Measurement of the Clinical Effects of a Marine Fish Extract on Periodontal Healing—A Preliminary Clinical Interventional Study

Pușcașu, Cristina Gabriela; Caraiane, Aureliana; Dumea, Elena; Șachir, Erdogan Elvis; Raftu, Gheorghe; Pușcașu, Radu Andrei; Bartok-Nicolae, Cristina; Cernei, Eduard Radu; Sachelarie, Liliana; Hurjui, Liliana Loredana

doi:10.3390/app12020677

Open AccessArticle

Measurement of the Clinical Effects of a Marine Fish Extract on Periodontal Healing—A Preliminary Clinical Interventional Study

by

Cristina Gabriela Pușcașu

^1,*,†

,

Aureliana Caraiane

^1,†,

Elena Dumea

^2,†

,

Erdogan Elvis Șachir

^1,†,

Gheorghe Raftu

^1,†,

Radu Andrei Pușcașu

^3,†,

Cristina Bartok-Nicolae

^1,*,†

,

Eduard Radu Cernei

^4,*,†,

Liliana Sachelarie

^5,*,†

and

Liliana Loredana Hurjui

^4,*,†

¹

Faculty of Dental Medicine, “Ovidius” University Constanta, 7 Ilarie Voronca Street, 900684 Constanța, Romania

²

Faculty of Medicine, “Ovidius” University Constanta, 1 Aleea Universității Corp B, 900470 Constanța, Romania

³

Faculty of Medicine, University of Medicine and Pharmacy Carol Davila, 8, Bvld. Eroii Sanitari, 050474 Bucharest, Romania

⁴

Faculty of Dental Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania

⁵

Faculty of Dental Medicine, Apollonia University, Păcurari 11, 700511 Iasi, Romania

^*

Authors to whom correspondence should be addressed.

^†

These authors contributed equally to this work.

Appl. Sci. 2022, 12(2), 677; https://doi.org/10.3390/app12020677

Submission received: 23 December 2021 / Revised: 7 January 2022 / Accepted: 9 January 2022 / Published: 11 January 2022

(This article belongs to the Special Issue Applied Interdisciplinarity Medical Areas in Maintaining Oral Health)

Download

Browse Figures

Review Reports Versions Notes

Abstract

The aim of the study was to assess the clinical effects of periodontal healing using a Romanian pharmaceutical compound of marine fish extract (Alflutop^®). Adults with periodontal disease were included in the study group. Gingival inflammation, the degree of tooth mobility, and probing depth (PD) were recorded for each patient before and after therapy. Patients were divided into two groups: group I—after scaling and root planing (SRP), patients followed therapy with marine fish extract, Alflutop^®, group II—SRP therapy alone. Statistically significant differences between groups in terms of gingival inflammation reduction (p = 0.045) were found. Tooth mobility reduction, as well as PD improvement, were also noticed after the therapy (p = 0.001), but no statistically significant differences among PD reduction rates were found (p = 0.356). Alflutop^® has proven a certain therapeutic efficiency in the treatment of periodontitis in terms of reduction in the clinical signs of inflammation and tooth mobility.

Keywords: periodontitis; periodontal healing; marine fish extract; Alflutop

Share and Cite

MDPI and ACS Style

Pușcașu, C.G.; Caraiane, A.; Dumea, E.; Șachir, E.E.; Raftu, G.; Pușcașu, R.A.; Bartok-Nicolae, C.; Cernei, E.R.; Sachelarie, L.; Hurjui, L.L. Measurement of the Clinical Effects of a Marine Fish Extract on Periodontal Healing—A Preliminary Clinical Interventional Study. Appl. Sci. 2022, 12, 677. https://doi.org/10.3390/app12020677

AMA Style

Pușcașu CG, Caraiane A, Dumea E, Șachir EE, Raftu G, Pușcașu RA, Bartok-Nicolae C, Cernei ER, Sachelarie L, Hurjui LL. Measurement of the Clinical Effects of a Marine Fish Extract on Periodontal Healing—A Preliminary Clinical Interventional Study. Applied Sciences. 2022; 12(2):677. https://doi.org/10.3390/app12020677

Chicago/Turabian Style

Pușcașu, Cristina Gabriela, Aureliana Caraiane, Elena Dumea, Erdogan Elvis Șachir, Gheorghe Raftu, Radu Andrei Pușcașu, Cristina Bartok-Nicolae, Eduard Radu Cernei, Liliana Sachelarie, and Liliana Loredana Hurjui. 2022. "Measurement of the Clinical Effects of a Marine Fish Extract on Periodontal Healing—A Preliminary Clinical Interventional Study" Applied Sciences 12, no. 2: 677. https://doi.org/10.3390/app12020677

APA Style

Pușcașu, C. G., Caraiane, A., Dumea, E., Șachir, E. E., Raftu, G., Pușcașu, R. A., Bartok-Nicolae, C., Cernei, E. R., Sachelarie, L., & Hurjui, L. L. (2022). Measurement of the Clinical Effects of a Marine Fish Extract on Periodontal Healing—A Preliminary Clinical Interventional Study. Applied Sciences, 12(2), 677. https://doi.org/10.3390/app12020677

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Menu

Measurement of the Clinical Effects of a Marine Fish Extract on Periodontal Healing—A Preliminary Clinical Interventional Study

Abstract

Share and Cite

Article Metrics

Article Access Statistics

Further Information

Guidelines

MDPI Initiatives

Follow MDPI