Global Perspectives on Kaposi’s Sarcoma-Associated Herpesvirus Infection

Dear Colleagues,

Kaposi’s sarcoma-associated herpesvirus (KSHV) presents a peculiar geographical epidemiology primarily burdening sub-Saharan Africa, areas in the Mediterranean, northwestern China and South American Amerindian populations, as well as subpopulations globally, such as men having sex with men (MSM) and persons living with HIV (PLWH). Risk for Kaposi’s sarcoma (KS) development, and other KSHV-related malignancies and syndromes, is highest amongst PLWH who are co-infected with KSHV, which in endemic areas likely takes place during childhood. KSHV, in the context of disease-precipitating factors, one of the most important of which being HIV-related immune suppression, can give rise to KS, multicentric Castleman disease (MCD), primary effusion lymphoma (PEL), and KSHV inflammatory cytokine syndrome (KICS), all of which pose diagnostic and treatment challenges, especially in resource-limited areas.  

This Special Issue, entitled “Global Perspectives on Kaposi's Sarcoma-Associated Herpesvirus Infection”, aims to bring together clinical science, case studies, basic science, and literature reviews addressing advances in our understanding of KSHV epidemiology, infection dynamics and prevention, pathogenesis, presentation of KSHV-related diseases, and treatment strategies. We particularly seek and encourage submissions from globally diverse areas in which KSHV may be highly prevalent but where research profiles may not be well known.

Dr. Melissa Blumenthal
Dr. Georgia Schäfer
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• KSHV
• herpesvirus
• Kaposi’s sarcoma
• HIV
• multicentric Castleman disease
• KICS
• primary effusion lymphoma
• AIDS
• oncogenic virus
• HAART