Journal of Functional Biomaterials, Volume 15, Issue 8
2024 August - 37 articles
Cover Story: This study introduces innovative core–shell bioresorbable scaffolds, in which a stiff 3D-printed poly(lactic acid) lattice core ensures mechanical support while a bioactive gelatin–chitosan hydrogel is nested throughout the core via grafting and crosslinking to support cell proliferation and differentiation. The scaffolds can be tailored for a specific application by designing the lattice geometry and the core–shell ratio, which both significantly affect its mechanical performance and bioresorption. The core–shell structural stability and mechanical properties are maintained during in vitro degradation experiments. Moreover, the scaffolds highly support hMSCs’ growth and osteogenic differentiation, promoting hydroxyapatite formation. View this paper - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
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