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Dermatopathology, Volume 9, Issue 3

2022 September - 13 articles

Cover Story: Melanocytic neoplasms in Asia are characterized by a predominance of acral melanocytic nevus and acral melanoma, which occur frequently on the sole and nails. Anatomic mapping shows that acral melanomas occur mostly on the weight-bearing portion of the sole, whereas acral melanocytic nevi on the arch area of the sole. Acral melanomas appear as large irregular black patches on the heel. Dermoscopy is a useful diagnostic tool for the differential diagnosis and reveals parallel ridge pattern on acral melanoma with a parallel furrow pattern on the acral melanocytic nevus. Histopathologic examination shows lentiginous proliferation of atypical melanocytes in the epidermal basal layer in the very early stages of acral lentiginous melanoma. Immunohistochemical staining such as HMB45 and Melan-A highlights prominent dendritic processes of melanoma cells in the epidermis. View this paper
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Articles (13)

  • Article
  • Open Access
10 Citations
5,383 Views
14 Pages

Cutaneous Involvement of Extranodal NK/T Cell Lymphoma, Nasal Type, a Clinical and Histopathological Mimicker of Various Skin Diseases

  • Preeyawat Ngamdamrongkiat,
  • Sanya Sukpanichnant,
  • Manasmon Chairatchaneeboon,
  • Archrob Khuhapinant and
  • Panitta Sitthinamsuwan

Background: Extranodal NK/T cell lymphoma, nasal type (ENK/T) with cutaneous involvement has various histopathological findings and diverse clinical manifestations. Methods: A retrospective study of cutaneous involvement of ENK/T lymphoma between 200...

(This article belongs to the Special Issue Dermatopathology in Asia)
  • Review
  • Open Access
20 Citations
26,874 Views
12 Pages

Acral melanocytic neoplasms, including acral melanocytic nevus and acral melanoma, are common melanocytic lesions in Asian populations. Both lesions occur on the volar surface of the hands and feet, and on nail units. Acral melanocytic nevi occur on...

(This article belongs to the Special Issue Dermatopathology in Asia)
  • Case Report
  • Open Access
2 Citations
3,541 Views
5 Pages

A Case of IgG and IgA Anti-Laminin-332 Antibody-Positive Mucous Membrane Pemphigoid with IgG and IgA Anti-Envoplakin and Anti-Periplakin Antibodies

  • Yoshiaki Matsushima,
  • Masako Kitano,
  • Daisuke Hayashi,
  • Hiroyuki Goto,
  • Mako Mine,
  • Takeshi Yokoe,
  • Makoto Kondo,
  • Koji Habe,
  • Yuji Toiyama and
  • Keiichi Yamanaka
  • + 3 authors

A 76-year-old Japanese man presented with a 6-year history of a sore throat. He was treated at several clinics without any improvement before being referred to us. Physical examination revealed widespread erosions and ulcers from the palate to the la...

  • Case Report
  • Open Access
2 Citations
5,550 Views
5 Pages

We report on the appearance of multiple tense blisters surrounding the exit site of a Tenckhoff catheter in a 79-year-old woman with end-stage renal disease in peritoneal dialysis. The differential diagnoses included a contact allergic or irritative...

(This article belongs to the Special Issue In Memory of Raffaele Gianotti)
  • Case Report
  • Open Access
8 Citations
4,182 Views
5 Pages

Folliculosebaceous cystic hamartoma (FSCH) is an uncommon hamartoma that usually presents on the central face area of adults as an asymptomatic, solitary dome-shaped or pedunculated papule. We report a case of a 35-year-old female who presented with...

  • Case Report
  • Open Access
5,622 Views
6 Pages

Large Lobular Capillary Hemangioma Associated with Ingrown Toenail: Histopathological Features and Case Report

  • Antonio Córdoba-Fernández,
  • María Dolores Jiménez-Cristino and
  • Victoria Eugenia Córdoba-Jiménez

Lobular capillary hemangioma (LCH-PG) is a type of pyogenic granuloma characterized by proliferating blood vessels that resemble conventional granulation tissue. Granulation tissue is very often seen in association with ingrown toenails. Despite the...

  • Case Report
  • Open Access
2 Citations
5,289 Views
13 Pages

Kaposi Sarcoma in Afghanistan: A Case Series from a Tertiary Referral Center

  • Alyssa D. Higgins,
  • Richard J. Dunn,
  • Omer Malikzai,
  • Mirwais Ahmadzai,
  • Jerad M. Gardner,
  • Benjamin K. Stoff and
  • Josette R. McMichael

Kaposi sarcoma is a vascular endothelial neoplasm caused by human herpesvirus 8. Although it is a well-studied disease, little is known about the specific characteristics or epidemiology of Kaposi sarcoma in Afghanistan. The data consist primarily of...

  • Systematic Review
  • Open Access
23 Citations
9,805 Views
7 Pages

Histopathology of Hidradenitis Suppurativa: A Systematic Review

  • Shane David Basil Smith,
  • Ginette A. Okoye and
  • Olayemi Sokumbi

Hidradenitis suppurativa (HS) is a chronic inflammatory scarring disease felt to be related to occlusion of the hair follicle unit in intertriginous areas. We perform a systematic review on HS histopathology to evaluate current knowledge and discuss...

  • Case Report
  • Open Access
7 Citations
13,764 Views
7 Pages

Pityriasis Lichenoides et Varioliformis Acuta as a Complication of COVID-19 Infection

  • Henriette De La Garza,
  • Elie Saliba,
  • Monica Rosales Santillan,
  • Candice Brem and
  • Neelam A. Vashi

Pityriasis lichenoides is an acute and/or chronic skin disease associated with recurrent erythematous papules that self-resolve. While its etiology is unknown, preceding viral infection may play a role. We present an atypical case of a 40-year-old wo...

  • Review
  • Open Access
14 Citations
17,440 Views
32 Pages

The Impact of COVID-19 Pandemic on Dermatological Conditions: A Novel, Comprehensive Review

  • Gehan A. Pendlebury,
  • Peter Oro,
  • William Haynes,
  • Drew Merideth,
  • Samantha Bartling and
  • Michelle A. Bongiorno

Background: The earliest cases of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China, in December 2019. Since the declaration as a pandemic on 11 March 2020, further dermatological conditions continue to be documente...

  • Case Report
  • Open Access
5 Citations
6,138 Views
5 Pages

Cocaine/Levamisole-Induced, Skin-Limited ANCA-Associated Vasculitis with Pyoderma Gangrenosum-like Presentation

  • Mirjana Urosevic-Maiwald,
  • Jan-Hendrik B. Hardenberg,
  • Jürg Hafner and
  • Marie-Charlotte Brüggen

The use of levamisole as the most frequent adulterant of cocaine has merged in previously unknown toxicities, notably a disease entity called cocaine/levamisole-associated autoimmune syndrome (CLAAS). Clinically, CLAAS can manifest with diverse cutan...

(This article belongs to the Section Clinico-Pathological Correlation in Dermatopathology)
  • Case Report
  • Open Access
1 Citations
4,694 Views
4 Pages

Pseudo-Pemphigoid Gestationis Eruption Following SARS-CoV-2 Vaccination with mRNA Vaccine

  • Caroline de Lorenzi,
  • Gürkan Kaya and
  • Laurence Toutous Trellu

Auto-immune reactions, including auto-immune bullous disease, have been reported following SARS-CoV-2 virus vaccination. Few cases of bullous pemphigoid are described, but there has been no case of pemphigoid gestationis. We report the first case here.

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Dermatopathology - ISSN 2296-3529