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Natural Compounds as Beneficial Antioxidant Agents in Neurodegenerative Disorders: A Focus on Alzheimer’s Disease

1
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, 90127 Palermo, Italy
2
Department of Neuroscience and Cell Biology, University of Palermo, 90127 Palermo, Italy
*
Author to whom correspondence should be addressed.
Antioxidants 2019, 8(12), 608; https://doi.org/10.3390/antiox8120608
Received: 24 October 2019 / Revised: 19 November 2019 / Accepted: 27 November 2019 / Published: 30 November 2019
The positive role of nutrition in chronic neurodegenerative diseases (NDs) suggests that dietary interventions represent helpful tools for preventing NDs. In particular, diets enriched with natural compounds have become an increasingly attractive, non-invasive, and inexpensive option to support a healthy brain and to potentially treat NDs. Bioactive compounds found in vegetables or microalgae possess special properties able to counteract oxidative stress, which is involved as a triggering factor in neurodegeneration. Here, we briefly review the relevant experimental data on curcuminoids, silymarin, chlorogenic acid, and compounds derived from the microalga Aphanizomenon flos aquae (AFA) which have been demonstrated to possess encouraging beneficial effects on neurodegeneration, in particular on Alzheimer’s disease models. View Full-Text
Keywords: neurodegenerative diseases; Alzheimer’s disease; curcuminoids; silymarin; chlorogenic acid; microalgae; Aphanizomenon flos aquae neurodegenerative diseases; Alzheimer’s disease; curcuminoids; silymarin; chlorogenic acid; microalgae; Aphanizomenon flos aquae
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Amato, A.; Terzo, S.; Mulè, F. Natural Compounds as Beneficial Antioxidant Agents in Neurodegenerative Disorders: A Focus on Alzheimer’s Disease. Antioxidants 2019, 8, 608.

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