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30 January 2026

Electrochemical Sensors as a Tool for Taste Perception in Pharmaceutical Products: Advances and Perspectives

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Innovatech Laboratory, Aché Laboratórios Farmacêuticos, Rodovia Presidente Dutra—Porto da Igreja, Guarulhos 07034-904, SP, Brazil
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Author to whom correspondence should be addressed.
These authors contributed equally to this work.
This article belongs to the Special Issue Label-Free Electrochemical Biosensing

Abstract

Taste masking in pharmaceutical products is a complex and subjective process that requires reliable evaluation methods. This review focuses on the electronic tongue (e-tongue), an emerging sensor-based technology designed to mimic human taste perception without the need for human panels. E-tongue systems provide objective data to support the development of palatable formulations. In this review, we discuss the principles, types of e-tongue devices, data processing approaches, and their applications in pharmaceutical research. By comparing e-tongue performance with human taste assessment, we highlight its potential as a complementary tool to traditional in vitro assays, accelerating formulation development and improving patient adherence.

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