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Journal of Developmental Biology, Volume 2, Issue 1

March 2014 - 4 articles

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Articles (4)

  • Review
  • Open Access
5 Citations
14,113 Views
16 Pages

21 March 2014

Vitamin A has been shown to be essential for a multitude of biological processes vital for mammalian development and homeostasis. Its active metabolite, retinoic acid (RA), is important for establishing and maintaining proper germ cell development. D...

  • Review
  • Open Access
18 Citations
14,449 Views
22 Pages

Retinoids and Cardiac Development

  • Stéphane Zaffran,
  • Nicolas El Robrini and
  • Nicolas Bertrand

21 March 2014

Retinoic acid (RA), a derivative of vitamin A, is involved in signal transduction during vertebrate organogenesis. Retinoids through binding to nuclear receptors called RA receptors (RARs) and retinoid X receptors (RXRs) regulate various processes du...

  • Review
  • Open Access
3 Citations
14,905 Views
16 Pages

Signaling by Retinoic Acid in Embryonic and Adult Hematopoiesis

  • Elena Cano,
  • Laura Ariza,
  • Ramón Muñoz-Chápuli and
  • Rita Carmona

17 March 2014

Embryonic and adult hematopoiesis are both finely regulated by a number of signaling mechanisms. In the mammalian embryo, short-term and long-term hematopoietic stem cells (HSC) arise from a subset of endothelial cells which constitute the hemogenic...

  • Review
  • Open Access
34 Citations
10,431 Views
17 Pages

The Epicardium and the Development of the Atrioventricular Junction in the Murine Heart

  • Marie M. Lockhart,
  • Aimee L. Phelps,
  • Maurice J. B. Van den Hoff and
  • Andy Wessels

4 March 2014

Insight into the role of the epicardium in cardiac development and regeneration has significantly improved over the past ten years. This is mainly due to the increasing availability of new mouse models for the study of the epicardial lineage. Here we...

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J. Dev. Biol. - ISSN 2221-3759