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Open AccessReview

Anticancer Potential of Lichens’ Secondary Metabolites

1
Department of Pharmacology, Faculty of Medicine, P.J. Šafárik University in Košice, 040 01 Košice, Slovakia
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Department of Obstetrics and Gynecology, Jessenius Faculty of Medicine, Comenius University in Bratislava, 036 01 Martin, Slovakia
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Department of Medical Biology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 01 Martin, Slovakia
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Department of Experimental Carcinogenesis, Biomedical Centre Martin, Division of Oncology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 036 01 Martin, Slovakia
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Weill Cornell Medicine in Qatar, Qatar Foundation-Education City, Doha 24144, Qatar
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Department of Medical Biology, Faculty of Medicine, P.J. Šafárik University in Košice, 040 01 Košice, Slovakia
*
Author to whom correspondence should be addressed.
Biomolecules 2020, 10(1), 87; https://doi.org/10.3390/biom10010087
Received: 25 November 2019 / Revised: 31 December 2019 / Accepted: 3 January 2020 / Published: 5 January 2020
Lichens produce different classes of phenolic compounds, including anthraquinones, xanthones, dibenzofuranes, depsides and depsidones. Many of them have revealed effective biological activities such as antioxidant, antiviral, antibiotics, antifungal, and anticancer. Although no clinical study has been conducted yet, there are number of in vitro and in vivo studies demonstrating anticancer effects of lichen metabolites. The main goal of our work was to review most recent published papers dealing with anticancer activities of secondary metabolites of lichens and point out to their perspective clinical use in cancer management. View Full-Text
Keywords: lichen; secondary metabolites; anticancer; in vitro; in vivo lichen; secondary metabolites; anticancer; in vitro; in vivo
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MDPI and ACS Style

Solárová, Z.; Liskova, A.; Samec, M.; Kubatka, P.; Büsselberg, D.; Solár, P. Anticancer Potential of Lichens’ Secondary Metabolites. Biomolecules 2020, 10, 87.

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