Table of Contents
Lubricants, Volume 8, Issue 5 (May 2020) – 12 articles
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Cover Story (view full-size image) Total joint replacements undergo wear testing in mechanical simulators while submerged in [...] Read more. Total joint replacements undergo wear testing in mechanical simulators while submerged in proteinaceous solutions that mimic the environment of the body. However, lot variability of the natural lubricant ‘calf serum’ yields undesirable variance in testing outcomes. We found that bilirubin, a compound that gives calf serum the yellowish-orange color, increases wear of the joint, while fatty acids decrease wear. The increase in wear for bilirubin is caused by a conformational change of the protein ‘albumin’ in calf serum, which makes it more likely to form molecular bridges between joint counterfaces. The addition of fatty acids has the opposite effect. View this paper.