Bioengineering, Volume 8, Issue 3 (March 2021) – 12 articles
Cover Story (view full-size image): CO2 removal via membrane oxygenators has become an important clinical technique. In order to further optimize oxygenators, accurate prediction of the CO2 removal rate is required. It can be determined either by measuring the CO2 content in the exhaust gas of the oxygenator (sweep flow-based) or by using blood gas analyzer data and a CO2 solubility model (blood-based). In this study, we determined the CO2 removal rate of an oxygenator by using both methods in in vitro experiments with bovine blood, as well as in in vivo experiments with porcine blood. This allows direct comparison and evaluation of the two methods. Furthermore, the suitability of four unique CO2 solubility models, with different levels of complexity, was investigated. View this paper
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