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  • Clinical and Translational Neuroscience is published by MDPI from Volume 5 Issue 2 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with SAGE.

Clinical and Translational Neuroscience, Volume 2, Issue 1

2018 January - 18 articles

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Articles (18)

  • Article
  • Open Access
694 Views
5 Pages

For most sighted people, looking into a mirror helps to consolidate a visual and spatial concept of the self. This concept connects both theoretically and substantively to other elements of identity. Similarly, observing the bodies of others plays a...

  • Editorial
  • Open Access
698 Views
3 Pages

It’s Been a Decade: The Swiss Young Neurosurgeons Society

  • M Murek,
  • A Jilch,
  • A El-Rahal,
  • I Zubak,
  • C Fung,
  • J Abu-Isa,
  • J Fichtner,
  • B Actor,
  • N Khan and
  • P Schucht
  • + 3 authors

The Swiss Young Neurosurgeons Society (SYNS) comes to life in 2008, creating a community renowned for its unique spirit, a platform dedicated to lifelong teaching and learning. In 2008, a small group of Swiss residents found a cross-canton training p...

  • Article
  • Open Access
2 Citations
758 Views
10 Pages

We wish to highlight the political impact of neuroscientific societies as forums of cross-border communication from a historical point of view. We trace the efforts of Constantin von Monakow, a founder of Swiss Neurology, and Cornelis Winkler, one of...

  • Project Report
  • Open Access
6 Citations
933 Views
8 Pages

Memory Center: The Lausanne Model

  • Daniel Damian,
  • Olivier Rouaud,
  • Bogdan Draganski,
  • Andrea Brioschi-Guevara,
  • Murielle Bortolotti,
  • Marie-Helene Laouadi and
  • Jean-François Demonet

We present the multidisciplinary approach toward the diagnostic and treatment of patients with cognitive complaints adopted within the Leenaards Memory Centre at the University Hospital of Lausanne in Switzerland. Our strategy combines clinical evalu...

  • Article
  • Open Access
18 Citations
947 Views
7 Pages

Blood biomarkers are increasingly beginning to play a role in the diagnosis, management, and prognostication of patients with acute ischemic stroke. While imaging biomarkers have played the largest role in determining acute therapies, blood-based bio...

  • Article
  • Open Access
3 Citations
931 Views
5 Pages

Since almost 50 years L-Dopa is the gold standard for the treatment of patients with Parkinson’s disease (PD). For the first time, a specific chemical abnormality was found in a specific brain disorder. It has been shown that the striatal dopamine (D...

  • Article
  • Open Access
941 Views
6 Pages

Background: Anti-CD20 therapies are an emerging treatment strategy in multiple sclerosis (MS). Objective: Retrospective analysis of efficacy and safety in an MS cohort treated with rituximab (RTX) with identification of potential treatment response p...

  • Technical Note
  • Open Access
699 Views
3 Pages

Recurrent Syncope Due to Carotid Sinus Hypersensitivity in Cerebral Atherosclerosis

  • Björn Zörner,
  • Jan Steffel,
  • Michael Linnebank and
  • Alexander A Tarnutzer

A 62-year-old female with a history of stroke due to cerebral arteriosclerosis suffered from recurrent fainting (<10 s) provoked by rapid head movements up to four times per month for at least two years. There was no evidence of new strokes in rep...

  • Article
  • Open Access
9 Citations
1,035 Views
9 Pages

Inflammaging in the Intervertebral Disc

  • Aleksandra Sadowska,
  • Oliver Nic Hausmann and
  • Karin Wuertz-Kozak

Degeneration of the intervertebral disc – triggered by ageing, mechanical stress, traumatic injury, infection, inflammation and other factors – has a significant role in the development of low back pain. Back pain not only has a high prevalence, but...

  • Technical Note
  • Open Access
686 Views
5 Pages

Still Restricted Usability of Imaging Criteria in Therapeutic Decisions for Acute Ischemic Stroke Treatment

  • Simon Jung,
  • Thomas Horvath,
  • Sarah Zimmel,
  • Pascal J Mosimann,
  • Hakim Arsany,
  • Marcel Arnold and
  • Claudio Bassetti

A 90-year-old woman developed a severe stroke (National Institutes of Health Stroke Scale Score (NIHSS) 24) due to an occlusion of the left carotid T. Computed tomography 60 min after symptom onset showed a large area of tissue at risk with a relativ...

  • Article
  • Open Access
7 Citations
828 Views
5 Pages

Hydropic Ear Disease—Translation of Imaging into Clinical Practice: Clinical Image Case

  • Robert Gürkov,
  • Roger Kalla,
  • Rebecca Maxwell and
  • Maximilian Patzig

A 45-year-old man presented to the neurotology clinic, suffering from recurrent attacks of vertigo associated with falls, of unknown origin. Pure tone audiometry revealed a profound right-sided and mild left-sided pantonal sensorineural hearing loss....

  • Review
  • Open Access
9 Citations
858 Views
7 Pages

Aquaporins in Neurological Disorders

  • Lorenz Hirt,
  • Melanie Price,
  • Corinne Benakis and
  • Jérôme Badaut

Aquaporins (AQPs) are water channel molecules that allow the passage of water through the lipid bilayers of cell membranes. AQP1, AQP4 and AQP9 are expressed in the central nervous system and AQP4 is well known as the target of auto-antibodies in Dev...

  • Article
  • Open Access
1 Citations
879 Views
7 Pages

New Patterns of Magnetic Resonance Images in High-Grade Glioma Patients Treated with Bevacizumab (Avastin®)

  • J Gariani,
  • Af Hottinger,
  • A Ben Aissa,
  • Ma Korchi,
  • Jose Boto,
  • K Gariani,
  • Ko Lovblad and
  • Mi Vargas

Objectives: To identify new magnetic resonance imaging (MRI) patterns in patients with high-grade glioma treated with bevacizumab (Avastin®). Methods: The retrospective study was approved by the institutional review board. An extended case series of...

  • Article
  • Open Access
793 Views
10 Pages

While the physiology, histology and stem cell biology of smell are active fields of contemporary research, smell is probably the sense that physicians knew the least about prior to the 20th century. Joseph-Hippolyte Cloquet (1787–1840) was an anatomi...

  • Project Report
  • Open Access
2 Citations
818 Views
3 Pages

Certification of Stroke Centre and Stroke Units in Switzerland

  • Marcel Arnold,
  • Stefan Engelter,
  • Philippe Lyrer,
  • Susanne Renaud,
  • Patrik Michel and
  • Krassen Nedeltchev

In Switzerland, since 2011, a mandatory certification system for stroke units (SUs) and stroke centres has been successfully implemented. Detailed criteria for stroke centres and SUs focusing on leadership, specialized staff, infrastructure, diagnost...

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Clin. Transl. Neurosci. - ISSN 2514-183X