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Tropical Medicine and Infectious Disease, Volume 10, Issue 2

February 2025 - 30 articles

Cover Story: Schistosomiasis in the Philippines, caused by the blood fluke Schistosoma japonicum, persists despite decades of preventative chemotherapy. The parasite’s life cycle involves a snail intermediate host and 46 potential mammalian definitive hosts, contributing to a complex epidemiology influenced by environmental, socioeconomic and biological factors. The control and eventual elimination of S. japonicum requires management of these animal hosts and new interventions for the human hosts, including health education and water, sanitation, and the hygiene (WASH) infrastructure. In this review, we examine the status and epidemiology of S. japonicum in the Philippines with an overview of the current control program and what needs to be accomplished to control and eliminate this disease in the country. View this paper
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Articles (30)

  • Article
  • Open Access
2 Citations
4,617 Views
16 Pages

Background: Aedes species transmit arboviral diseases, such as dengue, chikungunya, yellow fever, and Zika. The diseases cause severe sickness, mortality, and economic losses. This study describes the biting hour and host-seeking behavior of Ae. aegy...

  • Case Report
  • Open Access
1 Citations
2,199 Views
11 Pages

Central Nervous System Infection by Free-Living Nematode Cephalobus cubaensis in a Human Host in Africa

  • Charlotte Sriruttan-Nel,
  • Chelline Cairns,
  • Shareen Boughan,
  • Bhavani Moodley,
  • Lisa Ming Sun,
  • Wai Yin Chan,
  • Arshad Ismail,
  • Absalom Mwazha,
  • Praniel Bennimahadeo and
  • Nithendra Manickchund
  • + 6 authors

Background: Human central nervous system infections due to free-living nematodes, although extremely rare, are usually fatal. Immunodeficiency has not been a feature of most of these cases, unlike the situation pertaining to disseminated Strongyloide...

  • Article
  • Open Access
1 Citations
3,373 Views
9 Pages

Human papillomavirus (HPV) infection is one of the most common sexually transmitted infections in all genders worldwide. Its association with male infertility is deeply investigated, although there are conflicting data on the role of the virus in the...

  • Brief Report
  • Open Access
1 Citations
2,113 Views
11 Pages

Wide Variation of Aedes albopictus Genotypes First Introduced into Canary Islands Assessed by rDNA Internal Transcribed Spacer Region and mtDNA cox1 Sequencing and Cloning

  • Alejandra De Elías-Escribano,
  • Irene Serafín-Pérez,
  • Patricio Artigas,
  • Carolina Fernández-Serafín,
  • Sara Rodríguez-Camacho,
  • Beatriz Yanes-Manrique,
  • Víctor González-Alonso,
  • Santiago Mas-Coma,
  • Jacob Lorenzo-Morales and
  • María Dolores Bargues

Aedes albopictus, one of the most rapidly spreading invasive mosquito species, has expanded from Asia to establish populations on every continent except Antarctica, showcasing exceptional adaptability, particularly in island environments. This study...

  • Article
  • Open Access
1,996 Views
12 Pages

Epidemiological Dynamics and Trends of Dengue Outbreaks in Sao Tome and Principe: A Comprehensive Retrospective Analysis (2022–2024)

  • Sousa Lazaro,
  • Vilfrido Santana Gil,
  • Ivando Carvalho Viegas de Ceita,
  • Isaulina Neto Viegas Barreto,
  • Eula Carvalho Batista Sousa Maquengo,
  • Andreza Batista de Sousa,
  • Bakissy da Costa Pina,
  • Tieble Traore,
  • Alimuddin Zumla and
  • John Otokoye Otshudiema

Background: Dengue has emerged as a significant public health concern in Sao Tome and Principe, with the first documented outbreak occurring between 2022 and 2024. This study examined the epidemiological patterns, environmental determinants, and demo...

  • Article
  • Open Access
1,532 Views
10 Pages

Viruses are a frequent cause of self-limited diarrhea, with more severe outcomes in immunocompromised patients. This study aimed to compare the performance of Real-Time RT-PCR to chromatographic immunoassays (CIAs) for detecting the major gastrointes...

  • Systematic Review
  • Open Access
1 Citations
3,043 Views
14 Pages

Molecular Detection of Mycobacterium leprae and the Process of Infection and Illness in Contacts of Leprosy Patients: A Systematic Review

  • Sarah Lamas Vidal,
  • Lavínia Cássia Ferreira Batista,
  • Daniele dos Santos Lages,
  • Bruna Eduarda Bortolomai,
  • Isabela de Caux Bueno,
  • Eyleen Nabyla Alvarenga Niitsuma,
  • Nathan Guilherme de Oliveira,
  • Ida Maria Foschiani Dias Baptista and
  • Francisco Carlos Félix Lana

Various techniques have been used for the molecular identification of Mycobacterium leprae (M. leprae). The aim of this review was to identify the relationship between the molecular presence of M. leprae and the process of infection and/or illness of...

  • Article
  • Open Access
2 Citations
1,667 Views
13 Pages

Transcriptome Analysis of Culex pipiens quinquefasciatus Larvae Exposed to a Semi-Lethal Dose of Vermistatin

  • Junhui Chen,
  • Zhiyong Xu,
  • Feiying Yang,
  • Jian Yang,
  • Wendong Kuang,
  • Jianghuai Li,
  • Yaqi Wang and
  • Liang Jin

Culex pipiens quinquefasciatus is a notorious vector transmitting severe diseases such as Zika virus and West Nile virus to humans worldwide. Vermistatin is a type of funicon-like compound and was first isolated from Penicillin vermiculatum in the 19...

  • Brief Report
  • Open Access
3,219 Views
11 Pages

A Retrospective Study of Clinical Biomarkers of Severe Dengue in a Tertiary Hospital in Johor Bahru, Malaysia

  • Si Yin Kok,
  • Ruth Elizabeth Abraham,
  • Shareen Nisha Jauhar Ali,
  • Wei Xuan Tuang and
  • Edmund Liang Chai Ong

Management of severe dengue remains a clinical challenge. This retrospective study evaluated clinical features and laboratory biomarkers associated with severe dengue at Hospital Sultanah Aminah Johor Bahru from 1 January 2022 to 31 March 2023. Recor...

  • Review
  • Open Access
7 Citations
25,001 Views
30 Pages

Schistosomiasis in the Philippines: A Comprehensive Review of Epidemiology and Current Control

  • Emmanuel John Tabilin,
  • Darren J. Gray,
  • Mario A. Jiz,
  • Mary Lorraine Mationg,
  • Marianette Inobaya,
  • Eleonor Avenido-Cervantes,
  • Megumi Sato,
  • Marcello Otake Sato,
  • Yasuhito Sako and
  • Yi Mu
  • + 4 authors

Schistosomiasis japonica is an infectious parasitic disease caused by infection with the blood fluke Schistosoma japonicum, which is endemic in China, small pockets of Indonesia, and the Philippines. Of the three countries, the prevalence of infectio...

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Trop. Med. Infect. Dis. - ISSN 2414-6366