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Open AccessArticle

Investigation Utilizing the HLB Concept for the Development of Moisturizing Cream and Lotion: In-Vitro Characterization and Stability Evaluation

1
Research & Development, Jamjoom Pharmaceuticals, Jeddah 21442, Saudi Arabia
2
Department of Pharmaceutics, College of Pharmacy, Najran University, Najran 11001, Saudi Arabia
*
Author to whom correspondence should be addressed.
Cosmetics 2020, 7(2), 43; https://doi.org/10.3390/cosmetics7020043
Received: 30 April 2020 / Revised: 23 May 2020 / Accepted: 30 May 2020 / Published: 5 June 2020
(This article belongs to the Special Issue Feature Papers in Cosmetics in 2020)
The current study aims to utilize the concept of the hydrophilic–lipophilic balance (HLB) value of ingredients for the development of a stable emulsion-based moisturizing cream and lotion for cosmetic application. The combination of a hydrophilic and lipophilic emulsifier such as glyceryl stearate (HLB value 3.8) and PEG-100 stearate (HLB value 18.8) were found to be effective to emulsify the chosen oil phase system at a specific concentration to achieve the required HLB for the development of the stable emulsion-based system. The developed formulation was characterized for pH, viscosity, spreadability, rheology, and droplet morphology. The influence of carbopol® ETD 2020 and the concentration of the oil phase on the rheology of the product was investigated and found to be significant to achieve the required thickening to convert the lotion into a cream. The formulation system developed through utilizing the concept of HLB was compared to a product developed through the conventional approach. It was observed that the utilization of the HLB method for the development of an emulsion-based product is a promising strategy compared to the conventional method. The physical stability and thermodynamic stability tests were carried out under different storage conditions. It was observed that the developed formulation was able to retain its integrity without showing any signs of instability during storage. View Full-Text
Keywords: moisturizer; cream/lotion; cosmetics; HLB value; rheology; stabilit moisturizer; cream/lotion; cosmetics; HLB value; rheology; stabilit
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MDPI and ACS Style

Alam, S.; Algahtani, M.S.; Ahmad, M.Z.; Ahmad, J. Investigation Utilizing the HLB Concept for the Development of Moisturizing Cream and Lotion: In-Vitro Characterization and Stability Evaluation. Cosmetics 2020, 7, 43.

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