- 3.0Impact Factor
- 7.4CiteScore
- 24 daysTime to First Decision
Non-Coding RNA, Volume 10, Issue 4
August 2024 - 9 articles
Cover Story: We have developed a novel amplification-free analytical platform to detect and quantify microRNA cancer biomarkers at concentration levels found in liquid biopsies and at approximately +/−20% accuracy across all concentrations. This platform uses total RNA isolated from the biospecimen as the microRNA source and the MinION nanopore device from Oxford Nanopore Technologies (ONT) for sensing. Detection and quantification of the target microRNA are enabled by a complementary oligo probe enhanced with osmium tags. Copies of microRNA cancer biomarkers show approximate 1.8-fold overexpression, with no data overlap between healthy and cancer samples. Once microRNA copies are normalized to the same total RNA content, they appear independent of the biospecimen, suggesting that urine may replace blood withdrawal. View this paper
- Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
- You may sign up for email alerts to receive table of contents of newly released issues.
- PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.
Articles
There are no articles in this issue yet.
Get Alerted
Add your email address to receive forthcoming issues of this journal.
Non-Coding RNA - ISSN 2311-553X