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Journal of Clinical Medicine, Volume 5, Issue 7

July 2016 - 6 articles

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Articles (6)

  • Review
  • Open Access
194 Citations
15,861 Views
14 Pages

EMT in Breast Carcinoma—A Review

  • Joema Felipe Lima,
  • Sharon Nofech-Mozes,
  • Jane Bayani and
  • John M. S. Bartlett

The epithelial to mesenchymal transition (EMT) is a cellular program that is involved in embryonic development; wound healing, but also in tumorigenesis. Breast carcinoma (BC) is the most common cancer in women worldwide, and the majority of deaths (...

  • Article
  • Open Access
3 Citations
5,190 Views
13 Pages

Increased vascular angiotensin-converting enzyme (ACE) activity and oxidative stress are present in young Syrian cardiomyopathic hamsters (SCH) before the clinical manifestation of heart failure (HF). The developmental time-course of these alteration...

  • Feature Paper
  • Review
  • Open Access
237 Citations
19,973 Views
34 Pages

Mechanisms of TGFβ-Induced Epithelial–Mesenchymal Transition

  • Aristidis Moustakas and
  • Carl-Henrik Heldin

Transitory phenotypic changes such as the epithelial–mesenchymal transition (EMT) help embryonic cells to generate migratory descendants that populate new sites and establish the distinct tissues in the developing embryo. The mesenchymal descendants...

  • Review
  • Open Access
294 Citations
59,526 Views
28 Pages

Heart Failure: Diagnosis, Management and Utilization

  • Arati A. Inamdar and
  • Ajinkya C. Inamdar

Despite the advancement in medicine, management of heart failure (HF), which usually presents as a disease syndrome, has been a challenge to healthcare providers. This is reflected by the relatively higher rate of readmissions along with increased mo...

  • Article
  • Open Access
26 Citations
6,039 Views
9 Pages

The Impact of Remote Ischemic Preconditioning on Arterial Stiffness and Heart Rate Variability in Patients with Angina Pectoris

  • Naufal Zagidullin,
  • Elena Scherbakova,
  • Yuliana Safina,
  • Rustem Zulkarneev and
  • Shamil Zagidullin

Remote ischemic preconditioning (RIPC) is the set of ischemia episodes that protects against subsequent periods of prolonged ischemia through the cascade of adaptive responses; however, the mechanisms of RIPC are not entirely clear. Here, we aimed to...

  • Article
  • Open Access
32 Citations
6,611 Views
10 Pages

An Evaluation of Acylated Ghrelin and Obestatin Levels in Childhood Obesity and Their Association with Insulin Resistance, Metabolic Syndrome, and Oxidative Stress

  • Maryam Razzaghy-Azar,
  • Mitra Nourbakhsh,
  • Abdolreza Pourmoteabed,
  • Mona Nourbakhsh,
  • Davod Ilbeigi and
  • Mohsen Khosravi

Background: Ghrelin is a 28-amino acid peptide with an orexigenic property, which is predominantly produced by the stomach. Acylated ghrelin is the active form of this hormone. Obestatin is a 23-amino acid peptide which is produced by post-translatio...

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J. Clin. Med. - ISSN 2077-0383