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Scientia Pharmaceutica
  • Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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18 May 2002

The Behaviour of Arylidene Barbituric Acid and Cyclohexadione Derivatives Towards Tris(dimethy1amino)phosphin

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and
1
National Research Center, Cairo, Egypt
2
Agriculture Research Center, Cairo, Egypt
*
Author to whom correspondence should be addressed.

Abstract

Tris(dimethy1amino)phosphine 1 reacted with phenylarylidene barbituric acids 4 to yield the triaminophosphonium dipolar ion adduct 7. 2-Arylidene-1,3- cyclohexanedione 5 and 2-Arylidene-5,5-dimethylcyclohaxane1-,3 -diones 6 reacted with phosphine 1 to produce the dioxyxanthenes 10 and 12, respectively. Structural assignments are based on analytical, chemical, and spectroscopic evidences. A mechanism is proposed to explain the formation of these compounds. The biological acitivity of the new synthesized compounds against Aphis Craccivora, a serious pest infecting many crops in Egypt, was studied.

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