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Medical Sciences, Volume 7, Issue 1

2019 January - 12 articles

Cover Story: Traumatic Brain Injury (TBI) is defined by the Centers for Disease Control and Prevention (CDC) as a “bump, blow, or jolt to the head, or penetrating head injury, that results in disruption of the normal function of the brain”. According to the American College of Surgeons, for patients with suspected TBI, the primary goal of treatment is to prevent the secondary TBI. In this review, we discuss the neuroanatomy, type, and severity of TBI, and criteria for neuroimaging. It is widely accepted that for moderate or severe TBI, the most appropriate initial neuroimaging study is a non-contrast CT scan of the head. We also discuss advanced neuroimaging techniques including perfusion imaging and diffusion tensor imaging, as they may help in the future with the clinical care of TBI patients. View Paper here.
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Articles (12)

  • Review
  • Open Access
32 Citations
8,974 Views
14 Pages

21 January 2019

Traumatic brain injury (TBI) is a major healthcare problem and a major burden to society. The identification of a TBI can be challenging in the prehospital setting, particularly in elderly patients with unobserved falls. Errors in triage on scene can...

(This article belongs to the Special Issue Traumatic Brain Injury)
  • Article
  • Open Access
5 Citations
5,207 Views
11 Pages

Determining an Appropriate Time to Start Prophylactic Treatment with Intranasal Corticosteroids in Japanese Cedar Pollinosis

  • Takenori Haruna,
  • Shin Kariya,
  • Takaya Higaki,
  • Sei-ichiro Makihara and ,
  • Kengo Kanai,
  • Yasutoshi Komatsubara,
  • Aiko Oka,
  • Kazunori Nishizaki and
  • Mitsuhiro Okano
  • + 4 authors+ 0 author

15 January 2019

Prophylactic treatment with intranasal corticosteroids is effective for pollen-induced seasonal allergic rhinitis. However, the appropriate time to start this treatment remains unclear. We performed a double-blinded, randomized, placebo-controlled tr...

(This article belongs to the Special Issue Allergic Rhinitis: Epidemiology, Prevention and Management)
  • Article
  • Open Access
3 Citations
4,269 Views
11 Pages

14 January 2019

Doctors from the United Kingdom are increasingly involved in international medical volunteerism in low- and middle-income countries (LMICs). Although supported by government policy this practice lacks infrastructure and coordination. Volunteer activi...

(This article belongs to the Special Issue Recent Advances in Health Improvement Strategies)
  • Review
  • Open Access
21 Citations
12,404 Views
10 Pages

Management of Acute Respiratory Failure Due to Community-Acquired Pneumonia: A Systematic Review

  • Nicolò Maria Vanoni,
  • Manuela Carugati,
  • Noemi Borsa,
  • Giovanni Sotgiu and ,
  • Laura Saderi,
  • Andrea Gori,
  • Marco Mantero,
  • Stefano Aliberti and
  • Francesco Blasi
  • + 4 authors+ 0 author

14 January 2019

Community-acquired pneumonia (CAP) is a leading cause of mortality worldwide. CAP mortality is driven by the development of sepsis and acute respiratory failure (ARF). We performed a systematic review of the available English literature published in...

(This article belongs to the Section Pneumology and Respiratory Diseases)
  • Review
  • Open Access
3 Citations
4,025 Views
11 Pages

9 January 2019

The ongoing growth of the international occurrence of depression and its ability to co-occur with other serious medical disorders, such as heart disease, cancer, diabetes, and Parkinson’s disease, is a current public health problem. Inhibitor o...

  • Article
  • Open Access
9 Citations
11,717 Views
8 Pages

8 January 2019

The aim of this study was to evaluate the effectiveness of a two-step algorithm for the detection of Clostridium difficile infection. Setting and Design: A two-step testing algorithm was evaluated for testing stool samples from patients suspected of...

  • Review
  • Open Access
15 Citations
7,262 Views
23 Pages

Spotlight on the Transglutaminase 2-Heparan Sulfate Interaction

  • Giulia Furini and
  • Elisabetta A.M. Verderio

4 January 2019

Heparan sulfate proteoglycans (HSPGs), syndecan-4 (Sdc4) especially, have been suggested as potential partners of transglutaminase-2 (TG2) in kidney and cardiac fibrosis, metastatic cancer, neurodegeneration and coeliac disease. The proposed role for...

(This article belongs to the Special Issue Transglutaminases in Health and Disease)
  • Article
  • Open Access
1 Citations
3,953 Views
8 Pages

Analysis of Antioxidant Consumption, Body Mass Index and the Waist-Hip Ratio in Early Postmenopause

  • Carlos A. Jiménez-Zamarripa,
  • Liliana Anguiano-Robledo,
  • Patricia Loranca-Moreno,
  • M. Esther Ocharan-Hernández and
  • Claudia C. Calzada-Mendoza

3 January 2019

Oxidative stress is present in early postmenopause. Antioxidants, present in food, avoid or limit the damage caused by free radicals. The aim of this study was to analyze whether the consumption of vitamin A, vitamin C, and Selenium was adequate in p...

  • Article
  • Open Access
10 Citations
4,307 Views
10 Pages

Leptin Gene G2548A Polymorphism among Mongolians with Metabolic Syndrome

  • Batnaran Dagdan,
  • Ariunbold Chuluun-Erdene,
  • Orgil Sengeragchaa,
  • Munkhzol Malchinkhuu and
  • Munkhtsetseg Janlav

21 December 2018

Metabolic syndrome (MetS) corresponds with multiple risk factors. Many studies have indicated that MetS significantly increases the risk of cardiovascular diseases and type 2 diabetes (T2D). The prevalence of MetS was estimated to be one third of the...

(This article belongs to the Section Endocrinology and Metabolic Diseases)
  • Article
  • Open Access
5 Citations
4,443 Views
8 Pages

Correlation Between Soluble Endothelial Adhesion Molecules and Nitric Oxide Metabolites in Sickle Cell Disease

  • Charles Antwi-Boasiako,
  • John Ahenkorah,
  • Eric S. Donkor,
  • Bartholomew Dzudzor and ,
  • Gifty B. Dankwah,
  • Kate H. Otu,
  • Robert Aryee,
  • Charles Hayfron-Benjamin and
  • Andrew D. Campbell
  • + 4 authors+ 0 author

20 December 2018

Nitric Oxide (NO) and soluble adhesion molecules are promising biomarkers, which predict endothelial dysfunction in sickle cell disease (SCD). Several studies have investigated the relationship between NO (as well as its metabolites) and endothelial...

  • Feature Paper
  • Review
  • Open Access
45 Citations
26,305 Views
19 Pages

Neuroimaging of Traumatic Brain Injury

  • David B. Douglas,
  • Tae Ro,
  • Thomas Toffoli,
  • Bennet Krawchuk and ,
  • Jonathan Muldermans,
  • James Gullo,
  • Adam Dulberger,
  • Ariana E. Anderson,
  • Pamela K. Douglas and
  • Max Wintermark
  • + 5 authors+ 0 author

20 December 2018

The purpose of this article is to review conventional and advanced neuroimaging techniques performed in the setting of traumatic brain injury (TBI). The primary goal for the treatment of patients with suspected TBI is to prevent secondary injury. In...

(This article belongs to the Special Issue Traumatic Brain Injury)
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Med. Sci. - ISSN 2076-3271