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Life, Volume 9, Issue 4

2019 December - 10 articles

Cover Story: To be accepted as "prebiotic", the process of making RNA must be simple. However, RNA seems intrinsically complicated, as are most proposals for its formation, involving multi-step sequences that need human intervention to manage self-reacting intermediates, orchestrate reagent addition, and schedule photon irradiation. However, some prebiotic chemistry is inevitable. Formaldehyde and trace glycolaldehyde almost certainly formed and reacted with volcanic SO2 to give semi-stable products. Rained into borate-containing aquifers, these products produced 5-carbon sugars like ribose. Mid-sized impacts intermittently created hazy atmospheres that delivered nucleobase precursors to those aquifers. With drying, mineral-organic interactions assemble phosphorylated nucleosides and oligomeric RNA from these. These chemistries suggest that RNA is an intrinsic outcome of simple chemistry on rocky planets. View this paper
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Articles (10)

  • Article
  • Open Access
14 Citations
6,400 Views
12 Pages

Survivability of Anhydrobiotic Cyanobacteria in Salty Ice: Implications for the Habitability of Icy Worlds

  • Barbara Cosciotti,
  • Amedeo Balbi,
  • Alessandra Ceccarelli,
  • Claudia Fagliarone,
  • Elisabetta Mattei,
  • Sebastian Emanuel Lauro,
  • Federico Di Paolo,
  • Elena Pettinelli and
  • Daniela Billi

22 November 2019

Two anhydrobiotic strains of the cyanobacterium Chroococcidiopsis, namely CCMEE 029 and CCMEE 171, isolated from the Negev Desert in Israel and from the Dry Valleys in Antarctica, were exposed to salty-ice simulations. The aim of the experiment was t...

(This article belongs to the Section Origins of Life)
  • Article
  • Open Access
53 Citations
10,105 Views
16 Pages

Prebiotic Chemistry that Could Not Not Have Happened

  • Steven A. Benner,
  • Hyo-Joong Kim and
  • Elisa Biondi

14 November 2019

We present a direct route by which RNA might have emerged in the Hadean from a fayalite–magnetite mantle, volcanic SO2 gas, and well-accepted processes that must have created substantial amounts of HCHO and catalytic amounts of glycolaldehyde i...

(This article belongs to the Special Issue Themed Issue Commemorating Prof. David Deamer's 80th Birthday)
  • Article
  • Open Access
18 Citations
6,365 Views
19 Pages

Membrane Lipid Composition and Amino Acid Excretion Patterns of Methanothermococcus okinawensis Grown in the Presence of Inhibitors Detected in the Enceladian Plume

  • Ruth-Sophie Taubner,
  • Lydia M. F. Baumann,
  • Thorsten Bauersachs,
  • Elisabeth L. Clifford,
  • Barbara Mähnert,
  • Barbara Reischl,
  • Richard Seifert,
  • Jörn Peckmann,
  • Simon K.-M. R. Rittmann and
  • Daniel Birgel

14 November 2019

Lipids and amino acids are regarded as important biomarkers for the search for extraterrestrial life in the Solar System. Such biomarkers may be used to trace methanogenic life on other planets or moons in the Solar System, such as Saturn’s icy...

(This article belongs to the Section Origins of Life)
  • Review
  • Open Access
11 Citations
8,416 Views
10 Pages

Lipid-Assisted Polymerization of Nucleotides

  • Felix Olasagasti and
  • Sudha Rajamani

5 November 2019

In addition to being one of the proponents of the “Lipid World hypothesis”, David Deamer, together with other colleagues, pioneered studies involving formation of RNA-like oligomers from their ‘non-activated’, prebiotically pl...

(This article belongs to the Special Issue Themed Issue Commemorating Prof. David Deamer's 80th Birthday)
  • Article
  • Open Access
5 Citations
5,091 Views
11 Pages

Detection of Biological Bricks in Space. The Case of Adenine in Silica Aerogel

  • Aline Percot,
  • Emilie-Laure Zins,
  • Amélie Al Araji,
  • Anh-Tu Ngo,
  • Jacques Vergne,
  • Makoto Tabata,
  • Akihiko Yamagishi and
  • Marie-Christine Maurel

26 October 2019

Space missions using probes to return dust samples are becoming more frequent. Dust collectors made of silica aerogel blocks are used to trap and bring back extraterrestrial particles for analysis. In this work, we show that it is possible to detect...

(This article belongs to the Special Issue Themed Issue Commemorating Prof. David Deamer's 80th Birthday)
  • Article
  • Open Access
18 Citations
6,488 Views
13 Pages

Wheat Space Odyssey: “From Seed to Seed”. Kernel Morphology

  • Ekaterina N. Baranova,
  • Margarita A. Levinskikh and
  • Alexander A. Gulevich

25 October 2019

The long-term autonomous existence of man in extraterrestrial conditions is associated with the need to cultivate plants—the only affordable and effective means for both providing oxygen and CO2 utilization, and providing one of the most habitu...

(This article belongs to the Section Origins of Life)
  • Article
  • Open Access
40 Citations
14,136 Views
17 Pages

Chemical Ecosystem Selection on Mineral Surfaces Reveals Long-Term Dynamics Consistent with the Spontaneous Emergence of Mutual Catalysis

  • Lena Vincent,
  • Michael Berg,
  • Mitchell Krismer,
  • Samuel T. Saghafi,
  • Jacob Cosby,
  • Talia Sankari,
  • Kalin Vetsigian,
  • H. James Cleaves and
  • David A. Baum

23 October 2019

How did chemicals first become organized into systems capable of self-propagation and adaptive evolution? One possibility is that the first evolvers were chemical ecosystems localized on mineral surfaces and composed of sets of molecular species that...

(This article belongs to the Special Issue Systems Protobiology: Origin of Life by Mutually Catalytic Networks)
  • Article
  • Open Access
23 Citations
6,761 Views
20 Pages

Nitrates as a Potential N Supply for Microbial Ecosystems in a Hyperarid Mars Analog System

  • Jianxun Shen,
  • Aubrey L. Zerkle,
  • Eva Stueeken and
  • Mark W. Claire

19 October 2019

Nitrate is common in Mars sediments owing to long-term atmospheric photolysis, oxidation, and potentially, impact shock heating. The Atacama Desert in Chile, which is the driest region on Earth and rich in nitrate deposits, is used as a Mars analog i...

(This article belongs to the Section Origins of Life)
  • Article
  • Open Access
11 Citations
5,819 Views
12 Pages

3 October 2019

The problem of the emergence and survival of self-replicating molecules in origin-of-life scenarios is plagued by the error catastrophe, which is usually escaped by considering effects of compartmentalization, as in the stochastic corrector model. By...

(This article belongs to the Section Origins of Life)
  • Review
  • Open Access
22 Citations
9,191 Views
12 Pages

20 September 2019

“The Lipid World” was published in 2001, stemming from a highly effective collaboration with David Deamer during a sabbatical year 20 years ago at the Weizmann Institute of Science in Israel. The present review paper highlights the benefi...

(This article belongs to the Special Issue Themed Issue Commemorating Prof. David Deamer's 80th Birthday)
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Life - ISSN 2075-1729