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Tropical Medicine and Infectious Disease, Volume 6, Issue 2

June 2021 - 67 articles

Cover Story: Following eradication of the principal vector, Rhodnius prolixus, in Central America, it was believed that incident vector-borne Chagas disease transmission risk was nominal. Our work identified a high burden in El Salvadorian children largely born after the eradication of this vector species. In addition, this investigation was the first to examine concomitant parasitic infections and malnutrition in the context of pediatric Chagas disease. Polyparasitism resulted in significantly higher overall parasitic burden, highlighting the value of expanded parasitic diagnostic panels. Further, malnutrition was extensive in this cohort. It is hypothesized that these frequent co-occurring conditions leads to a lower overall immunologic ability to fight off parasitic disease, yielding children at higher- risk for poor parasitic disease prognosis. View this paper
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Articles (67)

  • Review
  • Open Access
12 Citations
9,189 Views
12 Pages

Severe Odontogenic Infections during Pregnancy and Related Adverse Outcomes. Case Report and Systematic Literature Review

  • Resi Pucci,
  • Andrea Cassoni,
  • Daniele Di Carlo,
  • Marco Della Monaca,
  • Umberto Romeo and
  • Valentino Valentini

Odontogenic infections have the potential to develop into deep-space infections and may cause severe diseases with possible life-threatening complications. Dental infections during pregnancy require special attention in terms of possible complication...

  • Article
  • Open Access
28 Citations
8,873 Views
19 Pages

Extended Spectrum Beta-Lactamase Escherichia coli in River Waters Collected from Two Cities in Ghana, 2018–2020

  • Regina Ama Banu,
  • Jorge Matheu Alvarez,
  • Anthony J. Reid,
  • Wendemagegn Enbiale,
  • Appiah-Korang Labi,
  • Ebenezer D. O. Ansa,
  • Edith Andrews Annan,
  • Mark Osa Akrong,
  • Selorm Borbor and
  • Lady A. B. Adomako
  • + 10 authors

Infections by Extended-Spectrum Beta-Lactamase producing Escherichia coli (ESBL-Ec) are on the increase in Ghana, but the level of environmental contamination with this organism, which may contribute to growing Antimicrobial Resistance (AMR), is unkn...

  • Article
  • Open Access
14 Citations
7,355 Views
12 Pages

Larvicidal Activities against Aedes aegypti of Supernatant and Pellet Fractions from Cultured Bacillus spp. Isolated from Amazonian Microenvironments

  • Ricardo M. Katak,
  • Elerson M. Rocha,
  • Juan C. Oliveira,
  • Veranilce A. Muniz,
  • Marta R. Oliveira,
  • Francisco A. S. Ferreira,
  • William R. Silva,
  • Rosemary A. Roque,
  • Antonia Q. L. de Souza and
  • Jayme A. Souza-Neto
  • + 3 authors

The Aedes aegypti mosquito is the primary vector of Dengue, Chikungunya and Zika causing major problems for public health, which requires new strategies for its control, like the use of entomopathogenic microorganisms. In this study, bacteria from va...

  • Article
  • Open Access
5 Citations
6,598 Views
9 Pages

High Levels of Antibiotic Resistance Patterns in Two Referral Hospitals during the Post-Ebola Era in Free-Town, Sierra Leone: 2017–2019

  • Zikan Koroma,
  • Francis Moses,
  • Alexandre Delamou,
  • Katrina Hann,
  • Engy Ali,
  • Freddy Eric Kitutu,
  • Juliet Sanyu Namugambe,
  • Doris Harding,
  • Veerle Hermans and
  • Kudakwashe Takarinda
  • + 2 authors

The Post-Ebola era (2017–2019) presented an opportunity for laboratory investments in Sierra Leone. US CDC supported the Ministry of Health and Sanitation to establish a microbiological unit for routine antimicrobial sensitivity testing in two referr...

  • Article
  • Open Access
9 Citations
6,526 Views
15 Pages

Screening People with Tuberculosis for High Risk of Severe Illness at Notification: Programmatic Experience from Karnataka, India

  • Hemant Deepak Shewade,
  • Sharath Burugina Nagaraja,
  • Hosadurga Jagadish Deepak Murthy,
  • Basavarajachar Vanitha,
  • Madhavi Bhargava,
  • Anil Singarajipura,
  • Suresh G. Shastri,
  • Ramesh Chandra Reddy,
  • Ajay M. V. Kumar and
  • Anurag Bhargava

Due to limited availability of diagnostics and capacity, people with tuberculosis do not always undergo systematic assessment for severe illness (requiring inpatient care). In Karnataka (south India), para-medical programme staff used a screening too...

  • Article
  • Open Access
26 Citations
6,470 Views
10 Pages

Natural Infection and Vertical Transmission of Zika Virus in Sylvatic Mosquitoes Aedes albopictus and Haemagogus leucocelaenus from Rio de Janeiro, Brazil

  • Jeronimo Alencar,
  • Cecilia Ferreira de Mello,
  • Carlos Brisola Marcondes,
  • Anthony Érico Guimarães,
  • Helena Keiko Toma,
  • Amanda Queiroz Bastos,
  • Shayenne Olsson Freitas Silva and
  • Sergio Lisboa Machado

Zika virus (ZIKV) was recently introduced into the Western Hemisphere, where it is suspected to be transmitted mainly by Aedes aegypti in urban environments. ZIKV represents a public health problem as it has been implicated in congenital microcephaly...

  • Article
  • Open Access
9 Citations
7,100 Views
12 Pages

Low Prevalence of Cysticercosis and Trichinella Infection in Pigs in Rural Cambodia

  • Rebecca Söderberg,
  • Johanna Frida Lindahl,
  • Ellinor Henriksson,
  • Kang Kroesna,
  • Sokong Ly,
  • Borin Sear,
  • Fred Unger,
  • Sothyra Tum,
  • Hung Nguyen-Viet and
  • Gunilla Ström Hallenberg

Cysticercosis and Trichinella spp. infection are parasitic zoonoses prevalent among pigs in Southeast Asia, where pork is the most important source of meat. In rural Cambodia, many pigs are raised extensively in family backyards, and information rega...

  • Article
  • Open Access
8 Citations
7,289 Views
16 Pages

Modeling the Cost-Effectiveness of Interventions to Prevent Plague in Madagascar

  • Giovanni S. P. Malloy,
  • Margaret L. Brandeau and
  • Jeremy D. Goldhaber-Fiebert

Plague (Yersinia pestis) remains endemic in certain parts of the world. We assessed the cost-effectiveness of plague control interventions recommended by the World Health Organization with particular consideration to intervention coverage and timing....

  • Article
  • Open Access
42 Citations
10,762 Views
18 Pages

Evolution of Rabies in South America and Inter-Species Dynamics (2009–2018)

  • Mauro Meske,
  • Angela Fanelli,
  • Felipe Rocha,
  • Lina Awada,
  • Paula Caceres Soto,
  • Neo Mapitse and
  • Paolo Tizzani

Rabies is listed as one of the World Health Organisation’s (WHO) Neglected Tropical Diseases Worldwide, with a significant impact in South America. This paper explores the dynamics of rabies cases in humans, pets (dogs and cats), livestock and wildli...

  • Perspective
  • Open Access
9 Citations
6,640 Views
13 Pages

Real-Time Operational Research: Case Studies from the Field of Tuberculosis and Lessons Learnt

  • Anthony D. Harries,
  • Pruthu Thekkur,
  • Irene Mbithi,
  • Jeremiah Muhwa Chakaya,
  • Hannock Tweya,
  • Kudakwashe C. Takarinda,
  • Ajay M. V. Kumar,
  • Srinath Satyanarayana,
  • Selma Dar Berger and
  • I. D. Rusen
  • + 2 authors

Real-time operational research can be defined as research on strategies or interventions to assess if they are feasible, working as planned, scalable and effective. The research involves primary data collection, periodic analysis during the conduct o...

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Trop. Med. Infect. Dis. - ISSN 2414-6366Creative Common CC BY license