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Chemistry, Volume 6, Issue 2

April 2024 - 7 articles

Cover Story: Global antimicrobial resistance has encouraged efforts to evaluate new drug candidates, such as ocellatins, a group of antimicrobial peptides found in the skin secretions of anurans of the Leptodactylidae family. This paper reports the isolation of a new ocellatin from the species Leptodactylus vastus. The peptide was called ocellatin-VT and especially inhibited Gram-negative bacteria growth, with the most activity against Acinetobacter baumannii and Escherichia coli. Ocellatin-VT was weakly cytotoxic to B16-F10 cancer cells and showed low-level hemolytic activity. Thus, a new ocellatin was isolated from L. vastus skin secretions that was active against non-resistant and multidrug-resistant bacteria. View this paper

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Article

1 Citations

2,095 Views

12 Pages

First Report of Ocellatin-VT from the Skin Secretion of Leptodactylus vastus Lutz (Amphibia: Leptodactylidae)

Tulíbia Laurindo Silva,
Géssica Gomes Barbosa,
Carlos José Correia de Santana,
Patrícia Maria Guedes Paiva,
Mariana S. Castro and
Thiago Henrique Napoleão

Chemistry2024, 6(2), 333-344;https://doi.org/10.3390/chemistry6020019

8 April 2024

The global emergency of antimicrobial resistance has drawn several efforts to evaluate new drug candidates, such as natural defensive biomolecules. Ocellatins are a group of antimicrobial peptides found in anurans of the Leptodactylidae family. This...

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Article

3 Citations

2,263 Views

10 Pages

NEXAFS and XPS Studies of Co Doped Bismuth Magnesium Tantalate Pyrochlores

Nadezhda A. Zhuk,
Boris A. Makeev,
Aleksandra V. Koroleva,
Sergey V. Nekipelov and
Olga V. Petrova

Chemistry2024, 6(2), 323-332;https://doi.org/10.3390/chemistry6020018

3 April 2024

Co doped bismuth magnesium tantalate with a pyrochlore structure (sp. gr. Fd-3m) was synthesized for the first time using the standard ceramic method. Single phase Bi2Mg1−xCoxTa2O9 samples were found to be formed when x < 0.7 in the X-ray ph...

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Communication

5 Citations

4,174 Views

11 Pages

In-Site Growth of Efficient NiFeOOH/NiFe-LDH Electrodes: A Streamlined One-Step Methodology

Jing Ning,
Li Xu,
Wei Xu,
Guizhen Li and
Wen Zhang

Chemistry2024, 6(2), 312-322;https://doi.org/10.3390/chemistry6020017

31 March 2024

Oxygen evolution reactions (OER) are often the decisive step in determining the water electrolysis rate. The first row of transition metals and their derivatives, represented by Ni and Fe, have attracted much attention due to their excellent OER perf...

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Article

2 Citations

2,325 Views

13 Pages

Hydrophobin-Coated Perfluorocarbon Microbubbles with Strong Non-Linear Acoustic Response

Valentina Dichiarante,
Giuseppina Salzano,
Philippe Bussat,
Emmanuel Gaud,
Samir Cherkaoui and
Pierangelo Metrangolo

Chemistry2024, 6(2), 299-311;https://doi.org/10.3390/chemistry6020016

26 March 2024

Gas-filled microbubbles are well-established contrast agents for ultrasound imaging and widely studied as delivery systems for theranostics. Herein, we have demonstrated the promising potential of the hydrophobin HFBII—a fungal amphiphilic prot...

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Article

7 Citations

6,891 Views

16 Pages

Breathable Iron-Based MIL-88 Framework as Dye Adsorbent in Aqueous Solution

Dita A. Nurani,
Nabila Anisa,
Irena Khatrin,
Yasmine,
Grandprix T. M. Kadja and
Yuni K. Krisnandi

Chemistry2024, 6(2), 283-298;https://doi.org/10.3390/chemistry6020015

14 March 2024

Metal–organic frameworks (MOFs) have been observed to exclusively eliminate dyes confined within their respective pores. In this investigation, the synthesis of a breathable MOF structure, MIL-88B(Fe), was pursued with the objective of circumve...

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Article

4 Citations

2,871 Views

11 Pages

Development and Validation of a Chromatographic Method for Ibrutinib Determination in Human and Porcine Skin

Lucas F. F. Albuquerque,
Maria Victoria Souto,
Felipe Saldanha-Araujo,
Juliana Lott Carvalho,
Tais Gratieri,
Marcilio Cunha-Filho and
Guilherme M. Gelfuso

Chemistry2024, 6(2), 272-282;https://doi.org/10.3390/chemistry6020014

27 February 2024

Ibrutinib (IBR) is a tyrosine kinase inhibitor investigated for treating solid and non-solid tumors. Considering the advantages that a topical application of IBR could generate in terms of dose reduction and side effects in skin cancer treatment, thi...

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Article

6 Citations

2,522 Views

8 Pages

Chemical Composition of the Essential Oils from Goniothalamus tortilipetalus M.R.Hend. and Their Antioxidant and Antibacterial Activities

Aknarin Anatachodwanit,
Phunrawie Promnart,
Suwanna Deachathai,
Tharakorn Maneerat,
Rawiwan Charoensup,
Thidarat Duangyod and
Surat Laphookhieo

Chemistry2024, 6(2), 264-271;https://doi.org/10.3390/chemistry6020013

23 February 2024

This work was the first investigation of the essential oil composition of Goniothalamus tortilipetalus M.R.Hend. The aim of this study is to investigate the essential oil composition extracted from different parts of Goniothalamus tortilipetalus M.R....

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