Next Article in Journal
Investigation Utilizing the HLB Concept for the Development of Moisturizing Cream and Lotion: In-Vitro Characterization and Stability Evaluation
Next Article in Special Issue
Inhibitory Effect of Manassantin B Isolated from Saururus chinensis on Skin Heat Aging
Previous Article in Journal
Cosmetic Use-Related Adverse Events: Findings from Lay Public in Malaysia
Previous Article in Special Issue
Broussonetia papyrifera Promotes Hair Growth Through the Regulation of β-Catenin and STAT6 Target Proteins: A Phototrichogram Analysis of Clinical Samples
Open AccessArticle

Solid Lipid Nanoparticles (SLNs) with Potential as Cosmetic Hair Formulations Made from Otoba Wax and Ultrahigh Pressure Homogenization

1
Programa de Maestría en Formulación de Productos Químicos y Derivados, Facultad de Ciencias Naturales, Universidad Icesi, Calle 18 No. 122–135, Cali 76003, Colombia
2
Laboratorio de Diseño y Formulación de Productos Químicos y Derivados, Departamento de Ciencias Farmacéuticas, Facultad de Ciencias Naturales, Universidad Icesi, Calle 18 No. 122–135, Cali 76003, Colombia
3
Centro de Ingredientes Naturales Especializados y Biotecnológicos (CINEB), Facultad de Ciencias Naturales, Universidad Icesi, Calle 18 No. 122–135, Cali 76003, Colombia
*
Author to whom correspondence should be addressed.
Cosmetics 2020, 7(2), 42; https://doi.org/10.3390/cosmetics7020042
Received: 13 May 2020 / Revised: 27 May 2020 / Accepted: 2 June 2020 / Published: 4 June 2020
The development and physicochemical characterization of solid lipid nanoparticles (SLNs) with potential for formulating hair cosmetic products were carried out. SLNs were made from Otoba wax, which is native to the tropical Andean region and has a high chemical composition of fatty acids with intermediate chains. SLNs were formulated by preparing wax-in-water dispersions at two internal phase proportions (low = 5% w/w and high = 20% w/w), using the same ratio of surfactant system and preservatives. The coarse dispersions were subjected to ultrahigh pressure homogenization (UHPH), and thermal stability assays for 4 weeks were carried out, where changes in Creaming Index, droplet size, polydispersity, viscosity, zeta potential, conductivity, and pH were evaluated. The results showed that Otoba wax has a required HLB value around 9 and is mainly composed of lauric (~35%) and myristic (~45%), which have been reported to improve the condition of hair loss. Regarding the development on SLNs, it was found that the internal phase concentration did not considerably affect the physicochemical and microbiological properties. Likewise, it was found that UHPH enabled the production of SLNs with particle sizes <200 nm, low polydispersity (<0.3), high zeta potential values, and suitable physical and microbiological stability. Therefore, Otoba wax has potential for the development of SLNs applicable to cosmetic formulations, especially for hair products. View Full-Text
Keywords: hair cosmetic formulations; Otoba wax; solid lipid nanoparticles (SLNs), thermal stability assay; ultrahigh pressure homogenization (UHPH) hair cosmetic formulations; Otoba wax; solid lipid nanoparticles (SLNs), thermal stability assay; ultrahigh pressure homogenization (UHPH)
Show Figures

Graphical abstract

MDPI and ACS Style

Rubiano, S.; Echeverri, J.D.; Salamanca, C.H. Solid Lipid Nanoparticles (SLNs) with Potential as Cosmetic Hair Formulations Made from Otoba Wax and Ultrahigh Pressure Homogenization. Cosmetics 2020, 7, 42.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop