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Tropical Medicine and Infectious Disease, Volume 9, Issue 6

2024 June - 19 articles

Cover Story: The emergence of antimicrobial-resistant (AMR) strains of pathogenic Escherichia coli in camel populations raises significant concerns regarding the zoonotic transmission of resistant bacteria. Camel herds, pivotal in various regions, serve as potential reservoirs for pathogenic E. coli with multidrug resistance. Understanding the zoonotic potential of these strains is paramount to mitigate the risk of transmission to humans and prevent the spread of antimicrobial resistance. Our study delves into the molecular markers and AMR profiles of extraintestinal pathogenic E. coli (ExPEC) strains isolated from septicaemic camel calves, some of which showed multidrug- or colistin resistance, while some of them showed the highly mucous phenotype termed hypermucoviscosity, which is rarely reported in E. coli. View this paper
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Articles (19)

  • Article
  • Open Access
7 Citations
4,619 Views
13 Pages

Epidemiological Characteristics of Overseas-Imported Infectious Diseases Identified through Airport Health-Screening Measures: A Case Study on Fuzhou, China

  • Hong Li,
  • Yan Yang,
  • Jiake Chen,
  • Qingyu Li,
  • Yifeng Chen,
  • Yilin Zhang,
  • Shaojian Cai,
  • Meirong Zhan,
  • Chuancheng Wu and
  • Jianjun Xiang
  • + 1 author

Background: This study aimed to examine the epidemiological characteristics of imported infections and assess the effectiveness of border health screening in detecting imported diseases. Methods: We obtained infection data for 2016 to 2019 from the F...

(This article belongs to the Section Infectious Diseases)
  • Review
  • Open Access
18 Citations
6,181 Views
18 Pages

Knowledge Gaps and Educational Opportunities in Congenital Toxoplasmosis: A Narrative Review of Brazilian and Global Perspectives

  • David Richer Araujo Coelho,
  • Rogerio Oliveira da Luz,
  • Catiucia Soares Melegario,
  • Willians Fernando Vieira and
  • Lilian Maria Garcia Bahia-Oliveira

Congenital toxoplasmosis is a parasitic disease caused by the transmission of the protozoan Toxoplasma gondii during pregnancy that can potentially cause severe consequences for the fetus or neonates. The disease disproportionately impacts the global...

(This article belongs to the Special Issue Recent Advances in Toxoplasma gondii Infection and Toxoplasmosis)
  • Article
  • Open Access
2 Citations
2,421 Views
12 Pages

Rapid Discriminative Identification of the Two Predominant Echinococcus Species from Canine Fecal Samples in the Tibetan Region of China by Loop-Mediated Isothermal Amplification–Lateral Flow Dipstick Assay

  • Xinyue Lv,
  • Jiajia Ai,
  • Xiaojin Mo,
  • Haojie Ding,
  • Sofia Litchev,
  • Entung Lu,
  • Youhong Weng,
  • Qing He,
  • Quzhen Gongsang and
  • Qingming Kong
  • + 5 authors

Echinococcosis poses a significant concern in the fields of public health and veterinary care as it can be transmitted between animals and humans. The primary endemic subtypes are cystic echinococcosis (CE) and alveolar echinococcosis (AE), which res...

(This article belongs to the Special Issue Echinococcosis: From Parasite–Host Interaction to Rapid Detection)
  • Article
  • Open Access
6 Citations
6,245 Views
14 Pages

Human Skin as an Ex Vivo Model for Maintaining Mycobacterium leprae and Leprosy Studies

  • Natália Aparecida de Paula,
  • Marcel Nani Leite,
  • Daniele Ferreira de Faria Bertoluci,
  • Cleverson Teixeira Soares,
  • Patrícia Sammarco Rosa and
  • Marco Andrey Cipriani Frade

The in vitro cultivation of M. leprae has not been possible since it was described as causing leprosy, and the limitation of animal models for clinical aspects makes studies on leprosy and bacteria–human host interaction a challenge. Our aim wa...

  • Article
  • Open Access
2 Citations
2,687 Views
13 Pages

Association between KSHV-Specific Humoral and T Cell Responses with Recurrence of HIV-Associated Kaposi Sarcoma

  • Marie-Claire Mukasine,
  • Gina Mulundu,
  • Musonda Kawimbe,
  • Keagan Mutale,
  • Chibamba Mumba,
  • Salum J. Lidenge and
  • Owen Ngalamika

Kaposi sarcoma (KS) is an AIDS-defining angio-proliferative malignancy, with the Kaposi sarcoma-associated herpes virus (KSHV) as its etiologic agent. Upon treatment with chemotherapy, a proportion of HIV-associated KS patients experience disease rec...

(This article belongs to the Section Infectious Diseases)
  • Article
  • Open Access
7 Citations
2,857 Views
13 Pages

Molecular Detection of Leishmania spp. and Blood Source of Female Sand Flies in the Parque Estadual do Rio Doce and Municipality of Timóteo, Minas Gerais, Brazil

  • Cristian Ferreira de Souza,
  • Carlos Alberto dos Santos,
  • Paula Dias Bevilacqua,
  • José Dilermando Andrade Filho and
  • Reginaldo Peçanha Brazil

Leishmaniasis is a group of diseases caused by protozoa of the genus Leishmania and is transmitted by the bite female sand fly. The present work is characterized as a descriptive study in two areas: a forest area located in the Parque Estadual do Rio...

(This article belongs to the Special Issue Leishmaniasis: Vector-Host-Pathogen Interactions in Health and Disease)
  • Article
  • Open Access
4 Citations
3,332 Views
12 Pages

Impact of Neurological Complications on Long-Term Outcomes in Patients with Infective Endocarditis

  • Pedro Henrique Oliveira Murta Pinto,
  • Isabela Galizzi Fae,
  • Gustavo Brandão Oliveira,
  • Roni Arley Silva Duque,
  • Mauricio Vitor Machado Oliveira,
  • Luan Salvador Machado Barbalho,
  • André Oliveira Parreiras,
  • Fernanda Alves Gelape,
  • Fernanda Sophya Leite Cambraia and
  • Maria Carmo Pereira Nunes
  • + 6 authors

Neurological complications are frequent during the active course of infective endocarditis (IE), and they are associated with high in-hospital mortality rates. However, limited data exist on the prognostic value of these complications for late outcom...

  • Article
  • Open Access
2 Citations
4,161 Views
10 Pages

Risk Factors Associated with Loss to Follow-Up during Tuberculosis Treatment in the Sanatorium Hospital of Luanda, Angola

  • Domingos Vita,
  • Maria Luisa Aznar,
  • Joan Martínez-Campreciós,
  • Debora Cristina Maindo Sebastiao Kansietoko and
  • Israel Molina

Background: Tuberculosis (TB) continues to be a serious public health threat that affects the most vulnerable populations. Patients who are lost to follow-up (LTFU) after TB diagnosis still represent one of the biggest challenges to TB control. Metho...

(This article belongs to the Section Infectious Diseases)
  • Article
  • Open Access
2 Citations
3,220 Views
13 Pages

Leprosy in Spain: A Descriptive Study of Admissions at Fontilles Sanatorium between 1909 and 2020

  • Cristina Juan,
  • Lourdes Lledó,
  • Miguel Torralba,
  • José Ramón Gómez and
  • Consuelo Giménez

Background: The study aimed to characterize patients with leprosy admitted to Fontilles throughout the 20th and 21st centuries, focusing on differences across three periods (I, II, and III). It also explored variables linked to patient survival. Meth...

(This article belongs to the Section Neglected and Emerging Tropical Diseases)
  • Article
  • Open Access
7 Citations
4,077 Views
18 Pages

Therapeutic Modulation of Arginase with nor-NOHA Alters Immune Responses in Experimental Mouse Models of Pulmonary Tuberculosis including in the Setting of Human Immunodeficiency Virus (HIV) Co-Infection

  • Sadhana Chauhan,
  • Rebecca J. Nusbaum,
  • Matthew B. Huante,
  • Alex J. Holloway,
  • Mark A. Endsley,
  • Benjamin B. Gelman,
  • Joshua G. Lisinicchia and
  • Janice J. Endsley

L-arginine metabolism is strongly linked with immunity to mycobacteria, primarily through the antimicrobial activity of nitric oxide (NO). The potential to modulate tuberculosis (TB) outcomes through interventions that target L-arginine pathways are...

(This article belongs to the Special Issue Ending Tuberculosis Epidemic: Current Status and Future Prospects)
  • Article
  • Open Access
9 Citations
3,722 Views
13 Pages

Are Pathogenic Leptospira Species Ubiquitous in Urban Recreational Parks in Sydney, Australia?

  • Xiao Lu,
  • Mark E. Westman,
  • Rachel Mizzi,
  • Christine Griebsch,
  • Jacqueline M. Norris,
  • Cheryl Jenkins and
  • Michael P. Ward

Leptospirosis is a zoonotic disease caused by the spirochete bacteria Leptospira spp. From December 2017 to December 2023, a total of 34 canine leptospirosis cases were reported in urban Sydney, Australia. During the same spatio-temporal frame, one l...

  • Article
  • Open Access
9 Citations
3,199 Views
9 Pages

Fungal Keratitis, Epidemiology and Outcomes in a Tropical Australian Setting

  • Leah N. Kim,
  • Hema Karthik,
  • Kate Elizabeth Proudmore,
  • Sarah Elizabeth Kidd and
  • Robert William Baird

Background: Fungal keratitis is an ophthalmic emergency that can cause visual impairment and blindness. We reviewed the epidemiology and clinical features of fungal keratitis in a tropical Australian setting. Objectives: To document the clinical and...

  • Article
  • Open Access
3 Citations
4,014 Views
13 Pages

Community Feedback on Mass Medicines Administration for Neglected Tropical Diseases in Federal Capital Territory, Abuja, Nigeria

  • Juliana Ajuma Amanyi-Enegela,
  • Jacqueline Azumi Badaki,
  • Gbenga Olorunshola Alege,
  • Faizah Okunade,
  • Joseph Kumbur,
  • Rinpan Ishaya,
  • Donald Ashikeni,
  • Mohammad Babar Qureshi and
  • Girija Sankar

The World Health Organization (WHO) recommends the use of annual mass drug administration (MDA) as the strategy for controlling and eliminating the five preventive chemotherapy neglected tropical diseases (PC-NTDs). The success of MDAs hinges on comm...

(This article belongs to the Special Issue Community Engagement and Neglected Tropical Diseases (NTDs))
  • Communication
  • Open Access
2 Citations
2,682 Views
9 Pages

Applicability of Traps for Collecting Mosquito Immatures (Diptera: Culicidae) for Entomological Surveillance of Arbovirus Vectors in a Remnant of the Atlantic Forest, Rio de Janeiro State, Brazil

  • Rayane Dias,
  • Cecilia Ferreira de Mello,
  • Shayenne Olsson Freitas Silva,
  • Hélcio Reinaldo Gil-Santana,
  • Ana Laura Carbajal-de-la-Fuente and
  • Jeronimo Alencar

Diverse larval habitats significantly influence female mosquito oviposition. Utilizing traps that simulate these habitats is helpful in the study of the bioecology and characteristics of pathogen-transmitting species during oviposition. This study ev...

(This article belongs to the Special Issue Recent Progress in Mosquito-Borne Diseases)
  • Article
  • Open Access
8 Citations
2,978 Views
14 Pages

Angiostrongylus cantonensis, a zoonotic parasite, can invade the human central nervous system (CNS) and cause acute eosinophilic meningitis or eosinophilic meningoencephalitis. Mice infected with A. cantonensis show elevated levels of pro-inflammator...

  • Article
  • Open Access
2 Citations
3,489 Views
13 Pages

Molecular Markers and Antimicrobial Resistance Patterns of Extraintestinal Pathogenic Escherichia coli from Camel Calves Including Colistin-Resistant and Hypermucoviscuous Strains

  • Domonkos Sváb,
  • Zoltán Somogyi,
  • István Tóth,
  • Joseph Marina,
  • Shantymol V. Jose,
  • John Jeeba,
  • Anas Safna,
  • Judit Juhász,
  • Péter Nagy and
  • László Makrai
  • + 2 authors

Extraintestinal pathogenic Escherichia coli (ExPEC) strains are capable of causing various systemic infections in both humans and animals. In this study, we isolated and characterized 30 E. coli strains from the parenchymatic organs and brains of you...

(This article belongs to the Section Infectious Diseases)
  • Article
  • Open Access
5 Citations
4,737 Views
23 Pages

A Perspective of the Epidemiology of Rabies in South Africa, 1998–2019

  • Ayla J. Malan,
  • Andre Coetzer,
  • Cayla Bosch,
  • Nicolette Wright and
  • Louis H. Nel

Despite the implementation of various control strategies aimed at eliminating canine-mediated rabies, the disease is still endemic in up to 150 countries across the world. Rabies remains endemic to South Africa, with various reservoir species (both w...

(This article belongs to the Section Infectious Diseases)
  • Article
  • Open Access
2 Citations
2,724 Views
12 Pages

Bulinus snails surviving drought play a key role in the seasonal transmission of urogenital schistosomiasis, although our knowledge of their adaptation to dry season is still limited. We investigated the survival dynamic and infestation by the Schist...

(This article belongs to the Section Neglected and Emerging Tropical Diseases)
  • Article
  • Open Access
1 Citations
3,706 Views
10 Pages

Tobacco Use Behaviors and Associated Factors among Newly Diagnosed Tuberculosis Patients in Benin and Burkina Faso

  • Abdoul R. Ouédraogo,
  • Arnauld A. Fiogbé,
  • Sonia Menon,
  • Marius Atchéni Esse,
  • Tandaogo Saouadogo,
  • Adam Daouda,
  • Adjima Combary,
  • Gildas Agodokpessi,
  • Georges Ouédraogo and
  • Kobto G. Koura
  • + 2 authors

The objective of this study was to assess tobacco use (TU) behaviors among newly diagnosed pulmonary TB (PTB) patients and identify associated factors in Benin and Burkina Faso. A cross-sectional study was conducted in 20 randomly selected TB clinics...

(This article belongs to the Section Infectious Diseases)
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Trop. Med. Infect. Dis. - ISSN 2414-6366