observed that chronic inflammation is associated with conditions favorable to the development of tumors, as well as the tumor microenvironment. Moreover, re...

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