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Review

Gastric Cancer Due to Chronic H. pylori Infection: What We Know and Where We Are Going

by
Patrick Joseph Tempera
1,*,
Mark Michael
1,
Omar Tageldin
2 and
Stephen Hasak
2
1
Department of Internal Medicine, Albany Medical Center, Albany, NY 12208, USA
2
Department of Gastroenterology, Albany Medical Center, Albany, NY 12208, USA
*
Author to whom correspondence should be addressed.
Diseases 2022, 10(3), 57; https://doi.org/10.3390/diseases10030057
Submission received: 25 April 2022 / Revised: 21 August 2022 / Accepted: 24 August 2022 / Published: 25 August 2022
(This article belongs to the Special Issue Gastrointestinal Tract Inflammation and Cancers)
Review Reports Versions Notes

Abstract

Helicobacter pylori is an established cause of many gastrointestinal pathologies including peptic ulcer disease, gastritis, and gastric cancer. It is an entity that affects the global population, and its true nature has only been known since the 1980s. Although there is much known about H. pylori including its pathophysiology, detection, and eradication, resistance to current therapy models is common. This is problematic because untreated or inadequately treated H. pylori increases morbidity and mortality related to gastric cancer and peptic ulcer disease among others. In order to improve the treatment and reduce resistance, there is significant ongoing research identifying new detection and eradication methods for H. pylori. This review aims to highlight what has already been established regarding H. pylori’s epidemiology, pathophysiology, detection, and treatment as well as the most current and novel research involving detection and treatment of H. pylori.
Keywords: Helicobacter pylori; carcinogenesis; gastric cancer; therapeutic advancements; novel therapies Helicobacter pylori; carcinogenesis; gastric cancer; therapeutic advancements; novel therapies

Share and Cite

MDPI and ACS Style

Tempera, P.J.; Michael, M.; Tageldin, O.; Hasak, S. Gastric Cancer Due to Chronic H. pylori Infection: What We Know and Where We Are Going. Diseases 2022, 10, 57. https://doi.org/10.3390/diseases10030057

AMA Style

Tempera PJ, Michael M, Tageldin O, Hasak S. Gastric Cancer Due to Chronic H. pylori Infection: What We Know and Where We Are Going. Diseases. 2022; 10(3):57. https://doi.org/10.3390/diseases10030057

Chicago/Turabian Style

Tempera, Patrick Joseph, Mark Michael, Omar Tageldin, and Stephen Hasak. 2022. "Gastric Cancer Due to Chronic H. pylori Infection: What We Know and Where We Are Going" Diseases 10, no. 3: 57. https://doi.org/10.3390/diseases10030057

APA Style

Tempera, P. J., Michael, M., Tageldin, O., & Hasak, S. (2022). Gastric Cancer Due to Chronic H. pylori Infection: What We Know and Where We Are Going. Diseases, 10(3), 57. https://doi.org/10.3390/diseases10030057

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