Next Article in Journal
Plasma Membrane Potential of Candida albicans Measured by Di-4-ANEPPS Fluorescence Depends on Growth Phase and Regulatory Factors
Next Article in Special Issue
Short-Term Probiotic Administration Increases Fecal-Anti Candida Activity in Healthy Subjects
Previous Article in Journal
The Anti-Rotaviral Activity of Low Molecular Weight and Non-Proteinaceous Substance from Bifidobacterium longum BORI Cell Extract
Previous Article in Special Issue
The Foodborne Strain Lactobacillus fermentum MBC2 Triggers pept-1-Dependent Pro-Longevity Effects in Caenorhabditis elegans
Open AccessArticle

Inhibition of Nitric Oxide Production, Oxidative Stress Prevention, and Probiotic Activity of Lactic Acid Bacteria Isolated from the Human Vagina and Fermented Food

MEDIOGEN, Co., Ltd., Seoul 04146, Korea
*
Author to whom correspondence should be addressed.
Microorganisms 2019, 7(4), 109; https://doi.org/10.3390/microorganisms7040109
Received: 21 January 2019 / Revised: 16 April 2019 / Accepted: 17 April 2019 / Published: 23 April 2019
(This article belongs to the Special Issue Probiotics: From Quality Assessment to Microbial Ecology)
In this study, lactic acid bacteria (LAB) with antioxidative and probiotic activities were isolated from the vaginas of Korean women and from fermented food. Among 34 isolated LAB strains, four strains (MG4221, MG4231, MG4261, and MG4270) exhibited inhibitory activity against nitric oxide production. The MG4221 and MG4270 strains were identified as Lactobacillus plantarum, and MG4231 and MG4261 were identified as Lactobacillus fermentum. These strains were able to tolerate pepsin and pancreatin, which is required for probiotic potential. The antioxidant effects of culture filtrates obtained from selected strains included 2,2-diphenyl-1-picryl-hydrazyl (DPPH) radical scavenging capacity. Most of the culture filtrates had effective DPPH scavenging activity.In conclusion, the selected strains have significant activities and are potentially applicable to the development of functional foods. These strains might also contribute to the prevention and control of several diseases associated with oxidative stress, when used as functional probiotics. View Full-Text
Keywords: nitric oxide; lactic acid bacteria; DPPH; probiotics nitric oxide; lactic acid bacteria; DPPH; probiotics
Show Figures

Figure 1

MDPI and ACS Style

Kang, C.-H.; Han, S.H.; Kim, J.-S.; Kim, Y.; Jeong, Y.; Park, H.M.; Paek, N.-S. Inhibition of Nitric Oxide Production, Oxidative Stress Prevention, and Probiotic Activity of Lactic Acid Bacteria Isolated from the Human Vagina and Fermented Food. Microorganisms 2019, 7, 109.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop