2026 July-2 - 123 articles
The flower color of Michelia odora, an important landscape tree plant, shows significant ornamental value, but its regulatory mechanisms remain to be further explored. The present work integrated metabolomic with transcriptomic analyses for elucidati...
Growth traits, as core economic indicators in pig breeding, are closely associated with production costs, rearing duration, and final carcass quality and have thus consistently been a major focus of genetic improvement. This study aimed to identify c...
Bovine-associated Klebsiella pneumoniae is an important bacterial species linking animal health, microbial ecology, and One Health-oriented antimicrobial resistance research. In this study, we performed a global genomic analysis of 1291 publicly avai...
The WZS minipig, native to the Hainan province of China, is characterized by excellent meat palatability. In addition, this breed represents a promising animal model for human disease research, especially for cardiac diseases. Whole-genome resequenci...
Attention-Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder characterized by inattention, hyperactivity, and impulsivity. This study used high-temporal-resolution event-related potentials (ERPs) to investigate visuospatial attent...
Constipation is a prevalent gastrointestinal disorder with limited effective therapeutic options. Probiotics have emerged as promising microecological interventions, yet marked strain-specific efficacy and incomplete mechanistic understanding hinder...
Urbanization imposes multiple environmental stressors on urban rivers. Zooplankton are sensitive to environmental disturbances, making them useful tools for assessing ecological health and revealing river degradation processes. We surveyed the urban...
Ruminants are unique among living mammals in possessing paired bony cranial appendages in the form of horns, pronghorns, antlers, or ossicones. This review summarizes current knowledge on the structure, development, function, and evolution of these a...
Flowering time is a key adaptive trait in common vetch (Vicia sativa L.), influencing crop adaptation, yield potential, and forage quality. Despite its importance, the genetic basis of flowering in this species remains poorly understood. In this stud...
Maternal exposure to nanoplastics is a growing concern, but its effects on offspring cardiac development and the relative importance of prenatal and lactational exposure remain unclear. Pregnant C57BL/6J mice were orally exposed to 50 nm polystyrene...
Circulating tumor DNA (ctDNA) has emerged as a promising minimally invasive biomarker in multiple myeloma (MM), providing dynamic insight into tumor burden, clonal evolution and molecular heterogeneity. Unlike conventional bone marrow-based diagnosti...
Mitochondrial distribution and activity are closely associated with cytoplasmic maturation and developmental competence in mammalian oocytes; however, limited information is available regarding these processes in Vicugna pacos. This study aimed to ch...
Horse mesenteric fat is a culturally significant and nutritionally valuable food product in Central Asia, yet the kinetics of its oxidative and hydrolytic deterioration under sub-optimal storage conditions remain poorly characterized. Raw mesenteric...
Large-scale genomic initiatives like the UK Biobank have revolutionized our understanding of human disease. These studies typically assume that blood-derived DNA faithfully reflects an individual’s germline genome. However, this assumption is c...
Spinal cord injury often causes persistent neurological dysfunction, whereas the developing central nervous system retains greater plasticity. This study investigated whether spontaneous hindlimb motor recovery occurs after complete spinal cord trans...
Specialized pro-resolving mediators (SPMs) are endogenous lipid mediators that actively orchestrate the resolution of inflammation rather than relying solely on broad suppression of inflammatory signaling. At the ocular surface, lipoxins, resolvins,...
Dengue fever, a rapidly spreading mosquito-borne viral disease, poses a major global health issue, particularly in tropical and subtropical regions. The absence of a universally effective vaccine against all four dengue virus serotypes necessitates c...
The anuran atlas represents one of the most structurally simplified cervical systems among tetrapods, consisting of a single vertebra that must simultaneously support the head, permit mobility, and withstand mechanical loads generated during locomoti...
The Asian green mussel Perna viridis is expanding across coastal systems of the Americas, creating demand for curated molecular references to support biosecurity, aquaculture monitoring, and comparative invasion studies. Here, we report the first com...
Soil meso- and micro-fauna are key components of forest soil ecosystems, but the effects of converting natural forests to monoculture or mixed plantations on their communities remain unclear. This study compared soil meso- and micro-fauna communities...
The liver ranks among the peripheral organs exhibiting the most robust circadian rhythmicity, with glucose homeostasis, lipid metabolism, and bile acid turnover governed by tightly phased diurnal oscillations. Mitochondria execute these programs, the...
Fenugreek is a legume that has been used since ancient times to treat certain conditions. Numerous studies have examined the seed’s composition in terms of trigonelline, diosgenin and galactomannans, and their implications for nutrition and med...
Global climate change has amplified both the frequency and severity of abiotic stresses including drought, salinity and extreme temperatures, while concurrently modifying pathogen population dynamics, thereby imposing unparalleled threats to agricult...
High-temperature stress poses a critical challenge to cold-water aquaculture; however, the size-associated molecular mechanisms underlying thermal adaptation in triploid rainbow trout (Oncorhynchus mykiss) remain poorly understood. Here, we integrate...
The purpose of this experiment is to investigate the differences in blood gas indicators, antioxidant indicators, and lactate content between high- and low-performance tumbler pigeons after exercise, and to use metabolomics and metagenomics technique...
Fish gut microbiota is essential for maintaining host physiological health but is constantly threatened by environmental chemicals. Diphenyl phosphate (DPhP), a major degradation product of organophosphate flame retardants and an environmental pollut...
The oak lace bug, Corythucha arcuata (Say, 1832) (Hemiptera: Tingidae), has emerged as an ecologically disruptive invasive pest across Eurasian Quercus forests, severely impairing foliar photosynthetic capacity and overall woodland vitality. By syste...
Mitochondrial codon usage and selective pressures drive adaptive evolution and translation efficiency. This study provides insights into the evolutionary constraints shaping 13 core mitochondrial proteins in Corvides, based on 117 species, including...
The Mediterranean Sea represents a hotspot of non-indigenous fish species introductions. Here, we provide a comprehensive bibliographic synthesis on five Lessepsian fish invaders—Fistularia commersonii, Lagocephalus sceleratus, Pterois miles, S...
Adoxophyes orana is a major leafroller pest that damages fruit trees from Asia to Central Europe. The sex pheromone (SP) of A. orana comprises Z9-14:Ac, Z11-14:Ac, Z9-14:OH, Z11-14:OH, and E9-14: Ac. In this study, we characterized the ligand-binding...
The rhizosphere bacterial community is an important determinant of plant health and disease resistance. To investigate bacterial community characteristics associated with Fusarium wilt resistance, we used full-length 16S rRNA amplicon sequencing to c...
Sex- and gender-based immune differences have often been interpreted through a male–female biological binary, overlooking how endocrine signaling dynamically shapes immune function. Gender-affirming hormone therapy (GAHT) offers a unique physio...
Waterlogging-induced hypoxic stress severely impairs vegetative growth and crop yield of melon (Cucumis melo L.). The formation of adventitious roots represents a critical morphological adaptive strategy for melon seedlings to alleviate hypoxic damag...
No previous studies have characterized testicular polyamine metabolism across specific cell populations, including Sertoli cells, testicular peritubular cells, Leydig cells, germ cells, and testicular macrophages, during testicular maturation and agi...
Melanin is a natural biopolymer with broad biological activities, yet research on melanin from the medicinal fungus Ophiocordyceps sinensis remains insufficient. In this study, two melanin fractions, TZ-a and TZ-b, were isolated from its fermentation...
Iron overload is a recognized risk factor for female reproductive dysfunction, yet the underlying cellular and molecular mechanisms remain incompletely understood. In this study, the effects of iron overload on ovarian granulosa cells were investigat...
Soil microplastics undergo aging, but how aging modifies their effects on soil bacterial communities remains unclear. Here, we conducted a 180-day incubation experiment with no PVC (CK), pristine PVC microplastics (IP), and UV-aged PVC microplastics...
Neuropathic pain is a chronic condition resulting from injury or dysfunction of the nervous system, characterized by hyperalgesia, allodynia, and persistent alterations in sensory perception. Neuroligins, a family of postsynaptic adhesion proteins es...
Gliomas are the most common and aggressive primary brain tumours, with glioblastoma (GB) exhibiting a poor prognosis and limited therapeutic response. Dysregulation of intracellular ion homeostasis, particularly Ca2+ signalling, has emerged as a key...
The rapid growth of avian genomic resources has created a field rich in genomic data but still in need of integrative synthesis. Here, we review evidence linking four colour-producing systems—melanin, carotenoids, psittacofulvins and structural...
Berberine (BBR), a plant-derived isoquinoline alkaloid, exhibits broad-spectrum antibacterial activity, but its molecular mechanisms against Aeromonas hydrophila remain unclear. This study investigated the antibacterial action and underlying mechanis...
Brain plasticity is often described as the capacity of the nervous system to change in response to development, experience, injury, disease, or treatment. That definition is useful, but it can obscure two clinically important points: plasticity is bi...
Understanding vegetation phenology is critical for assessing the impacts of climate change, particularly in regions vulnerable to environmental fluctuations. This study investigates the temporal trends and spatial variability of the start of photosyn...
The pine sawyer beetle (Monochamus alternatus Hope, 1842) is a major vector of the pinewood nematode [Bursaphelenchus xylophilus (Steiner & Buhrer, 1934) Nickle, 1970]. A total of 119 cuticular protein (CP) genes were identified from the M. alter...
Isodon serra is a medicinal plant distributed in the Lingnan region of China. However, I. serra seeds are sensitive to heat, limiting germination in Lingnan’s climate. Seed priming technology provides an effective means to address this problem....
Deoxynivalenol (DON), a prevalent mycotoxin, induces intestinal and hepatic injury. Fructus mume extract (FME) possesses bioactive properties, yet its protective role against DON remains unclear. This study aimed to investigate the protective mechani...
Plant bioreactors offer low production costs, high biosafety, and facile scalability, making tomato an excellent platform for the expression of bioactive proteins. Lactoferrin (LF) possesses a wide range of biological activities; however, its product...
Phase transition or phase separation occurs in cells and tissues in many physiological events, such as protein granules (P granules) in early C. elegans development. Inappropriate phase transition is often associated with pathologic processes such as...
Palmitic acid (PA) can be used as a substitute for fish oil in aquaculture; however, excessive intake can easily cause lipotoxic liver damage in animals, and the progression of non-alcoholic fatty liver disease (NAFLD) is closely associated with it....
Precise site-specific ligand design remains a major challenge in structure-based drug discovery. Most existing approaches screen ligands against binding pockets identified from static protein structures obtained by X-ray crystallography, NMR spectros...
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